Nonoisotopic assay for the presynaptic choline transporter reveals capacity for allosteric modulation of choline uptake

ACS Chemical Neuroscience

Volumn 3, Issue 10, 2012, Pages 767-781

  Ruggiero, Alicia M ^a   Wright, Jane ^a   Ferguson, Shawn M ^a   Lewis, Michelle ^a   Emerson, Katie S ^a   Iwamoto, Hideki ^a   Ivy, Michael T ^c   Holmstrand, Ericka C ^a   Ennis, Elizabeth A ^a   Weaver, C David ^a   Blakely, Randy D ^a,b  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^c TENNESSEE STATE UNIVERSITY   (United States)

Author keywords

allosterism; assay; Choline; electrogenic; hemicholinium 3; transporter; uptake

Indexed keywords

HEMICHOLINIUM 3; STAUROSPORINE;

ALLOSTERISM; ARTICLE; ASSAY; CARBOXY TERMINAL SEQUENCE; CELL STRAIN HEK293; CHOLINE UPTAKE; CHOLINERGIC ACTIVITY; CHOLINERGIC TRANSMISSION; CONTROLLED STUDY; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; MEMBRANE DEPOLARIZATION; NERVE ENDING; NONOISOTOPIC ASSAY; PRESYNAPTIC POTENTIAL; PRIORITY JOURNAL; STEADY STATE; SYNAPSE VESICLE;

ALLOSTERIC REGULATION; ANIMALS; CERCOPITHECUS AETHIOPS; CHOLINE; COS CELLS; FEMALE; HEK293 CELLS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; MEMBRANE TRANSPORT PROTEINS; PRESYNAPTIC TERMINALS; PROTEIN TRANSPORT; XENOPUS LAEVIS;

EID: 84867628567     PISSN: None     EISSN: 19487193     Source Type: Journal    
DOI: 10.1021/cn3000718     Document Type: Article

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