Combined deletion of mouse dematin-headpiece and β-adducin exerts a novel effect on the spectrin-actin junctions leading to erythrocyte fragility and hemolytic anemia

Journal of Biological Chemistry

Volumn 282, Issue 6, 2007, Pages 4124-4135

  Chen, Huiqing ^a   Khan, Anwar A ^a   Liu, Fei ^b   Gilligan, Diana M ^c   Peters, Luanne L ^d   Messick, Joanne ^e   Haschek Hock, Wanda M ^e   Li, Xuerong ^a   Ostafin, Agnes E ^b   Chishti, Athar H ^a,f  

^a UNIVERSITY OF ILLINOIS   (United States)

^b UNIVERSITY OF NOTRE DAME   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d JACKSON LABORATORY   (United States)

^e UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^f UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEMATIN-MEMBRANE; ERYTHROCYTE FRAGILITY; HEMOLYSIS; MUTANT MEMBRANE; SPECTRIN-ACTIN JUNCTIONS;

ATOMIC FORCE MICROSCOPY; BINDING ENERGY; BIOLOGICAL MEMBRANES; IONIC STRENGTH; MOLECULAR BIOLOGY; OSMOSIS;

PROTEINS;

ACTIN; ACTIN BINDING PROTEIN; BETA ADDUCIN; ERYTHROCYTE BAND 4.9 PROTEIN; HEMOGLOBIN; MEMBRANE PROTEIN; SPECTRIN; UNCLASSIFIED DRUG; ADDUCIN; CALMODULIN BINDING PROTEIN; EPB4.9 PROTEIN, MOUSE; PHOSPHOPROTEIN; PLASMA PROTEIN;

ANIMAL CELL; ARTICLE; ATOMIC FORCE MICROSCOPY; BLOOD ANALYSIS; CELL JUNCTION; CELL MEMBRANE; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOSKELETON; DISEASE SEVERITY; ERYTHROCYTE; ERYTHROCYTE FRAGILITY; ERYTHROID CELL; GENE DELETION; HEMATOCRIT; HEMOGLOBIN DETERMINATION; HEMOLYTIC ANEMIA; IN VIVO STUDY; IONIC STRENGTH; LIFESPAN; MEMBRANE BINDING; MEMBRANE VESICLE; MOLECULAR INTERACTION; MOUSE; NONHUMAN; OSMOTIC FRAGILITY; PARAMETER; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN PURIFICATION; PROTEIN STABILITY; RETICULOCYTE; STATISTICAL SIGNIFICANCE; UPREGULATION; ANIMAL; BLOOD; COMPARATIVE STUDY; DISEASE MODEL; ERYTHROCYTE MEMBRANE; GENETICS; HUMAN; METABOLISM; MOUSE MUTANT; PATHOLOGY; PHYSIOLOGY; ULTRASTRUCTURE;

MUS;

ACTINS; ANEMIA, HEMOLYTIC; ANIMALS; BLOOD PROTEINS; CALMODULIN-BINDING PROTEINS; DISEASE MODELS, ANIMAL; ERYTHROCYTE MEMBRANE; GENE DELETION; HUMANS; MICE; MICE, KNOCKOUT; MICROSCOPY, ATOMIC FORCE; OSMOTIC FRAGILITY; PHOSPHOPROTEINS; SPECTRIN;

EID: 33947495172     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M610231200     Document Type: Article

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