Effects of gemfibrozil on lipid metabolism, steroidogenesis, and reproduction in the fathead minnow (Pimephales promelas)

Environmental Toxicology and Chemistry

Volumn 31, Issue 11, 2012, Pages 2615-2624

  Skolness, Sarah Y ^a   Durhan, Elizabeth J ^b   Jensen, Kathleen M ^b   Kahl, Michael D ^b   Makynen, Elizabeth A ^b   Villeneuve, Daniel L ^b   Ankley, Gerald T ^b  

^a UNIVERSITY OF MINNESOTA DULUTH   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Aromatase; Cholesterol; Fish; Pharmaceutical; Toxicity

Indexed keywords

AROMATASE; FATHEAD MINNOW; FIBRATES; GEMFIBROZILS; HEPATIC GENES; LIPID METABOLISMS; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR; PIMEPHALES PROMELAS; PLASMA CHOLESTEROL; POTENTIAL IMPACTS; SEX STEROIDS; SHORT-TERM TEST; WASTEWATER TREATMENT PLANTS; WATER CONCENTRATIONS;

BIOCHEMISTRY; CHOLESTEROL; CYTOLOGY; DRUG PRODUCTS; EFFLUENTS; FISH; GENE EXPRESSION; METABOLISM; TOXICITY;

PHYSIOLOGY;

CHOLESTEROL; CYTOCHROME P450 1A1; CYTOCHROME P450 3A; GEMFIBROZIL; SEX HORMONE; TRIACYLGLYCEROL;

CYPRINID; DRINKING WATER; DRUG; EFFLUENT; ENZYME ACTIVITY; FECUNDITY; FISH; GENE EXPRESSION; LIPID; METABOLISM; PHYSIOLOGICAL RESPONSE; POLLUTION EXPOSURE; SAMPLING; WASTE TREATMENT; WASTEWATER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DRUG EFFECT; DRUG EXPOSURE; DRUG TISSUE LEVEL; FEMALE; FERTILITY; GENE EXPRESSION; LIPID METABOLISM; MALE; NONHUMAN; PIMEPHALES PROMELAS; PRIORITY JOURNAL; REPRODUCTION; STEROIDOGENESIS; TRIACYLGLYCEROL BLOOD LEVEL;

ANIMALS; CYPRINIDAE; FEMALE; FERTILITY; GEMFIBROZIL; LIPID METABOLISM; LIVER; MALE; REPRODUCTION; STEROIDS; TOXICITY TESTS, ACUTE; TOXICITY TESTS, SUBACUTE; WATER POLLUTANTS, CHEMICAL;

PIMEPHALES PROMELAS;

EID: 84867732351     PISSN: 07307268     EISSN: 15528618     Source Type: Journal    
DOI: 10.1002/etc.1989     Document Type: Article

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