Rapid activation of FAK/mTOR/p70S6K/PAK1-signaling controls the early testosterone-induced actin reorganization in colon cancer cells

Cellular Signalling

Volumn 25, Issue 1, 2013, Pages 66-73

  Gu, Shuchen ^a   Kounenidakis, Michalis ^b   Schmidt, Eva Maria ^a   Deshpande, Divija ^a   Alkahtani, Saad ^c   Alarifi, Saud ^d   Föller, Michael ^a,e   Alevizopoulos, Konstantinos ^b   Lang, Florian ^a   Stournaras, Christos ^a,b  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITY OF CRETE   (Greece)

^c KING SAUD UNIVERSITY   (Saudi Arabia)

^d KING SAUD UNIVERSITY   (Saudi Arabia)

^e PRINCESS MARGARET HOSPITAL   (Canada)

Author keywords

Actin reorganization; Actin signaling; Membrane androgen receptors

Indexed keywords

ANDROGEN RECEPTOR; FOCAL ADHESION KINASE; MAMMALIAN TARGET OF RAPAMYCIN; P21 ACTIVATED KINASE 1; S6 KINASE; SMALL INTERFERING RNA; TESTOSTERONE;

ACTIN FILAMENT; ACTIN POLYMERIZATION; ARTICLE; CANCER CELL; CELL ACTIVATION; COLON CANCER; CONCENTRATION RESPONSE; CONTROLLED STUDY; GENE SILENCING; GENE TARGETING; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION;

ACTIN CYTOSKELETON; ACTINS; ANDROGEN RECEPTOR ANTAGONISTS; CACO-2 CELLS; COLONIC NEOPLASMS; FLUTAMIDE; FOCAL ADHESION PROTEIN-TYROSINE KINASES; HUMANS; P21-ACTIVATED KINASES; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; RECEPTORS, ANDROGEN; RHO-ASSOCIATED KINASES; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; RNA INTERFERENCE; RNA, SMALL INTERFERING; SERUM ALBUMIN; SIGNAL TRANSDUCTION; TESTOSTERONE; TOR SERINE-THREONINE KINASES;

MAMMALIA;

EID: 84867625987     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2012.08.005     Document Type: Article

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