Activation of membrane androgen receptors in colon cancer inhibits the prosurvival signals Akt/Bad in vitro and in vivo and blocks migration via vinculin/actin signaling

Molecular Medicine

Volumn 17, Issue 1-2, 2011, Pages 48-58

  Gu, Shuchen ^a   Papadopoulou, Natalia ^b   Nasir, Omaima ^a   Föller, Michael ^a   Alevizopoulos, Konstantinos ^c   Lang, Florian ^a   Stournaras, Christos ^a,b  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITY OF CRETE   (Greece)

^c Medexis Biotech SA   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; ACTIN; ANDROGEN RECEPTOR; APC PROTEIN; CYTOCHALASIN B; GENISTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAD; PROTEIN KINASE B; SMALL INTERFERING RNA; TESTOSTERONE; VINCULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL; CANCER INCIDENCE; CANCER INHIBITION; CELL ADHESION; CELL MIGRATION; CELL MOTILITY; CELL STRAIN CACO 2; CELL SURVIVAL; COLON CANCER; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RECEPTOR DOWN REGULATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TISSUE LEVEL;

ACTINS; ANIMALS; BCL-ASSOCIATED DEATH PROTEIN; CELL LINE, TUMOR; CELL MOVEMENT; COLONIC NEOPLASMS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MICE; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, ANDROGEN; SIGNAL TRANSDUCTION; VINCULIN;

EID: 78651490702     PISSN: 10761551     EISSN: None     Source Type: Journal    
DOI: 10.2119/molmed.2010.00120     Document Type: Article

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