Morphine-3-D glucuronide stability in postmortem specimens exposed to bacterial enzymatic hydrolysis

American Journal of Forensic Medicine and Pathology

Volumn 21, Issue 4, 2000, Pages 323-329

  Carroll, F Thomas ^a,b   Marraccini, John V ^b   Lewis, Susan ^a   Wright, William ^a  

^a Palm Beach County Sheriff's Office   (United States)

^b NONE   (United States)

Author keywords

Enzymatic hydrolysis; Forensic science; Glucuronidase; Heroin; Morphine; Morphine 3 D glucuronide (M3DG); Postmortem stability; Putrefaction

Indexed keywords

MORPHINE 3 GLUCURONIDE;

ARTICLE; AUTOPSY; DRUG DETERMINATION; DRUG STABILITY; ENZYME ACTIVITY; HYDROLYSIS; SAMPLING;

ADOLESCENT; AGED; ANIMALS; BACTERIA; CATTLE; FEMALE; FORENSIC MEDICINE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GLUCURONIDASE; HUMANS; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; INDICATORS AND REAGENTS; INTESTINES; MALE; MIDDLE AGED; MORPHINE; MORPHINE DERIVATIVES; POSTMORTEM CHANGES; PRESERVATIVES, PHARMACEUTICAL; SODIUM FLUORIDE; SPECIMEN HANDLING; TEMPERATURE; TIME FACTORS;

EID: 0033678153     PISSN: 01957910     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000433-200012000-00005     Document Type: Article

References (7)

1. Bacterial transmigration as an indication of the time of death
2. Post-mortem drug metabolism by bacteria
3. Unconjugated morphine in blood by radioimmunoassay and gas chromatography/mass spectrometry
4. Simultaneous analysis of codeine, morphine and heroin after β-glucuronidase hydrolysis
5. Hydrolysis of morphine glucuronide
6. Distribution of morphine in body fluids and tissues in fatal overdoses