메뉴 건너뛰기




Volumn 120, Issue 15, 2012, Pages 3118-3125

Mammalian target of rapamycin regulates neutrophil extracellular trap formation via induction of hypoxia-inducible factor 1 α

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LIPOPOLYSACCHARIDE; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA;

EID: 84867778778     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-01-405993     Document Type: Article
Times cited : (209)

References (46)
  • 1
    • 33344468233 scopus 로고    scopus 로고
    • Neutrophils and immunity: Challenges and opportunities
    • DOI 10.1038/nri1785
    • Nathan C. Neutrophils and immunity: challenges and opportunities. Nat Rev Immunol. 2006;6(3):173-182. (Pubitemid 43290987)
    • (2006) Nature Reviews Immunology , vol.6 , Issue.3 , pp. 173-182
    • Nathan, C.1
  • 3
    • 70349263992 scopus 로고    scopus 로고
    • Innate immunity turned inside-out: Antimicrobial defense by phagocyte extracellular traps
    • von Kockritz-Blickwede M, Nizet V. Innate immunity turned inside-out: antimicrobial defense by phagocyte extracellular traps. J Mol Med. 2009;87(8):775-783.
    • (2009) J Mol Med , vol.87 , Issue.8 , pp. 775-783
    • Von Kockritz-Blickwede, M.1    Nizet, V.2
  • 4
    • 67650638848 scopus 로고    scopus 로고
    • Impaired neutrophil extracellular trap (NET) formation: A novel innate immune deficiency of human neonates
    • Yost CC, Cody MJ, Harris ES, et al. Impaired neutrophil extracellular trap (NET) formation: a novel innate immune deficiency of human neonates. Blood. 2009;113(25):6419-6427.
    • (2009) Blood , vol.113 , Issue.25 , pp. 6419-6427
    • Yost, C.C.1    Cody, M.J.2    Harris, E.S.3
  • 5
    • 77956245423 scopus 로고    scopus 로고
    • PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps
    • Li P, Li M, Lindberg MR, Kennett MJ, Xiong N, Wang Y. PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps. J Exp Med. 2010;207(9):1853-1862.
    • (2010) J Exp Med , vol.207 , Issue.9 , pp. 1853-1862
    • Li, P.1    Li, M.2    Lindberg, M.R.3    Kennett, M.J.4    Xiong, N.5    Wang, Y.6
  • 7
    • 60849099332 scopus 로고    scopus 로고
    • Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation
    • Wang Y, Li M, Stadler S, et al. Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation. J Cell Biol. 2009;184(2):205-213.
    • (2009) J Cell Biol , vol.184 , Issue.2 , pp. 205-213
    • Wang, Y.1    Li, M.2    Stadler, S.3
  • 8
    • 78049496216 scopus 로고    scopus 로고
    • Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps
    • Papayannopoulos V, Metzler KD, Hakkim A, Zychlinsky A. Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps. J Cell Biol. 2010;191(3):677-691.
    • (2010) J Cell Biol , vol.191 , Issue.3 , pp. 677-691
    • Papayannopoulos, V.1    Metzler, K.D.2    Hakkim, A.3    Zychlinsky, A.4
  • 9
    • 78349277280 scopus 로고    scopus 로고
    • Statins enhance formation of phagocyte extracellular traps
    • Chow OA, von Kockritz-Blickwede M, Bright AT, et al. Statins enhance formation of phagocyte extracellular traps. Cell Host Microbe. 2010;8(5):445-454.
    • (2010) Cell Host Microbe , vol.8 , Issue.5 , pp. 445-454
    • Chow, O.A.1    Von Kockritz-Blickwede, M.2    Bright, A.T.3
  • 10
    • 77956426154 scopus 로고    scopus 로고
    • CXCR2 mediates NADPH oxidase-independent neutrophil extracellular trap formation in cystic fibrosis airway inflammation
    • Marcos V, Zhou Z, Yildirim AO, et al. CXCR2 mediates NADPH oxidase-independent neutrophil extracellular trap formation in cystic fibrosis airway inflammation. Nat Med. 2010;16(9):1018-1023.
    • (2010) Nat Med , vol.16 , Issue.9 , pp. 1018-1023
    • Marcos, V.1    Zhou, Z.2    Yildirim, A.O.3
  • 11
    • 77952007543 scopus 로고    scopus 로고
    • Mammalian target of rapamycin (mTOR): Conducting the cellular signaling symphony
    • Foster KG, Fingar DC. Mammalian target of rapamycin (mTOR): conducting the cellular signaling symphony. J Biol Chem. 2010;285(19):14071-14077.
    • (2010) J Biol Chem , vol.285 , Issue.19 , pp. 14071-14077
    • Foster, K.G.1    Fingar, D.C.2
  • 12
    • 78650510609 scopus 로고    scopus 로고
    • MTOR: From growth signal integration to cancer, diabetes and ageing
    • Zoncu R, Efeyan A, Sabatini DM. mTOR: from growth signal integration to cancer, diabetes and ageing. Nat Rev Mol Cell Biol. 2011;12(1):21-35.
    • (2011) Nat Rev Mol Cell Biol , vol.12 , Issue.1 , pp. 21-35
    • Zoncu, R.1    Efeyan, A.2    Sabatini, D.M.3
  • 14
  • 17
    • 54549089738 scopus 로고    scopus 로고
    • Hypoxia signalling through mTOR and the unfolded protein response in cancer
    • Wouters BG, Koritzinsky M. Hypoxia signalling through mTOR and the unfolded protein response in cancer. Nat Rev Cancer. 2008;8(11):851-864.
    • (2008) Nat Rev Cancer , vol.8 , Issue.11 , pp. 851-864
    • Wouters, B.G.1    Koritzinsky, M.2
  • 18
    • 22144493303 scopus 로고    scopus 로고
    • HIF-1alpha A master regulator of innate host defenses?
    • DOI 10.1172/JCI25740
    • Zarember KA, Malech HL. HIF-1alpha: a master regulator of innate host defenses? J Clin Invest. 2005;115(7):1702-1704. (Pubitemid 40979706)
    • (2005) Journal of Clinical Investigation , vol.115 , Issue.7 , pp. 1702-1704
    • Zarember, K.A.1    Malech, H.L.2
  • 20
    • 0043210428 scopus 로고    scopus 로고
    • Conditional suppression of cellular genes: Lentivirus vector-mediated drug-inducible RNA interference
    • DOI 10.1128/JVI.77.16.8957-8951.2003
    • Wiznerowicz M, Trono D. Conditional suppression of cellular genes: lentivirus vector-mediated drug-inducible RNA interference. J Virol. 2003;77(16):8957-8961. (Pubitemid 36936105)
    • (2003) Journal of Virology , vol.77 , Issue.16 , pp. 8957-8961
    • Wiznerowicz, M.1    Trono, D.2
  • 21
    • 79961071855 scopus 로고    scopus 로고
    • Genome wide RNA-seq analysis of human and mouse platelet transcriptomes
    • Rowley JW, Oler A, Tolley ND, et al. Genome wide RNA-seq analysis of human and mouse platelet transcriptomes. Blood. 2011.
    • (2011) Blood
    • Rowley, J.W.1    Oler, A.2    Tolley, N.D.3
  • 23
    • 32044465506 scopus 로고    scopus 로고
    • TOR signaling in growth and metabolism
    • DOI 10.1016/j.cell.2006.01.016, PII S0092867406001085
    • Wullschleger S, Loewith R, Hall MN. TOR signaling in growth and metabolism. Cell. 2006;124(3):471-484. (Pubitemid 43199434)
    • (2006) Cell , vol.124 , Issue.3 , pp. 471-484
    • Wullschleger, S.1    Loewith, R.2    Hall, M.N.3
  • 24
    • 33747819801 scopus 로고    scopus 로고
    • mTOR and cancer: Insights into a complex relationship
    • DOI 10.1038/nrc1974, PII NRC1974
    • Sabatini DM. mTOR and cancer: insights into a complex relationship. Nat Rev Cancer. 2006;6(9):729-734. (Pubitemid 44286004)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.9 , pp. 729-734
    • Sabatini, D.M.1
  • 25
    • 0030066934 scopus 로고    scopus 로고
    • Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation
    • Beretta L, Gingras AC, Svitkin YV, Hall MN, Sonenberg N. Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation. EMBO J. 1996;15(3):658-664. (Pubitemid 26044579)
    • (1996) EMBO Journal , vol.15 , Issue.3 , pp. 658-664
    • Beretta, L.1    Gingras, A.-C.2    Svitkin, Y.V.3    Hall, M.N.4    Sonenberg, N.5
  • 26
    • 15744400960 scopus 로고    scopus 로고
    • Signaling to translational control pathways: Diversity in gene regulation in inflammatory and vascular cells
    • DOI 10.1016/j.tcm.2004.10.004, PII S1050173804001756
    • Lindemann SW, Weyrich AS, Zimmerman GA. Signaling to translational control pathways: diversity in gene regulation in inflammatory and vascular cells. Trends Cardiovasc Med. 2005;15(1):9-17. (Pubitemid 40417540)
    • (2005) Trends in Cardiovascular Medicine , vol.15 , Issue.1 , pp. 9-17
    • Lindemann, S.W.1    Weyrich, A.S.2    Zimmerman, G.A.3
  • 27
    • 84856902335 scopus 로고    scopus 로고
    • Toll-like receptor 1/2 stimulation induces elevated interleukin-8 secretion in polymorphonuclear leukocytes isolated from preterm and term newborn infants
    • Thornton NL, Cody MJ, Yost CC. Toll-like receptor 1/2 stimulation induces elevated interleukin-8 secretion in polymorphonuclear leukocytes isolated from preterm and term newborn infants. Neonatology. 2011;101(2):140-146.
    • (2011) Neonatology , vol.101 , Issue.2 , pp. 140-146
    • Thornton, N.L.1    Cody, M.J.2    Yost, C.C.3
  • 28
    • 0035312747 scopus 로고    scopus 로고
    • Regulation of translation initiation by FRAP/mTOR
    • DOI 10.1101/gad.887201
    • Gingras AC, Raught B, Sonenberg N. Regulation of translation initiation by FRAP/mTOR. Genes Dev. 2001;15(7):807-826. (Pubitemid 32295062)
    • (2001) Genes and Development , vol.15 , Issue.7 , pp. 807-826
    • Gingras, A.-C.1    Raught, B.2    Sonenberg, N.3
  • 29
    • 0035012605 scopus 로고    scopus 로고
    • HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: Novel mechanism for HIF-1-mediated vascular endothelial growth factor expression
    • DOI 10.1128/MCB.21.12.3995-4004.2001
    • Laughner E, Taghavi P, Chiles K, Mahon PC, Semenza GL. HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression. Mol Cell Biol. 2001;21(12):3995-4004. (Pubitemid 32476461)
    • (2001) Molecular and Cellular Biology , vol.21 , Issue.12 , pp. 3995-4004
    • Laughner, E.1    Taghavi, P.2    Chiles, K.3    Mahon, P.C.4    Semenza, G.L.5
  • 31
    • 48849106973 scopus 로고    scopus 로고
    • ETosis: A novel cell death pathway
    • Wartha F, Henriques-Normark B. ETosis: a novel cell death pathway. Sci Signal. 2008;1(21):pe25.
    • (2008) Sci Signal , vol.1 , Issue.21
    • Wartha, F.1    Henriques-Normark, B.2
  • 33
    • 0142102521 scopus 로고    scopus 로고
    • Rapamycin inhibits GM-CSF-induced neutrophil migration
    • DOI 10.1016/S0014-5793(03)00828-7
    • Gomez-Cambronero J. Rapamycin inhibits GM-CSF-induced neutrophil migration. FEBS Lett. 2003;550(1-3):94-100. (Pubitemid 37281364)
    • (2003) FEBS Letters , vol.550 , Issue.1-3 , pp. 94-100
    • Gomez-Cambronero, J.1
  • 34
    • 80051941218 scopus 로고    scopus 로고
    • Innate immune collectin surfactant protein D simultaneously binds both neutrophil extracellular traps and carbohydrate ligands and promotes bacterial trapping
    • Douda DN, Jackson R, Grasemann H, Palaniyar N. Innate immune collectin surfactant protein D simultaneously binds both neutrophil extracellular traps and carbohydrate ligands and promotes bacterial trapping. J Immunol. 2011;187(4):1856-1865.
    • (2011) J Immunol , vol.187 , Issue.4 , pp. 1856-1865
    • Douda, D.N.1    Jackson, R.2    Grasemann, H.3    Palaniyar, N.4
  • 35
    • 70350004580 scopus 로고    scopus 로고
    • Restoration of NET formation by gene therapy in CGD controls aspergillosis
    • Bianchi M, Hakkim A, Brinkmann V, et al. Restoration of NET formation by gene therapy in CGD controls aspergillosis. Blood. 2009;114(13):2619-2622.
    • (2009) Blood , vol.114 , Issue.13 , pp. 2619-2622
    • Bianchi, M.1    Hakkim, A.2    Brinkmann, V.3
  • 36
    • 67349279881 scopus 로고    scopus 로고
    • Netting neutrophils in autoimmune small-vessel vasculitis
    • Kessenbrock K, Krumbholz M, Schonermarck U, et al. Netting neutrophils in autoimmune small-vessel vasculitis. Nat Med. 2009;15(6):623-625.
    • (2009) Nat Med , vol.15 , Issue.6 , pp. 623-625
    • Kessenbrock, K.1    Krumbholz, M.2    Schonermarck, U.3
  • 37
    • 70449107044 scopus 로고    scopus 로고
    • Extracellular histones are major mediators of death in sepsis
    • Xu J, Zhang X, Pelayo R, et al. Extracellular histones are major mediators of death in sepsis. Nat Med. 2009;15(11):1318-1321.
    • (2009) Nat Med , vol.15 , Issue.11 , pp. 1318-1321
    • Xu, J.1    Zhang, X.2    Pelayo, R.3
  • 38
    • 79960392810 scopus 로고    scopus 로고
    • Netting neutrophils induce endothelial damage, infiltrate tissues, and expose immunostimulatory molecules in systemic lupus erythematosus
    • Villanueva E, Yalavarthi S, Berthier CC, et al. Netting neutrophils induce endothelial damage, infiltrate tissues, and expose immunostimulatory molecules in systemic lupus erythematosus. J Immunol. 2011;187(1):538-552.
    • (2011) J Immunol , vol.187 , Issue.1 , pp. 538-552
    • Villanueva, E.1    Yalavarthi, S.2    Berthier, C.C.3
  • 39
    • 79952476762 scopus 로고    scopus 로고
    • Netting neutrophils are major inducers of type I IFN production in pediatric systemic lupus erythematosus
    • Garcia-Romo GS, Caielli S, Vega B, et al. Netting neutrophils are major inducers of type I IFN production in pediatric systemic lupus erythematosus. Sci Transl Med. 2011;3(73):73ra20.
    • (2011) Sci Transl Med , vol.3 , Issue.73
    • Garcia-Romo, G.S.1    Caielli, S.2    Vega, B.3
  • 40
    • 0036789574 scopus 로고    scopus 로고
    • Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin
    • Hudson CC, Liu M, Chiang GG, et al. Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin. Mol Cell Biol. 2002;22(20):7004-7014.
    • (2002) Mol Cell Biol , vol.22 , Issue.20 , pp. 7004-7014
    • Hudson, C.C.1    Liu, M.2    Chiang, G.G.3
  • 43
    • 34547134517 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1alpha is regulated by the mammalian target of rapamycin (mTOR) via an mTOR signaling motif
    • DOI 10.1074/jbc.M611782200
    • Land SC, Tee AR. Hypoxia-inducible factor 1alpha is regulated by the mammalian target of rapamycin (mTOR) via an mTOR signaling motif. J Biol Chem. 2007;282(28):20534-20543. (Pubitemid 47100043)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.28 , pp. 20534-20543
    • Land, S.C.1    Tee, A.R.2
  • 44
    • 39149133983 scopus 로고    scopus 로고
    • Pharmacologic augmentation of hypoxia-inducible factor-1alpha with mimosine boosts the bactericidal capacity of phagocytes
    • DOI 10.1086/524843
    • Zinkernagel AS, Peyssonnaux C, Johnson RS, Nizet V. Pharmacologic augmentation of hypoxia-inducible factor-1alpha with mimosine boosts the bactericidal capacity of phagocytes. J Infect Dis. 2008;197(2):214-217. (Pubitemid 351263439)
    • (2008) Journal of Infectious Diseases , vol.197 , Issue.2 , pp. 214-217
    • Zinkernagel, A.S.1    Peyssonnaux, C.2    Johnson, R.S.3    Nizet, V.4
  • 46
    • 49649107272 scopus 로고    scopus 로고
    • HIF and reactive oxygen species regulate oxidative phosphorylation in cancer
    • Hervouet E, Cizkova A, Demont J, et al. HIF and reactive oxygen species regulate oxidative phosphorylation in cancer. Carcinogenesis. 2008;29(8):1528-1537.
    • (2008) Carcinogenesis , vol.29 , Issue.8 , pp. 1528-1537
    • Hervouet, E.1    Cizkova, A.2    Demont, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.