메뉴 건너뛰기




Volumn 13, Issue 10, 2012, Pages 12939-12951

Erythropoietin modulates autophagy signaling in the developing rat brain in an in vivo model of Oxygen-Toxicity

Author keywords

Autophagy; Developing brain; Erythropoietin; Hyperoxia; Oxidative stress

Indexed keywords

AUTOPHAGY PROTEIN 5; AUTOPHAGY RELATED GENE 12 PROTEIN; AUTOPHAGY RELATED GENE 3 PROTEIN; BECLIN 1; CELL PROTEIN; LIGHT CHAIN 3A II; LIGHT CHAIN 3B II; MICROTUBULE ASSOCIATED PROTEIN 1; RECOMBINANT ERYTHROPOIETIN; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; ATG3 PROTEIN, RAT; ATG5 PROTEIN, RAT; BECN1 PROTEIN, RAT; ERYTHROPOIETIN; LC3 PROTEIN, RAT; MICROTUBULE ASSOCIATED PROTEIN; PEPTIDE SYNTHASE; PROTEIN; RECOMBINANT PROTEIN;

EID: 84867763153     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms131012939     Document Type: Article
Times cited : (39)

References (52)
  • 1
    • 84857275218 scopus 로고    scopus 로고
    • Oxidative stress and autophagy: Mediators of synapse growth?
    • West, R.J.; Sweeney, S.T. Oxidative stress and autophagy: Mediators of synapse growth? Autophagy 2012, 8, 284-285.
    • (2012) Autophagy , vol.8 , pp. 284-285
    • West, R.J.1    Sweeney, S.T.2
  • 2
    • 62949091373 scopus 로고    scopus 로고
    • Autophagy: A lysosomal degradation pathway with a central role in health and disease
    • Eskelinen, E.L.; Saftig, P. Autophagy: A lysosomal degradation pathway with a central role in health and disease. Biochim. Biophys. Acta 2009, 1793, 664-673.
    • (2009) Biochim. Biophys. Acta , vol.1793 , pp. 664-673
    • Eskelinen, E.L.1    Saftig, P.2
  • 3
    • 72549095406 scopus 로고    scopus 로고
    • Regulation mechanisms and signaling pathways of autophagy
    • He, C.; Klionsky, D.J. Regulation mechanisms and signaling pathways of autophagy. Annu. Rev. Genet. 2009, 43, 67-93.
    • (2009) Annu. Rev. Genet , vol.43 , pp. 67-93
    • He, C.1    Klionsky, D.J.2
  • 4
    • 39849109338 scopus 로고    scopus 로고
    • Autophagy fights disease through cellular self-digestion
    • Mizushima, N.; Levine, B.; Cuervo, A.M.; Klionsky, D.J. Autophagy fights disease through cellular self-digestion. Nature 2008, 451, 1069-1075.
    • (2008) Nature , vol.451 , pp. 1069-1075
    • Mizushima, N.1    Levine, B.2    Cuervo, A.M.3    Klionsky, D.J.4
  • 5
    • 79251577061 scopus 로고    scopus 로고
    • The regulation of autophagy-Unanswered questions
    • Chen, Y.; Klionsky, D.J. The regulation of autophagy-Unanswered questions. J. Cell Sci. 2011, 124, 161-170.
    • (2011) J. Cell Sci , vol.124 , pp. 161-170
    • Chen, Y.1    Klionsky, D.J.2
  • 6
    • 84555195856 scopus 로고    scopus 로고
    • Autophagy, mitochondria and oxidative stress: Cross-talk and redox signalling
    • Lee, J.; Giordano, S.; Zhang, J. Autophagy, mitochondria and oxidative stress: Cross-talk and redox signalling. Biochem. J. 2012, 441, 523-540.
    • (2012) Biochem. J , vol.441 , pp. 523-540
    • Lee, J.1    Giordano, S.2    Zhang, J.3
  • 7
    • 84859135431 scopus 로고    scopus 로고
    • Autophagy-regulating small molecules and their therapeutic applications
    • Baek, K.H.; Park, J.; Shin, I. Autophagy-regulating small molecules and their therapeutic applications. Chem. Soc. Rev. 2012, 41, 3245-3263.
    • (2012) Chem. Soc. Rev , vol.41 , pp. 3245-3263
    • Baek, K.H.1    Park, J.2    Shin, I.3
  • 8
    • 34249037565 scopus 로고    scopus 로고
    • Crystal structure of the Bcl-XL-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein
    • Oberstein, A.; Jeffrey, P.D.; Shi, Y. Crystal structure of the Bcl-XL-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein. J. Biol. Chem. 2007, 282, 13123-13132.
    • (2007) J. Biol. Chem , vol.282 , pp. 13123-13132
    • Oberstein, A.1    Jeffrey, P.D.2    Shi, Y.3
  • 9
    • 79952628267 scopus 로고    scopus 로고
    • The Beclin 1 network regulates autophagy and apoptosis
    • Kang, R.; Zeh, H.J.; Lotze, M.T.; Tang, D. The Beclin 1 network regulates autophagy and apoptosis. Cell Death Differ. 2011, 18, 571-580.
    • (2011) Cell Death Differ , vol.18 , pp. 571-580
    • Kang, R.1    Zeh, H.J.2    Lotze, M.T.3    Tang, D.4
  • 10
    • 65249180744 scopus 로고    scopus 로고
    • The expression of beclin 1 is associated with favorable prognosis in stage IIIB colon cancers
    • Li, B.X.; Li, C.Y.; Peng, R.Q.; Wu, X.J.; Wang, H.Y.; Wan, D.S.; Zhu, X.F.; Zhang, X.S. The expression of beclin 1 is associated with favorable prognosis in stage IIIB colon cancers. Autophagy 2009, 5, 303-306.
    • (2009) Autophagy , vol.5 , pp. 303-306
    • Li, B.X.1    Li, C.Y.2    Peng, R.Q.3    Wu, X.J.4    Wang, H.Y.5    Wan, D.S.6    Zhu, X.F.7    Zhang, X.S.8
  • 11
    • 77951237303 scopus 로고    scopus 로고
    • The Beclin 1 interactome
    • He, C.; Levine, B. The Beclin 1 interactome. Curr. Opin. Cell Biol. 2010, 22, 140-149.
    • (2010) Curr. Opin. Cell Biol , vol.22 , pp. 140-149
    • He, C.1    Levine, B.2
  • 12
    • 77955884684 scopus 로고    scopus 로고
    • Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins
    • Itakura, E.; Mizushima, N. Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins. Autophagy 2010, 6, 764-776.
    • (2010) Autophagy , vol.6 , pp. 764-776
    • Itakura, E.1    Mizushima, N.2
  • 15
    • 36849089101 scopus 로고    scopus 로고
    • Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice
    • Komatsu, M.; Waguri, S.; Koike, M.; Sou, Y.S.; Ueno, T.; Hara, T.; Mizushima, N.; Iwata, J.; Ezaki, J.; Murata, S.; et al. Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice. Cell 2007, 131, 1149-1163.
    • (2007) Cell , vol.131 , pp. 1149-1163
    • Komatsu, M.1    Waguri, S.2    Koike, M.3    Sou, Y.S.4    Ueno, T.5    Hara, T.6    Mizushima, N.7    Iwata, J.8    Ezaki, J.9    Murata, S.10
  • 16
    • 51049118332 scopus 로고    scopus 로고
    • The Atg8 and Atg12 ubiquitin-like conjugation systems in macroautophagy. 'Protein modifications: Beyond the usual suspects' review series
    • Geng, J.; Klionsky, D.J. The Atg8 and Atg12 ubiquitin-like conjugation systems in macroautophagy. 'Protein modifications: Beyond the usual suspects' review series. EMBO Rep. 2008, 9, 859-864.
    • (2008) EMBO Rep , vol.9 , pp. 859-864
    • Geng, J.1    Klionsky, D.J.2
  • 19
    • 60749108379 scopus 로고    scopus 로고
    • Regulation of autophagy by reactive oxygen species (ROS): Implications for cancer progression and treatment
    • Azad, M.B.; Chen, Y.; Gibson, S.B. Regulation of autophagy by reactive oxygen species (ROS): Implications for cancer progression and treatment. Antioxid. Redox Signal. 2009, 11, 777-790.
    • (2009) Antioxid. Redox Signal , vol.11 , pp. 777-790
    • Azad, M.B.1    Chen, Y.2    Gibson, S.B.3
  • 20
    • 34247186472 scopus 로고    scopus 로고
    • Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4
    • Scherz-Shouval, R.; Shvets, E.; Fass, E.; Shorer, H.; Gil, L.; Elazar, Z. Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4. EMBO J. 2007, 26, 1749-1760.
    • (2007) EMBO J , vol.26 , pp. 1749-1760
    • Scherz-Shouval, R.1    Shvets, E.2    Fass, E.3    Shorer, H.4    Gil, L.5    Elazar, Z.6
  • 23
    • 84863210676 scopus 로고    scopus 로고
    • Stimulation of autophagy reduces neurodegeneration in a mouse model of human tauopathy
    • Schaeffer, V.; Lavenir, I.; Ozcelik, S.; Tolnay, M.; Winkler, D.T.; Goedert, M. Stimulation of autophagy reduces neurodegeneration in a mouse model of human tauopathy. Brain 2012, 135, 2169-2177.
    • (2012) Brain , vol.135 , pp. 2169-2177
    • Schaeffer, V.1    Lavenir, I.2    Ozcelik, S.3    Tolnay, M.4    Winkler, D.T.5    Goedert, M.6
  • 24
    • 0025283961 scopus 로고
    • Developmental cell death: Morphological diversity and multiple mechanisms
    • Clarke, P.G. Developmental cell death: Morphological diversity and multiple mechanisms. Anat. Embryol. (Berl.) 1990, 181, 195-213.
    • (1990) Anat. Embryol. (Berl.) , vol.181 , pp. 195-213
    • Clarke, P.G.1
  • 26
    • 50249189191 scopus 로고    scopus 로고
    • Neuronal injury in rat model of permanent focal cerebral ischemia is associated with activation of autophagic and lysosomal pathways
    • Wen, Y.D.; Sheng, R.; Zhang, L.S.; Han, R.; Zhang, X.; Zhang, X.D.; Han, F.; Fukunaga, K.; Qin, Z.H. Neuronal injury in rat model of permanent focal cerebral ischemia is associated with activation of autophagic and lysosomal pathways. Autophagy 2008, 4, 762-769.
    • (2008) Autophagy , vol.4 , pp. 762-769
    • Wen, Y.D.1    Sheng, R.2    Zhang, L.S.3    Han, R.4    Zhang, X.5    Zhang, X.D.6    Han, F.7    Fukunaga, K.8    Qin, Z.H.9
  • 28
    • 34548188741 scopus 로고    scopus 로고
    • Self-eating and self-killing: Crosstalk between autophagy and apoptosis
    • Maiuri, M.C.; Zalckvar, E.; Kimchi, A.; Kroemer, G. Self-eating and self-killing: Crosstalk between autophagy and apoptosis. Nat. Rev. Mol. Cell Biol. 2007, 8, 741-752.
    • (2007) Nat. Rev. Mol. Cell Biol , vol.8 , pp. 741-752
    • Maiuri, M.C.1    Zalckvar, E.2    Kimchi, A.3    Kroemer, G.4
  • 34
    • 79958746580 scopus 로고    scopus 로고
    • Neuroprotective potential of erythropoietin and its derivative carbamylated erythropoietin in periventricular leukomalacia
    • Liu, W.; Shen, Y.; Plane, J.M.; Pleasure, D.E.; Deng, W. Neuroprotective potential of erythropoietin and its derivative carbamylated erythropoietin in periventricular leukomalacia. Exp. Neurol. 2011, 230, 227-239.
    • (2011) Exp. Neurol , vol.230 , pp. 227-239
    • Liu, W.1    Shen, Y.2    Plane, J.M.3    Pleasure, D.E.4    Deng, W.5
  • 36
    • 80053313829 scopus 로고    scopus 로고
    • The potential role of JAK2/STAT3 pathway on the anti-apoptotic effect of recombinant human erythropoietin (rhEPO) after experimental traumatic brain injury of rats
    • Zhao, J.; Li, G.; Zhang, Y.; Su, X.; Hang, C. The potential role of JAK2/STAT3 pathway on the anti-apoptotic effect of recombinant human erythropoietin (rhEPO) after experimental traumatic brain injury of rats. Cytokine 2011, 56, 343-350.
    • (2011) Cytokine , vol.56 , pp. 343-350
    • Zhao, J.1    Li, G.2    Zhang, Y.3    Su, X.4    Hang, C.5
  • 39
    • 84866274756 scopus 로고    scopus 로고
    • Cell death and autophagy under oxidative stress: Roles of poly(ADP-ribose)polymerases and Ca2+
    • Wyrsch, P.; Blenn, C.; Bader, J.; Althaus, F.R. Cell death and autophagy under oxidative stress: Roles of poly(ADP-ribose)polymerases and Ca2+. Mol. Cell Biol. 2012, 32, 3541-3553.
    • (2012) Mol. Cell Biol , vol.32 , pp. 3541-3553
    • Wyrsch, P.1    Blenn, C.2    Bader, J.3    Althaus, F.R.4
  • 40
    • 84866155363 scopus 로고    scopus 로고
    • Neuronal autophagy: A housekeeper or a fighter in neuronal cell survival
    • Lee, J.A. Neuronal autophagy: A housekeeper or a fighter in neuronal cell survival? Exp. Neurobiol. 2012, 21, 1-8.
    • (2012) Exp. Neurobiol , vol.21 , pp. 1-8
    • Lee, J.A.1
  • 41
    • 82155162775 scopus 로고    scopus 로고
    • Autophagic activity in cortical neurons under acute oxidative stress directly contributes to cell death
    • Higgins, G.C.; Devenish, R.J.; Beart, P.M.; Nagley, P. Autophagic activity in cortical neurons under acute oxidative stress directly contributes to cell death. Cell. Mol. Life Sci. 2011, 68, 3725-3740.
    • (2011) Cell. Mol. Life Sci , vol.68 , pp. 3725-3740
    • Higgins, G.C.1    Devenish, R.J.2    Beart, P.M.3    Nagley, P.4
  • 43
    • 67650727404 scopus 로고    scopus 로고
    • Oxidative stress induces parallel autophagy and mitochondria dysfunction in human glioma U251 cells
    • Zhang, H.; Kong, X.; Kang, J.; Su, J.; Li, Y.; Zhong, J.; Sun, L. Oxidative stress induces parallel autophagy and mitochondria dysfunction in human glioma U251 cells. Toxicol. Sci. 2009, 110, 376-388.
    • (2009) Toxicol. Sci , vol.110 , pp. 376-388
    • Zhang, H.1    Kong, X.2    Kang, J.3    Su, J.4    Li, Y.5    Zhong, J.6    Sun, L.7
  • 45
    • 79953156939 scopus 로고    scopus 로고
    • Loss of caspase-2-dependent apoptosis induces autophagy after mitochondrial oxidative stress in primary cultures of young adult cortical neurons
    • Tiwari, M.; Lopez-Cruzan, M.; Morgan, W.W.; Herman, B. Loss of caspase-2-dependent apoptosis induces autophagy after mitochondrial oxidative stress in primary cultures of young adult cortical neurons. J. Biol. Chem. 2011, 286, 8493-8506.
    • (2011) J. Biol. Chem , vol.286 , pp. 8493-8506
    • Tiwari, M.1    Lopez-Cruzan, M.2    Morgan, W.W.3    Herman, B.4
  • 48
    • 78649636176 scopus 로고    scopus 로고
    • Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria
    • Wirawan, E.; Vande Walle, L.; Kersse, K.; Cornelis, S.; Claerhout, S.; Vanoverberghe, I.; Roelandt, R.; de Rycke, R.; Verspurten, J.; Declercq, W.; et al. Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria. Cell Death Dis. 2010, 1, e18.
    • (2010) Cell Death Dis , vol.1
    • Wirawan, E.1    Vande, W.L.2    Kersse, K.3    Cornelis, S.4    Claerhout, S.5    Vanoverberghe, I.6    Roelandt, R.7    de Rycke, R.8    Verspurten, J.9    Declercq, W.10
  • 51
    • 79953230490 scopus 로고    scopus 로고
    • Beclin 1 cleavage by caspase-3 inactivates autophagy and promotes apoptosis
    • Zhu, Y.; Zhao, L.; Liu, L.; Gao, P.; Tian, W.; Wang, X.; Jin, H.; Xu, H.; Chen, Q. Beclin 1 cleavage by caspase-3 inactivates autophagy and promotes apoptosis. Protein Cell 2010, 1, 468-477.
    • (2010) Protein Cell , vol.1 , pp. 468-477
    • Zhu, Y.1    Zhao, L.2    Liu, L.3    Gao, P.4    Tian, W.5    Wang, X.6    Jin, H.7    Xu, H.8    Chen, Q.9
  • 52
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak, K.J.; Schmittgen, T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001, 25, 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.