Suppression of human T cell proliferation by the caspase inhibitors, z-VAD-FMK and z-IETD-FMK is independent of their caspase inhibition properties

Toxicology and Applied Pharmacology

Volumn 265, Issue 1, 2012, Pages 103-112

  Lawrence, C P ^a   Chow, S C ^b  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b MONASH UNIVERSITY MALAYSIA   (Malaysia)

Author keywords

Caspases; T cell activation; T lymphocytes; Z IETD FMK; Z VAD FMK

Indexed keywords

BENZYLOXYCARBONYL VALYL ALANYL ASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLISOLEUCYLGLUTAMYLTHREONYLASPARTYL FLUOROMETHYL KETONE; CASPASE 3; CASPASE 8; CASPASE INHIBITOR; CD69 ANTIGEN; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; MITOGENIC AGENT; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME INHIBITION; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; IN VITRO STUDY; LEUKEMIA CELL LINE; NORMAL HUMAN; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

AMINO ACID CHLOROMETHYL KETONES; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CASPASE 8; CASPASE INHIBITORS; CELL PROLIFERATION; CELL SEPARATION; EIF-2 KINASE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INDICATORS AND REAGENTS; INTERFERON-GAMMA; INTERLEUKIN-2; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; LECTINS, C-TYPE; LYMPHOCYTE ACTIVATION; MITOGENS; NF-KAPPA B; OLIGOPEPTIDES; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TRANSLOCATION, GENETIC;

EID: 84867740775     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2012.09.002     Document Type: Article

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