Evaluation of riproximin binding properties reveals a novel mechanism for cellular targeting

Journal of Biological Chemistry

Volumn 287, Issue 43, 2012, Pages 35873-35886

  Bayer, Helene ^a   Essig, Katharina ^a   Stanzel, Sven ^a   Frank, Martin ^b   Gildersleeve, Jeffrey C ^c   Berger, Martin R ^a   Voss, Cristina ^d  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b BIOGNOS AB   (Sweden)

^c NATIONAL CANCER INSTITUTE   (United States)

^d Wilex Biotechnology GmbH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ASIALOFETUIN; BINDING INTERACTION; BINDING PROPERTIES; BINDING SPECIFICITIES; BIOLOGICAL IMPLICATIONS; CARBOHYDRATE MICROARRAYS; CELL SURFACES; CELLULAR ASSAYS; CROSS-LINKING ABILITY; CROSSLINKS; CYTOTOXIC; DEGREE OF SPECIFICITY; GLYCANS; GLYCOCONJUGATES; HIGH SELECTIVITY; MODEL PROTEINS; N-ACETYL-D-GALACTOSAMINE; N-GLYCAN STRUCTURES; ON DYNAMICS; RIBOSOME-INACTIVATING PROTEIN; SUGAR BINDING; TUMOR CELL LINES; TYPE II;

BINDING ENERGY; CARBOHYDRATES; CELL CULTURE; CELL MEMBRANES; DISEASES; GLYCOPROTEINS; PROTEINS;

CYTOTOXICITY;

ASIALO BOVINE SUBMAXILLARY MUCIN; ASIALOFETUIN; BIANTENNARY COMPLEX N GLYCAN; GLYCAN; GLYCOCONJUGATE; MUCIN; N ACETYLGALACTOSAMINE; RIBOSOME INACTIVATING PROTEIN; RIPROXIMIN; TN ANTIGEN; TRIANTENNARY COMPLEX N GLYCAN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING COMPETITION; BINDING SITE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG MECHANISM; DRUG SPECIFICITY; ENZYME LINKED IMMUNOSORBENT ASSAY; LECTIN BINDING; MICROARRAY ANALYSIS; PRIORITY JOURNAL; PROTEIN CROSS LINKING; TUMOR CELL;

ANIMALS; BINDING SITES; CATTLE; CYTOTOXINS; DRUG DELIVERY SYSTEMS; HELA CELLS; HUMANS; MUCINS; OLACACEAE; PLANT PROTEINS; PROTEIN BINDING;

EID: 84867753157     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.368548     Document Type: Article

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