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Volumn 314, Issue 17, 2008, Pages 3162-3174

Rho/ROCK/actin signaling regulates membrane androgen receptor induced apoptosis in prostate cancer cells

Author keywords

Actin dynamics; Apoptosis; mAR activation; Prostate cancer; Rho GTPase signaling

Indexed keywords

ACTIN; ACTIN DEPOLYMERIZING FACTOR; ANDROGEN RECEPTOR; BOVINE SERUM ALBUMIN; HORMONE RECEPTOR BLOCKING AGENT; LIM DOMAIN KINASE 2; LIM PROTEIN; MEMBRANE RECEPTOR; PROTEIN CDC42; PROTEIN KINASE; PROTEIN KINASE INHIBITOR; RHO ASSOCIATED COILED COIL CONTAINING PROTEIN KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; RHOB GUANINE NUCLEOTIDE BINDING PROTEIN; TESTOSTERONE; UNCLASSIFIED DRUG;

EID: 53249107178     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2008.07.012     Document Type: Article
Times cited : (59)

References (50)
  • 1
    • 0024545638 scopus 로고
    • Gene regulation by steroid hormones
    • Beato M. Gene regulation by steroid hormones. Cell 56 (1989) 335-344
    • (1989) Cell , vol.56 , pp. 335-344
    • Beato, M.1
  • 2
    • 0034457060 scopus 로고    scopus 로고
    • Mannheim classification of nongenomically initiated (rapid) steroid action(s)
    • Falkenstein E., Norman A.W., and Wehling M. Mannheim classification of nongenomically initiated (rapid) steroid action(s). J. Clin. Endocrinol. Metab. 85 (2000) 2072-2075
    • (2000) J. Clin. Endocrinol. Metab. , vol.85 , pp. 2072-2075
    • Falkenstein, E.1    Norman, A.W.2    Wehling, M.3
  • 3
    • 0029847569 scopus 로고    scopus 로고
    • Dexamethasone alters rapidly actin polymerization dynamics in human endometrial cells: evidence for nongenomic actions involving cAMP turnover
    • Koukouritaki S.B., Theodoropoulos P., Margioris A.N., Gravanis A., and Stournaras C. Dexamethasone alters rapidly actin polymerization dynamics in human endometrial cells: evidence for nongenomic actions involving cAMP turnover. J. Cell. Biochem. 62 (1996) 251-261
    • (1996) J. Cell. Biochem. , vol.62 , pp. 251-261
    • Koukouritaki, S.B.1    Theodoropoulos, P.2    Margioris, A.N.3    Gravanis, A.4    Stournaras, C.5
  • 4
    • 0033276623 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of focal adhesion kinase and paxillin regulates the signaling mechanism of the rapid nongenomic action of dexamethasone on actin cytoskeleton
    • Koukouritaki S.B., Gravanis A., and Stournaras C. Tyrosine phosphorylation of focal adhesion kinase and paxillin regulates the signaling mechanism of the rapid nongenomic action of dexamethasone on actin cytoskeleton. Mol. Med. 5 (1999) 731-742
    • (1999) Mol. Med. , vol.5 , pp. 731-742
    • Koukouritaki, S.B.1    Gravanis, A.2    Stournaras, C.3
  • 5
    • 0032806229 scopus 로고    scopus 로고
    • Immunoaffinity isolation of native membrane glucocorticoid receptor from S-49++ lymphoma cells: biochemical characterization and interaction with Hsp 70 and Hsp 90
    • Powell C.E., Watson C.S., and Gametchu B. Immunoaffinity isolation of native membrane glucocorticoid receptor from S-49++ lymphoma cells: biochemical characterization and interaction with Hsp 70 and Hsp 90. Endocrine 10 (1999) 271-280
    • (1999) Endocrine , vol.10 , pp. 271-280
    • Powell, C.E.1    Watson, C.S.2    Gametchu, B.3
  • 6
    • 0034176552 scopus 로고    scopus 로고
    • Partial purification and biochemical characterization of a membrane glucocorticoid receptor from an amphibian brain
    • Evans S.J., Murray T.F., and Moore F.L. Partial purification and biochemical characterization of a membrane glucocorticoid receptor from an amphibian brain. J. Steroid Biochem. Mol. Biol. 72 (2000) 209-221
    • (2000) J. Steroid Biochem. Mol. Biol. , vol.72 , pp. 209-221
    • Evans, S.J.1    Murray, T.F.2    Moore, F.L.3
  • 7
    • 0344885580 scopus 로고    scopus 로고
    • Identification, classification, and partial characterization of genes in humans and other vertebrates homologous to a fish membrane progestin receptor
    • Zhu Y., Bond J., and Thomas P. Identification, classification, and partial characterization of genes in humans and other vertebrates homologous to a fish membrane progestin receptor. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 2237-2242
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 2237-2242
    • Zhu, Y.1    Bond, J.2    Thomas, P.3
  • 8
    • 0344885581 scopus 로고    scopus 로고
    • Cloning, expression, and characterization of a membrane progestin receptor and evidence it is an intermediary in meiotic maturation of fish oocytes
    • Zhu Y., Rice C.D., Pang Y., Pace M., and Thomas P. Cloning, expression, and characterization of a membrane progestin receptor and evidence it is an intermediary in meiotic maturation of fish oocytes. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 2231-2236
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 2231-2236
    • Zhu, Y.1    Rice, C.D.2    Pang, Y.3    Pace, M.4    Thomas, P.5
  • 10
    • 0036137605 scopus 로고    scopus 로고
    • Linkage of rapid estrogen action to MAPK activation by ERalpha-Shc association and Shc pathway activation
    • Song R.X., McPherson R.A., Adam L., Bao Y., Shupnik M., Kumar R., and Santen R.J. Linkage of rapid estrogen action to MAPK activation by ERalpha-Shc association and Shc pathway activation. Mol. Endocrinol. 16 (2002) 116-127
    • (2002) Mol. Endocrinol. , vol.16 , pp. 116-127
    • Song, R.X.1    McPherson, R.A.2    Adam, L.3    Bao, Y.4    Shupnik, M.5    Kumar, R.6    Santen, R.J.7
  • 12
    • 0032830850 scopus 로고    scopus 로고
    • Testosterone signaling through internalizable surface receptors in androgen receptor-free macrophages
    • Benten W.P., Lieberherr M., Stamm O., Wrehlke C., Guo Z., and Wunderlich F. Testosterone signaling through internalizable surface receptors in androgen receptor-free macrophages. Mol. Biol. Cell 10 (1999) 3113-3123
    • (1999) Mol. Biol. Cell , vol.10 , pp. 3113-3123
    • Benten, W.P.1    Lieberherr, M.2    Stamm, O.3    Wrehlke, C.4    Guo, Z.5    Wunderlich, F.6
  • 13
    • 0036717596 scopus 로고    scopus 로고
    • The human prostate cancer cell line LNCaP bears functional membrane testosterone receptors that increase PSA secretion and modify actin cytoskeleton
    • Kampa M., Papakonstanti E.A., Hatzoglou A., Stathopoulos E.N., Stournaras C., and Castanas E. The human prostate cancer cell line LNCaP bears functional membrane testosterone receptors that increase PSA secretion and modify actin cytoskeleton. FASEB J. 16 (2002) 1429-1431
    • (2002) FASEB J. , vol.16 , pp. 1429-1431
    • Kampa, M.1    Papakonstanti, E.A.2    Hatzoglou, A.3    Stathopoulos, E.N.4    Stournaras, C.5    Castanas, E.6
  • 15
    • 0035663215 scopus 로고    scopus 로고
    • The role of neurosteroids and non-genomic effects of progestins and androgens in mediating sexual receptivity of rodents
    • Frye C.A. The role of neurosteroids and non-genomic effects of progestins and androgens in mediating sexual receptivity of rodents. Brain Res. Brain Res. Rev. 37 (2001) 201-222
    • (2001) Brain Res. Brain Res. Rev. , vol.37 , pp. 201-222
    • Frye, C.A.1
  • 16
    • 33244462381 scopus 로고    scopus 로고
    • The sigma1 protein as a target for the non-genomic effects of neuro(active)steroids: molecular, physiological, and behavioral aspects
    • Monnet F.P., and Maurice T. The sigma1 protein as a target for the non-genomic effects of neuro(active)steroids: molecular, physiological, and behavioral aspects. J. Pharmacol. Sci. 100 (2006) 93-118
    • (2006) J. Pharmacol. Sci. , vol.100 , pp. 93-118
    • Monnet, F.P.1    Maurice, T.2
  • 17
    • 32644434198 scopus 로고    scopus 로고
    • Membrane steroid receptor signaling in normal and neoplastic cells
    • Kampa M., and Castanas E. Membrane steroid receptor signaling in normal and neoplastic cells. Mol. Cell. Endocrinol. 246 (2006) 76-82
    • (2006) Mol. Cell. Endocrinol. , vol.246 , pp. 76-82
    • Kampa, M.1    Castanas, E.2
  • 19
    • 0345874610 scopus 로고    scopus 로고
    • Steroid-hormone rapid actions, membrane receptors and a conformational ensemble model
    • Norman A.W., Mizwicki M.T., and Norman D.P. Steroid-hormone rapid actions, membrane receptors and a conformational ensemble model. Nat. Rev. Drug Discov. 3 (2004) 27-41
    • (2004) Nat. Rev. Drug Discov. , vol.3 , pp. 27-41
    • Norman, A.W.1    Mizwicki, M.T.2    Norman, D.P.3
  • 21
    • 0038636338 scopus 로고    scopus 로고
    • A rapid, nongenomic, signaling pathway regulates the actin reorganization induced by activation of membrane testosterone receptors
    • Papakonstanti E.A., Kampa M., Castanas E., and Stournaras C. A rapid, nongenomic, signaling pathway regulates the actin reorganization induced by activation of membrane testosterone receptors. Mol. Endocrinol. 17 (2003) 870-881
    • (2003) Mol. Endocrinol. , vol.17 , pp. 870-881
    • Papakonstanti, E.A.1    Kampa, M.2    Castanas, E.3    Stournaras, C.4
  • 23
    • 34249824292 scopus 로고    scopus 로고
    • Activation of a membrane-associated androgen receptor promotes cell death in primary cortical astrocytes
    • Gatson J.W., and Singh M. Activation of a membrane-associated androgen receptor promotes cell death in primary cortical astrocytes. Endocrinology 148 (2007) 2458-2464
    • (2007) Endocrinology , vol.148 , pp. 2458-2464
    • Gatson, J.W.1    Singh, M.2
  • 24
    • 33646417329 scopus 로고    scopus 로고
    • DU-145 and PC-3 human prostate cancer cell lines express androgen receptor: implications for the androgen receptor functions and regulation
    • Alimirah F., Chen J., Basrawala Z., Xin H., and Choubey D. DU-145 and PC-3 human prostate cancer cell lines express androgen receptor: implications for the androgen receptor functions and regulation. FEBS Lett. 580 (2006) 2294-2300
    • (2006) FEBS Lett. , vol.580 , pp. 2294-2300
    • Alimirah, F.1    Chen, J.2    Basrawala, Z.3    Xin, H.4    Choubey, D.5
  • 26
    • 0344626940 scopus 로고    scopus 로고
    • Phenotypic and genotypic characterization of commonly used human prostatic cell lines
    • Mitchell S., Abel P., Ware M., Stamp G., and Lalani E. Phenotypic and genotypic characterization of commonly used human prostatic cell lines. BJU Int. 85 (2000) 932-944
    • (2000) BJU Int. , vol.85 , pp. 932-944
    • Mitchell, S.1    Abel, P.2    Ware, M.3    Stamp, G.4    Lalani, E.5
  • 27
    • 15744394838 scopus 로고    scopus 로고
    • LIM-kinase 2 and cofilin phosphorylation mediate actin cytoskeleton reorganization induced by transforming growth factor-beta
    • Vardouli L., Moustakas A., and Stournaras C. LIM-kinase 2 and cofilin phosphorylation mediate actin cytoskeleton reorganization induced by transforming growth factor-beta. J. Biol. Chem. 280 (2005) 11448-11457
    • (2005) J. Biol. Chem. , vol.280 , pp. 11448-11457
    • Vardouli, L.1    Moustakas, A.2    Stournaras, C.3
  • 28
    • 1542283796 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha promotes survival of opossum kidney cells via Cdc42-induced phospholipase C-gamma1 activation and actin filament redistribution
    • Papakonstanti E.A., and Stournaras C. Tumor necrosis factor-alpha promotes survival of opossum kidney cells via Cdc42-induced phospholipase C-gamma1 activation and actin filament redistribution. Mol. Biol. Cell 15 (2004) 1273-1286
    • (2004) Mol. Biol. Cell , vol.15 , pp. 1273-1286
    • Papakonstanti, E.A.1    Stournaras, C.2
  • 29
    • 35748959354 scopus 로고    scopus 로고
    • Actin cytoskeleton architecture and signaling in osmosensing
    • Papakonstanti E.A., and Stournaras C. Actin cytoskeleton architecture and signaling in osmosensing. Methods Enzymol. 428 (2007) 227-240
    • (2007) Methods Enzymol. , vol.428 , pp. 227-240
    • Papakonstanti, E.A.1    Stournaras, C.2
  • 30
    • 0035163237 scopus 로고    scopus 로고
    • Cooperative control of Akt phosphorylation, bcl-2 expression, and apoptosis by cytoskeletal microfilaments and microtubules in capillary endothelial cells
    • Flusberg D.A., Numaguchi Y., and Ingber D.E. Cooperative control of Akt phosphorylation, bcl-2 expression, and apoptosis by cytoskeletal microfilaments and microtubules in capillary endothelial cells. Mol. Biol. Cell 12 (2001) 3087-3094
    • (2001) Mol. Biol. Cell , vol.12 , pp. 3087-3094
    • Flusberg, D.A.1    Numaguchi, Y.2    Ingber, D.E.3
  • 31
    • 21044450363 scopus 로고    scopus 로고
    • Identification of an upstream regulatory pathway controlling actin-mediated apoptosis in yeast
    • Gourlay C.W., and Ayscough K.R. Identification of an upstream regulatory pathway controlling actin-mediated apoptosis in yeast. J. Cell. Sci. 118 (2005) 2119-2132
    • (2005) J. Cell. Sci. , vol.118 , pp. 2119-2132
    • Gourlay, C.W.1    Ayscough, K.R.2
  • 32
    • 0034597013 scopus 로고    scopus 로고
    • CD95 (APO-1/Fas) linkage to the actin cytoskeleton through ezrin in human T lymphocytes: a novel regulatory mechanism of the CD95 apoptotic pathway
    • Parlato S., Giammarioli A.M., Logozzi M., Lozupone F., Matarrese P., Luciani F., Falchi M., Malorni W., and Fais S. CD95 (APO-1/Fas) linkage to the actin cytoskeleton through ezrin in human T lymphocytes: a novel regulatory mechanism of the CD95 apoptotic pathway. EMBO J. 19 (2000) 5123-5134
    • (2000) EMBO J. , vol.19 , pp. 5123-5134
    • Parlato, S.1    Giammarioli, A.M.2    Logozzi, M.3    Lozupone, F.4    Matarrese, P.5    Luciani, F.6    Falchi, M.7    Malorni, W.8    Fais, S.9
  • 33
    • 0034925041 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase signaling controls levels of hypoxia-inducible factor 1
    • Jiang B.H., Jiang G., Zheng J.Z., Lu Z., Hunter T., and Vogt P.K. Phosphatidylinositol 3-kinase signaling controls levels of hypoxia-inducible factor 1. Cell Growth Differ. 12 (2001) 363-369
    • (2001) Cell Growth Differ. , vol.12 , pp. 363-369
    • Jiang, B.H.1    Jiang, G.2    Zheng, J.Z.3    Lu, Z.4    Hunter, T.5    Vogt, P.K.6
  • 34
    • 0037069690 scopus 로고    scopus 로고
    • Rho GTPases in cell biology
    • Etienne-Manneville S., and Hall A. Rho GTPases in cell biology. Nature 420 (2002) 629-635
    • (2002) Nature , vol.420 , pp. 629-635
    • Etienne-Manneville, S.1    Hall, A.2
  • 35
    • 0035836791 scopus 로고    scopus 로고
    • Rho signals to cell growth and apoptosis
    • Aznar S., and Lacal J.C. Rho signals to cell growth and apoptosis. Cancer Lett. 165 (2001) 1-10
    • (2001) Cancer Lett. , vol.165 , pp. 1-10
    • Aznar, S.1    Lacal, J.C.2
  • 36
    • 0032497699 scopus 로고    scopus 로고
    • Rho-regulated signals induce apoptosis in vitro and in vivo by a p53-independent, but Bcl2 dependent pathway
    • Esteve P., Embade N., Perona R., Jimenez B., del Peso L., Leon J., Arends M., Miki T., and Lacal J.C. Rho-regulated signals induce apoptosis in vitro and in vivo by a p53-independent, but Bcl2 dependent pathway. Oncogene 17 (1998) 1855-1869
    • (1998) Oncogene , vol.17 , pp. 1855-1869
    • Esteve, P.1    Embade, N.2    Perona, R.3    Jimenez, B.4    del Peso, L.5    Leon, J.6    Arends, M.7    Miki, T.8    Lacal, J.C.9
  • 37
    • 0033531955 scopus 로고    scopus 로고
    • Characterization of rac and cdc42 activation in chemoattractant-stimulated human neutrophils using a novel assay for active GTPases
    • Benard V., Bohl B.P., and Bokoch G.M. Characterization of rac and cdc42 activation in chemoattractant-stimulated human neutrophils using a novel assay for active GTPases. J. Biol. Chem. 274 (1999) 13198-13204
    • (1999) J. Biol. Chem. , vol.274 , pp. 13198-13204
    • Benard, V.1    Bohl, B.P.2    Bokoch, G.M.3
  • 38
    • 0033777071 scopus 로고    scopus 로고
    • Determination of GTP loading on Rho
    • Ren X.D., and Schwartz M.A. Determination of GTP loading on Rho. Methods Enzymol. 325 (2000) 264-272
    • (2000) Methods Enzymol. , vol.325 , pp. 264-272
    • Ren, X.D.1    Schwartz, M.A.2
  • 40
    • 0033611107 scopus 로고    scopus 로고
    • Cofilin phosphorylation and actin cytoskeletal dynamics regulated by rho- and Cdc42-activated LIM-kinase 2
    • Sumi T., Matsumoto K., Takai Y., and Nakamura T. Cofilin phosphorylation and actin cytoskeletal dynamics regulated by rho- and Cdc42-activated LIM-kinase 2. J. Cell Biol. 147 (1999) 1519-1532
    • (1999) J. Cell Biol. , vol.147 , pp. 1519-1532
    • Sumi, T.1    Matsumoto, K.2    Takai, Y.3    Nakamura, T.4
  • 41
    • 15744405757 scopus 로고    scopus 로고
    • Cytoskeleton-mediated death receptor and ligand concentration in lipid rafts forms apoptosis-promoting clusters in cancer chemotherapy
    • Gajate C., and Mollinedo F. Cytoskeleton-mediated death receptor and ligand concentration in lipid rafts forms apoptosis-promoting clusters in cancer chemotherapy. J. Biol. Chem. 280 (2005) 11641-11647
    • (2005) J. Biol. Chem. , vol.280 , pp. 11641-11647
    • Gajate, C.1    Mollinedo, F.2
  • 42
    • 21044458755 scopus 로고    scopus 로고
    • CD95 capping is ROCK-dependent and dispensable for apoptosis
    • Soderstrom T.S., Nyberg S.D., and Eriksson J.E. CD95 capping is ROCK-dependent and dispensable for apoptosis. J. Cell Sci. 118 (2005) 2211-2223
    • (2005) J. Cell Sci. , vol.118 , pp. 2211-2223
    • Soderstrom, T.S.1    Nyberg, S.D.2    Eriksson, J.E.3
  • 43
    • 21744445111 scopus 로고    scopus 로고
    • The actin cytoskeleton: a key regulator of apoptosis and ageing?
    • Gourlay C.W., and Ayscough K.R. The actin cytoskeleton: a key regulator of apoptosis and ageing?. Nat. Rev., Mol. Cell. Biol. 6 (2005) 583-589
    • (2005) Nat. Rev., Mol. Cell. Biol. , vol.6 , pp. 583-589
    • Gourlay, C.W.1    Ayscough, K.R.2
  • 44
    • 0035826165 scopus 로고    scopus 로고
    • Alterations in the focal adhesion kinase/Src signal transduction pathway correlate with increased migratory capacity of prostate carcinoma cells
    • Slack J.K., Adams R.B., Rovin J.D., Bissonette E.A., Stoker C.E., and Parsons J.T. Alterations in the focal adhesion kinase/Src signal transduction pathway correlate with increased migratory capacity of prostate carcinoma cells. Oncogene 20 (2001) 1152-1163
    • (2001) Oncogene , vol.20 , pp. 1152-1163
    • Slack, J.K.1    Adams, R.B.2    Rovin, J.D.3    Bissonette, E.A.4    Stoker, C.E.5    Parsons, J.T.6
  • 46
    • 0029795243 scopus 로고    scopus 로고
    • Focal adhesion kinase (pp125FAK) expression, activation and association with paxillin and p50CSK in human metastatic prostate carcinoma
    • Tremblay L., Hauck W., Aprikian A.G., Begin L.R., Chapdelaine A., and Chevalier S. Focal adhesion kinase (pp125FAK) expression, activation and association with paxillin and p50CSK in human metastatic prostate carcinoma. Int. J. Cancer 68 (1996) 164-171
    • (1996) Int. J. Cancer , vol.68 , pp. 164-171
    • Tremblay, L.1    Hauck, W.2    Aprikian, A.G.3    Begin, L.R.4    Chapdelaine, A.5    Chevalier, S.6
  • 47
    • 34249059285 scopus 로고    scopus 로고
    • Phosphorylation of FAK, PI-3K, and impaired actin organization in CK-positive micrometastatic breast cancer cells
    • Kallergi G., Mavroudis D., Georgoulias V., and Stournaras C. Phosphorylation of FAK, PI-3K, and impaired actin organization in CK-positive micrometastatic breast cancer cells. Mol. Med. 13 (2007) 79-88
    • (2007) Mol. Med. , vol.13 , pp. 79-88
    • Kallergi, G.1    Mavroudis, D.2    Georgoulias, V.3    Stournaras, C.4
  • 48
    • 0034715885 scopus 로고    scopus 로고
    • Regulation and functions of Rho-associated kinase
    • Amano M., Fukata Y., and Kaibuchi K. Regulation and functions of Rho-associated kinase. Exp. Cell Res. 261 (2000) 44-51
    • (2000) Exp. Cell Res. , vol.261 , pp. 44-51
    • Amano, M.1    Fukata, Y.2    Kaibuchi, K.3
  • 49
    • 14844293207 scopus 로고    scopus 로고
    • PAK and other Rho-associated kinases-effectors with surprisingly diverse mechanisms of regulation
    • Zhao Z.S., and Manser E. PAK and other Rho-associated kinases-effectors with surprisingly diverse mechanisms of regulation. Biochem. J. 386 (2005) 201-214
    • (2005) Biochem. J. , vol.386 , pp. 201-214
    • Zhao, Z.S.1    Manser, E.2
  • 50
    • 0842281652 scopus 로고    scopus 로고
    • Rho and Rac take center stage
    • Burridge K., and Wennerberg K. Rho and Rac take center stage. Cell 116 (2004) 167-179
    • (2004) Cell , vol.116 , pp. 167-179
    • Burridge, K.1    Wennerberg, K.2


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