Calpain-1 knockout reveals broad effects on erythrocyte deformability and physiology

Biochemical Journal

Volumn 448, Issue 1, 2012, Pages 141-152

  Wieschhaus, Adam ^a,b,c   Khan, Anwar ^c   Zaidi, Asma ^d   Rogalin, Henry ^a   Hanada, Toshihiko ^a   Liu, Fei ^e   De Franceschi, Lucia ^f   Brugnara, Carlo ^g   Rivera, Alicia ^g   Chishti, Athar H ^a,b  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TUFTS UNIVERSITY   (United States)

^c UNIVERSITY OF ILLINOIS   (United States)

^d KANSAS CITY UNIVERSITY OF MEDICINE AND BIOSCIENCES   (United States)

^e HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^f UNIVERSITY OF VERONA   (Italy)

^g BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

Calcium pump; Calpain 1; Deformability; Erythrocyte; K+ Cl co transporter (KCC1); Spectrin

Indexed keywords

ADDUCIN; ADENOSINE TRIPHOSPHATASE (CALCIUM); ANKYRIN; CALMODULIN; CALPAIN 1; COTRANSPORTER; ERYTHROCYTE BAND 4.9 PROTEIN; SPECTRIN;

ANIMAL EXPERIMENT; ARTICLE; ATOMIC FORCE MICROSCOPY; CELL SURVIVAL; CONTROLLED STUDY; ECHINOCYTE; ERYTHROCYTE; ERYTHROCYTE DEFORMABILITY; ERYTHROCYTE FRAGILITY; GENE DELETION; GENOTYPE; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

ANIMALS; BLOOD PROTEINS; BUCLADESINE; CALCIMYCIN; CALCIUM SIGNALING; CALPAIN; CYTOSKELETON; ERYTHROCYTE AGING; ERYTHROCYTE DEFORMABILITY; ERYTHROCYTES; INTERMEDIATE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; MICROSCOPY, ATOMIC FORCE; OSMOTIC FRAGILITY; PLASMA MEMBRANE CALCIUM-TRANSPORTING ATPASES; SPHEROCYTES;

EID: 84867767486     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20121008     Document Type: Article

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