Identification of antischistosomal leads by evaluating bridged 1,2,4,5-tetraoxanes, alphaperoxides, and tricyclic monoperoxides

Journal of Medicinal Chemistry

Volumn 55, Issue 20, 2012, Pages 8700-8711

  Ingram, Katrin ^a,b   Yaremenko, Ivan A ^c   Krylov, Igor B ^c   Hofer, Lorenz ^a,b   Terentev, Alexander O ^c   Keiser, Jennifer ^a,b  

^a SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

^b UNIVERSITY OF BASEL   (Switzerland)

^c N D ZELINSKY INSTITUTE OF ORGANIC CHEMISTRY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

1,2,4,5 TETRAOXANE DERIVATIVE; ADAMANTANE DERIVATIVE; ALKYL GROUP; ALPHAPEROXIDE DERIVATIVE; ANTISCHISTOSOMAL AGENT; ARTESUNATE; BRIDGED COMPOUND; HEME; HEMIN; PEROXIDE; PHENYL GROUP; PRAZIQUANTEL; TETRAOXANE DERIVATIVE; TRICYCLIC MONOPEROXIDE DERIVATIVE; UNCLASSIFIED DRUG;

ADOLESCENT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; DISEASE MODEL; DRUG IDENTIFICATION; DRUG SENSITIVITY; FEMALE; HELMINTHIASIS; IC 50; JUVENILE; MOUSE; NONHUMAN; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS MANSONI; SCHISTOSOMULUM; WORM;

ANIMALS; BICYCLO COMPOUNDS, HETEROCYCLIC; CHRONIC DISEASE; FEMALE; HEME; HEMIN; HETEROCYCLIC COMPOUNDS, 3-RING; HIGH-THROUGHPUT SCREENING ASSAYS; MICE; PEROXIDES; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS MANSONI; SCHISTOSOMICIDES; STRUCTURE-ACTIVITY RELATIONSHIP; TETRAOXANES;

EID: 84867769075     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm3009184     Document Type: Article

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