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Volumn 8, Issue 4, 2012, Pages 373-379

The effect of the postmortem interval on the redistribution of drugs: A comparison of mortuary admission and autopsy blood specimens

Author keywords

Femoral blood; Forensic autopsy; Heart blood; Postmortem interval; Postmortem redistribution; Toxicology

Indexed keywords


EID: 84867635996     PISSN: 1547769X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12024-012-9341-2     Document Type: Article
Times cited : (101)

References (64)
  • 1
    • 0036128470 scopus 로고    scopus 로고
    • Postmortem drug analysis: analytical and toxicological aspects
    • Drummer OH, Gerostamoulos J. Postmortem drug analysis: analytical and toxicological aspects. Ther Drug Monit. 2002; 24(2): 199-209.
    • (2002) Ther Drug Monit , vol.24 , Issue.2 , pp. 199-209
    • Drummer, O.H.1    Gerostamoulos, J.2
  • 2
    • 23044504753 scopus 로고    scopus 로고
    • Key concepts in postmortem drug redistribution
    • Yarema MC, Becker CE. Key concepts in postmortem drug redistribution. Clin Toxicol (Phila). 2005; 43(4): 235-41.
    • (2005) Clin Toxicol (Phila) , vol.43 , Issue.4 , pp. 235-241
    • Yarema, M.C.1    Becker, C.E.2
  • 3
    • 49649100492 scopus 로고    scopus 로고
    • Postmortem clinical pharmacology
    • Ferner RE. Postmortem clinical pharmacology. Br J Clin Pharmacol. 2008; 66(4): 430-43.
    • (2008) Br J Clin Pharmacol , vol.66 , Issue.4 , pp. 430-443
    • Ferner, R.E.1
  • 5
    • 77956876794 scopus 로고    scopus 로고
    • Postmortem toxicology
    • Skopp G. Postmortem toxicology. Forensic Sci Med Pathol. 2010; 6(4): 314-25.
    • (2010) Forensic Sci Med Pathol , vol.6 , Issue.4 , pp. 314-325
    • Skopp, G.1
  • 6
    • 0023216461 scopus 로고
    • Site dependence of drug concentrations in postmortem blood-a case study
    • Jones GR, Pounder DJ. Site dependence of drug concentrations in postmortem blood-a case study. J Anal Toxicol. 1987; 11(5): 186-90.
    • (1987) J Anal Toxicol , vol.11 , Issue.5 , pp. 186-190
    • Jones, G.R.1    Pounder, D.J.2
  • 7
    • 0023259797 scopus 로고
    • A comparison of postmortem heart blood and femoral blood ethyl alcohol concentrations
    • Prouty RW, Anderson WH. A comparison of postmortem heart blood and femoral blood ethyl alcohol concentrations. J Anal Toxicol. 1987; 11(5): 191-7.
    • (1987) J Anal Toxicol , vol.11 , Issue.5 , pp. 191-197
    • Prouty, R.W.1    Anderson, W.H.2
  • 9
    • 0028107430 scopus 로고
    • Postmortem release of amitriptyline from the lungs; a mechanism of postmortem drug redistribution
    • Hilberg T, Mørland J, Bjørneboe A. Postmortem release of amitriptyline from the lungs; a mechanism of postmortem drug redistribution. Forensic Sci Int. 1994; 64(1): 47-55.
    • (1994) Forensic Sci Int , vol.64 , Issue.1 , pp. 47-55
    • Hilberg, T.1    Mørland, J.2    Bjørneboe, A.3
  • 10
    • 0028672545 scopus 로고
    • Postmortem clomipramine: therapeutic or toxic concentrations?
    • McIntyre IM, King CV, Cordner SM, Drummer OH. Postmortem clomipramine: therapeutic or toxic concentrations? J Forensic Sci. 1994; 39(2): 486-93.
    • (1994) J Forensic Sci , vol.39 , Issue.2 , pp. 486-493
    • McIntyre, I.M.1    King, C.V.2    Cordner, S.M.3    Drummer, O.H.4
  • 11
    • 0028001080 scopus 로고
    • Postmortem redistribution and degradation of dothiepin: human case studies and an animal model
    • Pounder DJ, Hartley AK, Watmough PJ. Postmortem redistribution and degradation of dothiepin: human case studies and an animal model. Am J Forensic Med Pathol. 1994; 15(3): 231-5.
    • (1994) Am J Forensic Med Pathol , vol.15 , Issue.3 , pp. 231-235
    • Pounder, D.J.1    Hartley, A.K.2    Watmough, P.J.3
  • 12
    • 0029967629 scopus 로고    scopus 로고
    • Postmortem distribution and redistribution of morphine in man
    • Logan BK, Smirnow D. Postmortem distribution and redistribution of morphine in man. J Forensic Sci. 1996; 41(2): 221-9.
    • (1996) J Forensic Sci , vol.41 , Issue.2 , pp. 221-229
    • Logan, B.K.1    Smirnow, D.2
  • 13
    • 0030931030 scopus 로고    scopus 로고
    • Postmortem serum and tissue redistribution of fluoxetine and norfluoxetine in dogs following oral administration of fluoxetine hydrochloride (Prozac®)
    • Pohland RC, Bernhard NR. Postmortem serum and tissue redistribution of fluoxetine and norfluoxetine in dogs following oral administration of fluoxetine hydrochloride (Prozac®). J Forensic Sci. 1997; 42(5): 812-6.
    • (1997) J Forensic Sci , vol.42 , Issue.5 , pp. 812-816
    • Pohland, R.C.1    Bernhard, N.R.2
  • 14
    • 0031929712 scopus 로고    scopus 로고
    • Postmortem distribution and redistribution of nitrobenzodiazepines in man
    • Robertson MD, Drummer OH. Postmortem distribution and redistribution of nitrobenzodiazepines in man. J Forensic Sci. 1998; 43(1): 9-13.
    • (1998) J Forensic Sci , vol.43 , Issue.1 , pp. 9-13
    • Robertson, M.D.1    Drummer, O.H.2
  • 15
    • 0032810848 scopus 로고    scopus 로고
    • Methamphetamine-a study of postmortem redistribution
    • Barnhart FE, Fogacci JR, Reed DW. Methamphetamine-a study of postmortem redistribution. J Anal Toxicol. 1999; 23(1): 69-70.
    • (1999) J Anal Toxicol , vol.23 , Issue.1 , pp. 69-70
    • Barnhart, F.E.1    Fogacci, J.R.2    Reed, D.W.3
  • 16
    • 0032898590 scopus 로고    scopus 로고
    • Postmortem stability and interpretation of β2-agonist concentrations
    • Couper FJ, Drummer OH. Postmortem stability and interpretation of β2-agonist concentrations. J Forensic Sci. 1999; 44(3): 523-6.
    • (1999) J Forensic Sci , vol.44 , Issue.3 , pp. 523-526
    • Couper, F.J.1    Drummer, O.H.2
  • 17
    • 0032956707 scopus 로고    scopus 로고
    • A study involving venlafaxine overdoses: comparison of fatal and therapeutic concentrations in postmortem specimens
    • Jaffe PD, Batziris HP, van der Hoeven P, et al. A study involving venlafaxine overdoses: comparison of fatal and therapeutic concentrations in postmortem specimens. J Forensic Sci. 1999; 44(1): 193-6.
    • (1999) J Forensic Sci , vol.44 , Issue.1 , pp. 193-196
    • Jaffe, P.D.1    Batziris, H.P.2    van der Hoeven, P.3
  • 19
    • 0033920403 scopus 로고    scopus 로고
    • Postmortem redistribution of morphine and its metabolites
    • Gerostamoulos J, Drummer OH. Postmortem redistribution of morphine and its metabolites. J Forensic Sci. 2000; 45(4): 843-5.
    • (2000) J Forensic Sci , vol.45 , Issue.4 , pp. 843-845
    • Gerostamoulos, J.1    Drummer, O.H.2
  • 20
    • 0037223819 scopus 로고    scopus 로고
    • Clozapine and postmortem redistribution
    • Kerswill RM, Vicente MR. Clozapine and postmortem redistribution. Am J Psychiatry. 2003; 160(1): 184.
    • (2003) Am J Psychiatry , vol.160 , Issue.1 , pp. 184
    • Kerswill, R.M.1    Vicente, M.R.2
  • 21
    • 33750519655 scopus 로고    scopus 로고
    • The redistribution of selected psychiatric drugs in postmortem cases
    • Rodda KE, Drummer OH. The redistribution of selected psychiatric drugs in postmortem cases. Forensic Sci Int. 2006; 164(2-3): 235-9.
    • (2006) Forensic Sci Int , vol.164 , Issue.2-3 , pp. 235-239
    • Rodda, K.E.1    Drummer, O.H.2
  • 23
    • 0002015018 scopus 로고    scopus 로고
    • Pericardial fluid as an alternative specimen to blood for postmortem toxicological analyses
    • Moriya F, Hashimoto Y. Pericardial fluid as an alternative specimen to blood for postmortem toxicological analyses. Legal Med. 1999; 1(2): 86-94.
    • (1999) Legal Med , vol.1 , Issue.2 , pp. 86-94
    • Moriya, F.1    Hashimoto, Y.2
  • 24
    • 0032946353 scopus 로고    scopus 로고
    • Redistribution of basic drugs into cardiac blood from surrounding tissues during early-stages postmortem
    • Moriya F, Hashimoto Y. Redistribution of basic drugs into cardiac blood from surrounding tissues during early-stages postmortem. J Forensic Sci. 1999; 44(1): 10-6.
    • (1999) J Forensic Sci , vol.44 , Issue.1 , pp. 10-16
    • Moriya, F.1    Hashimoto, Y.2
  • 25
    • 23044504753 scopus 로고    scopus 로고
    • Key concepts in postmortem drug redistribution
    • Yarema MC, Becker CE. Key concepts in postmortem drug redistribution. Clin Toxicol. 2005; 43(4): 235-41.
    • (2005) Clin Toxicol , vol.43 , Issue.4 , pp. 235-241
    • Yarema, M.C.1    Becker, C.E.2
  • 28
    • 77950894571 scopus 로고    scopus 로고
    • Forensic toxicology
    • Drummer OH. Forensic toxicology. EXS. 2010; 100: 579-603.
    • (2010) EXS. , vol.100 , pp. 579-603
    • Drummer, O.H.1
  • 29
    • 0025212634 scopus 로고
    • The forensic science implications of site and temporal influences on postmortem blood-drug concentrations
    • Prouty RW, Anderson WH. The forensic science implications of site and temporal influences on postmortem blood-drug concentrations. J Forensic Sci. 1990; 35(2): 243-70.
    • (1990) J Forensic Sci , vol.35 , Issue.2 , pp. 243-270
    • Prouty, R.W.1    Anderson, W.H.2
  • 30
    • 77949284107 scopus 로고    scopus 로고
    • The influence of putrefaction and sample storage on postmortem toxicology results
    • Butzbach DM. The influence of putrefaction and sample storage on postmortem toxicology results. Forensic Sci Med Pathol. 2010; 6(1): 35-45.
    • (2010) Forensic Sci Med Pathol , vol.6 , Issue.1 , pp. 35-45
    • Butzbach, D.M.1
  • 31
    • 0026356468 scopus 로고
    • Site-dependent postmortem changes in blood cocaine concentrations
    • Hearn WL, Keran EE, Huang W, Hime G. Site-dependent postmortem changes in blood cocaine concentrations. J Forensic Sci. 1991; 36(3): 673-84.
    • (1991) J Forensic Sci , vol.36 , Issue.3 , pp. 673-684
    • Hearn, W.L.1    Keran, E.E.2    Huang, W.3    Hime, G.4
  • 32
    • 77955867587 scopus 로고    scopus 로고
    • Identification and quantification of 30 antipsychotics in blood using LC-MS/MS
    • Saar E, Gerostamoulos D, Dummer OH, et al. Identification and quantification of 30 antipsychotics in blood using LC-MS/MS. J Mass Spectrom. 2010; 45(8): 915-25.
    • (2010) J Mass Spectrom , vol.45 , Issue.8 , pp. 915-925
    • Saar, E.1    Gerostamoulos, D.2    Dummer, O.H.3
  • 33
    • 0034026438 scopus 로고    scopus 로고
    • Estimating antemortem drug concentrations from postmortem blood samples: the influence of postmortem redistribution
    • Cook DS, Braithwaite RA, Hale KA. Estimating antemortem drug concentrations from postmortem blood samples: the influence of postmortem redistribution. J Clin Pathol. 2000; 53(4): 282-5.
    • (2000) J Clin Pathol , vol.53 , Issue.4 , pp. 282-285
    • Cook, D.S.1    Braithwaite, R.A.2    Hale, K.A.3
  • 35
    • 0141742605 scopus 로고    scopus 로고
    • Is postmortem toxicology quackery?
    • Karch SB. Is postmortem toxicology quackery? J Clin Forensic Med. 2003; 10(3): 197-8.
    • (2003) J Clin Forensic Med , vol.10 , Issue.3 , pp. 197-198
    • Karch, S.B.1
  • 36
    • 24044469019 scopus 로고    scopus 로고
    • Analytical toxicology: guidelines for sample collection postmortem
    • Flanagan RJ, Connally G, Evans JM. Analytical toxicology: guidelines for sample collection postmortem. Toxicol Rev. 2005; 24(1): 63-71.
    • (2005) Toxicol Rev , vol.24 , Issue.1 , pp. 63-71
    • Flanagan, R.J.1    Connally, G.2    Evans, J.M.3
  • 37
    • 0027263629 scopus 로고
    • ACP Broadsheet no 137: April 1993. Obtaining samples at post mortem examination for toxicological and biochemical analyses
    • Forrest AR. ACP Broadsheet no 137: April 1993. Obtaining samples at post mortem examination for toxicological and biochemical analyses. J Clin Pathol. 1993; 46(4): 292-6.
    • (1993) J Clin Pathol , vol.46 , Issue.4 , pp. 292-296
    • Forrest, A.R.1
  • 38
    • 77949586353 scopus 로고    scopus 로고
    • Postmortem drug concentrations
    • Kennedy MC. Postmortem drug concentrations. Intern Med J. 2010; 40(3): 183-7.
    • (2010) Intern Med J , vol.40 , Issue.3 , pp. 183-187
    • Kennedy, M.C.1
  • 39
    • 77955898529 scopus 로고    scopus 로고
    • Collection of biological samples in forensic toxicology
    • Dinis-Oliveira RJ, Carvalho F, Duarte JA, et al. Collection of biological samples in forensic toxicology. Toxicol Mech Methods. 2010; 20(7): 363-414.
    • (2010) Toxicol Mech Methods , vol.20 , Issue.7 , pp. 363-414
    • Dinis-Oliveira, R.J.1    Carvalho, F.2    Duarte, J.A.3
  • 40
    • 2542507165 scopus 로고    scopus 로고
    • Postmortem toxicology of drugs of abuse
    • Drummer OH. Postmortem toxicology of drugs of abuse. Forensic Sci Int. 2004; 142(2-3): 101-13.
    • (2004) Forensic Sci Int , vol.142 , Issue.2-3 , pp. 101-113
    • Drummer, O.H.1
  • 41
    • 2542503653 scopus 로고    scopus 로고
    • Preanalytic aspects in postmortem toxicology
    • Skopp G. Preanalytic aspects in postmortem toxicology. Forensic Sci Int. 2004; 142(2-3): 75-100.
    • (2004) Forensic Sci Int , vol.142 , Issue.2-3 , pp. 75-100
    • Skopp, G.1
  • 42
    • 33846060715 scopus 로고    scopus 로고
    • Postmortem toxicology
    • Drummer OH. Postmortem toxicology. Forensic Sci Int. 2007; 165(2-3): 199-203.
    • (2007) Forensic Sci Int , vol.165 , Issue.2-3 , pp. 199-203
    • Drummer, O.H.1
  • 44
    • 0024447476 scopus 로고
    • Fluoxetine overdose: a case report
    • Rohrig TP, Prouty RW. Fluoxetine overdose: a case report. J Anal Toxicol. 1989; 13(5): 305-7.
    • (1989) J Anal Toxicol , vol.13 , Issue.5 , pp. 305-307
    • Rohrig, T.P.1    Prouty, R.W.2
  • 45
    • 0024471865 scopus 로고
    • A nortriptyline death with unusually high tissue concentrations
    • Rohrig TP, Prouty RW. A nortriptyline death with unusually high tissue concentrations. J Anal Toxicol. 1989; 13(5): 303-4.
    • (1989) J Anal Toxicol , vol.13 , Issue.5 , pp. 303-304
    • Rohrig, T.P.1    Prouty, R.W.2
  • 46
    • 0032826802 scopus 로고    scopus 로고
    • Distribution of mirtazapine (Remeron) in thirteen postmortem cases
    • Anderson DT, Fritz KL, Muto JJ. Distribution of mirtazapine (Remeron) in thirteen postmortem cases. J Anal Toxicol. 1999; 23(6): 544-8.
    • (1999) J Anal Toxicol , vol.23 , Issue.6 , pp. 544-548
    • Anderson, D.T.1    Fritz, K.L.2    Muto, J.J.3
  • 47
    • 0027994080 scopus 로고
    • Distribution of sertraline in postmortem cases
    • Levine B, Jenkins AJ, Smialek JE. Distribution of sertraline in postmortem cases. J Anal Toxicol. 1994; 18(5): 272-4.
    • (1994) J Anal Toxicol , vol.18 , Issue.5 , pp. 272-274
    • Levine, B.1    Jenkins, A.J.2    Smialek, J.E.3
  • 48
    • 79954578677 scopus 로고    scopus 로고
    • Evaluating the relationship between postmortem and antemortem morphine and codeine concentrations in whole blood
    • Tolliver SSH, Lee W, Furton KG. Evaluating the relationship between postmortem and antemortem morphine and codeine concentrations in whole blood. J Anal Toxicol. 2010; 34: 491-7.
    • (2010) J Anal Toxicol , vol.34 , pp. 491-497
    • Tolliver, S.S.H.1    Lee, W.2    Furton, K.G.3
  • 50
  • 51
    • 70349394903 scopus 로고    scopus 로고
    • Response to postcard from Sweden
    • Karch S. Response to postcard from Sweden. J Forensic Leg Med. 2009; 16(8): 501-2.
    • (2009) J Forensic Leg Med , vol.16 , Issue.8 , pp. 501-502
    • Karch, S.1
  • 52
    • 0033678153 scopus 로고    scopus 로고
    • Morphine-3-d glucuronide stability in postmortem specimens exposed to bacterial enzymatic hydrolysis
    • Carroll FT, Marraccini JV, Lewis S, Wright W. Morphine-3-d glucuronide stability in postmortem specimens exposed to bacterial enzymatic hydrolysis. Am J Forensic Med Pathol. 2000; 21(4): 323-9.
    • (2000) Am J Forensic Med Pathol , vol.21 , Issue.4 , pp. 323-329
    • Carroll, F.T.1    Marraccini, J.V.2    Lewis, S.3    Wright, W.4
  • 53
    • 33645509739 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacokinetic variability of heroin and its metabolites: review of the literature
    • Rook EJ, Huitema ADR, van den Brink W, van Ree JM, Beijnen JH. Pharmacokinetics and pharmacokinetic variability of heroin and its metabolites: review of the literature. Curr Clin Pharmacol. 2006; 1(1): 109-18.
    • (2006) Curr Clin Pharmacol , vol.1 , Issue.1 , pp. 109-118
    • Rook, E.J.1    Huitema, A.D.R.2    van den Brink, W.3    van Ree, J.M.4    Beijnen, J.H.5
  • 54
    • 0038724557 scopus 로고    scopus 로고
    • Screening for and validated quantification of amphetamines and of amphetamine- and piperazine-derived designer drugs in human blood plasma by gas chromatography/mass spectrometry
    • Peters FT, Schaefer S, Staack RF, et al. Screening for and validated quantification of amphetamines and of amphetamine- and piperazine-derived designer drugs in human blood plasma by gas chromatography/mass spectrometry. J Mass Spectrom. 2003; 38(6): 659-76.
    • (2003) J Mass Spectrom , vol.38 , Issue.6 , pp. 659-676
    • Peters, F.T.1    Schaefer, S.2    Staack, R.F.3
  • 55
    • 3142690518 scopus 로고    scopus 로고
    • Stability of drugs in stored postmortem femoral blood and vitreous humor
    • Holmgren P, Druid H, Holmgren A, et al. Stability of drugs in stored postmortem femoral blood and vitreous humor. J Forensic Sci. 2004; 49(4): 820-5.
    • (2004) J Forensic Sci , vol.49 , Issue.4 , pp. 820-825
    • Holmgren, P.1    Druid, H.2    Holmgren, A.3
  • 56
    • 0021750033 scopus 로고
    • The stability of some drugs and poisons in putrefying human liver tissues
    • Stevens HM. The stability of some drugs and poisons in putrefying human liver tissues. J Forensic Sci Soc. 1984; 24(6): 577-89.
    • (1984) J Forensic Sci Soc , vol.24 , Issue.6 , pp. 577-589
    • Stevens, H.M.1
  • 58
    • 0029053844 scopus 로고
    • Postmortem drug metabolism by bacteria
    • Robertson MD, Drummer OH. Postmortem drug metabolism by bacteria. J Forensic Sci. 1995; 40(3): 382-6.
    • (1995) J Forensic Sci , vol.40 , Issue.3 , pp. 382-386
    • Robertson, M.D.1    Drummer, O.H.2
  • 59
    • 67650995779 scopus 로고    scopus 로고
    • Quantitative structure-activity relationship (QSAR) methodology in forensic toxicology: modeling postmortem redistribution of structurally diverse drugs using multivariate statistics
    • Giaginis C, Tsantili-Kakoulidou A, Theocharis S. Quantitative structure-activity relationship (QSAR) methodology in forensic toxicology: modeling postmortem redistribution of structurally diverse drugs using multivariate statistics. Forensic Sci Int. 2009; 190(1-3): 9-15.
    • (2009) Forensic Sci Int , vol.190 , Issue.1-3 , pp. 9-15
    • Giaginis, C.1    Tsantili-Kakoulidou, A.2    Theocharis, S.3
  • 60
    • 0032723024 scopus 로고    scopus 로고
    • Forensic toxicology laboratory guidelines
    • Jones GR, Peat MA. Forensic toxicology laboratory guidelines. J Anal Toxicol. 1999; 23(7): 636.
    • (1999) J Anal Toxicol , vol.23 , Issue.7 , pp. 636
    • Jones, G.R.1    Peat, M.A.2
  • 61
    • 56449085723 scopus 로고    scopus 로고
    • Comparison of drug concentrations taken from clamped and unclamped femoral vessels
    • Hargrove VM, McCutcheon JR. Comparison of drug concentrations taken from clamped and unclamped femoral vessels. J Anal Toxicol. 2008; 32(8): 621-5.
    • (2008) J Anal Toxicol , vol.32 , Issue.8 , pp. 621-625
    • Hargrove, V.M.1    McCutcheon, J.R.2
  • 62
    • 0026661550 scopus 로고
    • Diffusion as a mechanism of postmortem drug redistribution: an experimental study in rats
    • Hilberg T, Bugge A, Beylich KM, Mørland J, Bjørneboe A. Diffusion as a mechanism of postmortem drug redistribution: an experimental study in rats. Int J Legal Med. 1992; 105(2): 87-91.
    • (1992) Int J Legal Med , vol.105 , Issue.2 , pp. 87-91
    • Hilberg, T.1    Bugge, A.2    Beylich, K.M.3    Mørland, J.4    Bjørneboe, A.5
  • 63
    • 0036903401 scopus 로고    scopus 로고
    • Methadone dose and postmortem blood concentration
    • Caplehorn JR, Drummer OH. Methadone dose and postmortem blood concentration. Drug Alcohol Rev. 2002; 21(4): 329-33.
    • (2002) Drug Alcohol Rev , vol.21 , Issue.4 , pp. 329-333
    • Caplehorn, J.R.1    Drummer, O.H.2


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