Atrazine acts as an endocrine disrupter by inhibiting cAMP-specific phosphodiesterase-4

Toxicology and Applied Pharmacology

Volumn 265, Issue 1, 2012, Pages 19-26

  Kucka, Marek ^a   Pogrmic Majkic, Kristina ^b   Fa, Svetlana ^b   Stojilkovic, Stanko S ^a   Kovacevic, Radmila ^b  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b UNIVERSITY OF NOVI SAD   (Serbia)

Author keywords

Atrazine; CAMP specific phosphodiesterases; Endocrine disrupters; Leydig cells; Pituitary cells

Indexed keywords

3 BUTYL 1 METHYLXANTHINE; ATRAZINE; CYCLIC AMP; ENDOCRINE DISRUPTOR; FORSKOLIN; ISOPROTEIN; MESSENGER RNA; PHOSPHODIESTERASE IV INHIBITOR; PROBENECID; ROLIPRAM;

ANDROGEN SYNTHESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL IMMORTALIZATION; CELL TYPE; CONTROLLED STUDY; EXOCYTOSIS; FEMALE; GROWTH HORMONE SECRETING CELL; HORMONE SYNTHESIS; HYPOPHYSIS CELL; LEYDIG CELL; NONHUMAN; PROLACTIN RELEASE; PROTEIN EXPRESSION; RAT;

3',5'-CYCLIC-AMP PHOSPHODIESTERASES; ADENYLATE CYCLASE; ANDROGENS; ANIMALS; ATRAZINE; CELLS, CULTURED; CHORIONIC GONADOTROPIN; CYCLIC AMP; ENDOCRINE DISRUPTORS; EXOCYTOSIS; HERBICIDES; LEYDIG CELLS; MALE; PITUITARY GLAND, ANTERIOR; POLYMERASE CHAIN REACTION; PROLACTIN; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; ROLIPRAM; SIGNAL TRANSDUCTION;

RATTUS;

EID: 84867632847     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2012.09.019     Document Type: Article

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