Ferrocenyl derivatives of the anthelmintic praziquantel: Design, synthesis, and biological evaluation

Journal of Medicinal Chemistry

Volumn 55, Issue 20, 2012, Pages 8790-8798

  Patra, Malay ^a   Ingram, Katrin ^b   Pierroz, Vanessa ^a   Ferrari, Stefano ^a   Spingler, Bernhard ^a   Keiser, Jennifer ^b   Gasser, Gilles ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY OF BASEL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISCHISTOSOMAL AGENT; CISPLATIN; FERROCENE DERIVATIVE; FERROCENYL PRAZIQUANTEL DERIVATIVE; PRAZIQUANTEL; UNCLASSIFIED DRUG;

ANTHELMINTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG ISOLATION; DRUG SCREENING; DRUG STABILITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; INCUBATION TEMPERATURE; INCUBATION TIME; MASS SPECTROMETRY; NONHUMAN; PLASMA; PROTON NUCLEAR MAGNETIC RESONANCE; RACEMIC MIXTURE; SCHISTOSOMA MANSONI; X RAY CRYSTALLOGRAPHY;

ANIMALS; CELL LINE, TUMOR; CRYSTALLOGRAPHY, X-RAY; FERROUS COMPOUNDS; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PRAZIQUANTEL; SCHISTOSOMA MANSONI; SCHISTOSOMICIDES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84867808752     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm301077m     Document Type: Article

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