Protein kinase PKR amplification of interferon β induction occurs through initiation factor eIF-2α-mediated translational control

Journal of Biological Chemistry

Volumn 287, Issue 43, 2012, Pages 36384-36392

  McAllister, Christopher S ^a,b   Taghavi, Nora ^a   Samuel, Charles E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONTROL RESPONSE; CYCLOHEXIMIDES; CYTOSOLIC; GENE INDUCTION; INHIBITION MECHANISMS; INITIATION FACTORS; MAXIMAL INDUCTION; MEASLES VIRUS; PROTEIN KINASE; PROTEIN LEVEL; PROTEIN SYNTHESIS; RNA SENSOR; SIGNAL TRANSDUCTION PATHWAYS; VIRUS-INFECTED CELLS;

ANTIBIOTICS; ENZYMES; GENE EXPRESSION; GLYCOPROTEINS; PHOSPHORYLATION; RNA; SIGNAL TRANSDUCTION; VIRUSES;

PROTEINS;

BETA INTERFERON; CYCLOHEXIMIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN KINASE R; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ELF 2ALPHA; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; GENE AMPLIFICATION; GENE EXPRESSION; GENE INDUCTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PLASMID; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; EIF-2 KINASE; EUKARYOTIC INITIATION FACTOR-2; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; HELA CELLS; HUMANS; I-KAPPA B PROTEINS; INTERFERON-BETA; MEASLES VIRUS; NF-KAPPA B; PEPTIDE CHAIN INITIATION, TRANSLATIONAL; PHOSPHORYLATION; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 84867763154     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.390039     Document Type: Article

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