Constitutive autotaxin transcription by Nmyc-amplified and non-amplified neuroblastoma cells is regulated by a novel AP-1 and SP-mediated mechanism and abrogated by curcumin

FEBS Letters

Volumn 586, Issue 20, 2012, Pages 3681-3691

  Farina, Antonietta R ^a   Cappabianca, Lucia ^a   Ruggeri, Pierdomenico ^a   Di Ianni, Natalia ^a   Ragone, Marzia ^a   Merolle, Stefania ^a   Sano, Kimihiko ^b   Stracke, Mary L ^c   Horowitz, Jonathan M ^d   Gulino, Alberto ^e   MacKay, Andrew R ^a  

^a UNIVERSITY OF L'AQUILA   (Italy)

^b KOBE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c NATIONAL CANCER INSTITUTE   (United States)

^d NORTH CAROLINA STATE UNIVERSITY   (United States)

^e SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

AP 1; Autotaxin; Curcumin; Internally initiated SP3; Neuroblastoma; SP; Transcription

Indexed keywords

AUTOTAXIN; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR SP; TRANSCRIPTION FACTOR SP3;

ARTICLE; AUTOTAXIN GENE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; NEUROBLASTOMA CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATOR GENE; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION REGULATION;

CELL LINE, TUMOR; CURCUMIN; CYCLIC AMP; GENE DELETION; GENES, REPORTER; HUMANS; NEUROBLASTOMA; PHOSPHORIC DIESTER HYDROLASES; PROTO-ONCOGENE PROTEINS C-MYC; RESPONSE ELEMENTS; SP TRANSCRIPTION FACTORS; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION;

EID: 84867582264     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2012.08.026     Document Type: Article

References (42)

1. M.L. Stracke, H.C. Krutzsch, E.J. Unsworth, A. Arestad, V. Cioce, E. Schiffman, and L.A. Liotta Identification, purification, and partial sequence analysis of Autotaxin, a novel motility-stimulating protein J. Biol. Chem. 267 1992 2524 2529
2. M.L. Stracke, T. Clair, and L.A. Liotta Autotaxin, tumor motility-stimulating exophosphodiesterase Adv. Enzyme Regul. 3 1997 135 144
3. T. Clair, H.Y. Lee, L.A. Liotta, and M.L. Stracke Autotaxin is an exoenzyme possessing 5′-nucleotide phosphodiesterase/ATP pyrophosphatase and ATPase activities J. Biol. Chem. 272 1997 996 1001
4. M. Umezu-Goto, Y. Kishi, A. Taira, K. Hama, N. Dohmae, K. Takio, T. Yamori, G.B. Mills, K. Inoue, J. Aoki, and H. Arai Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production J. Cell Biol. 158 2002 227 233
5. S. Liu, M. Murph, N. Panupinthu, and G.B. Mills ATX-LPA receptor axis in inflammation and cancer Cell Cycle 8 2009 3695 3701
6. A.J. Houben, and W.H. Moolenaar Autotaxin and LPA receptor signalling in cancer Cancer Metastasis Rev. 30 2011 557 565
7. F.N. van Leeuwen, B.N. Giepmans, L.A. van Meeteren, and W.H. Moolenaar Lysophosphatidic acid: mitogen and motility factor Biochem. Soc. Trans. 31 2003 1209 1212
8. S.W. Nam, T. Clair, C.K. Campo, H.Y. Lee, L.A. Liotta, and M.L. Stracke Autotaxin (ATX), a potent tumor motogen, augments invasive and metastatic potential of ras-transformed cells Oncogene 19 2000 241 247
9. S.W. Nam, T. Clair, Y.S. Kim, A. McMarlin, E. Schiffmann, L.A. Liotta, and M.L. Stracke Autotaxin (NPP-2), a metastasis-enhancing motogen, is an angiogenic factor Cancer Res. 61 2001 6938 6944
10. M.M. Ptaszynska, M.L. Pendrak, M.L. Stracke, and D.D. Roberts Autotaxin signaling via lysophosphatidic acid receptors contributes to vascular endothelial growth factor-induced endothelial cell migration Mol. Cancer Res. 8 2010 309 321
11. M. David, E. Wannecq, F. Descotes, S. Jansen, B. Deux, J. Ribeiro, C.M. Serre, S. Grès, N. Bendriss-Vermare, M. Bollen, S. Saez, J. Aoki, J.S. Saulnier-Blanche, P. Clézardin, and O. Peryuchaud Cancer cell expression of autotaxin controls bone metastasis formation in mouse through lysophosphatidic acid-dependent activation of osteoclasts PLoS One 5 2010 e9741
12. S. Liu, M. Umezu-Goto, M. Murph, Y. Lu, W. Liu, F. Zhang, S. Yu, L.C. Stephens, X. Cui, G. Murrow, K. Coombes, W. Muller, M.C. Hung, C.M. Perou, A.V. Lee, X. Fang, and G.B. Mills Expression of autotaxin and lysophosphatidic acid receptors increases mammary tumorigenesis, invasion and metastases Cancer Cell 15 2009 539 550
13. G. Zhang, Z. Zhao, S. Xu, L. Ni, and X. Wang Expression of autotaxin mRNA in human hepatocellular carcinoma Chin. Med. J. (Engl.) 112 1999 330 332
14. Y. Yang, Lj. Mou, N. Liu, and M.S. Tsao Autotaxin expression in non-small-cell lung cancer Am. J. Respir. Cell Mol. Biol. 21 1999 216 222
15. K.R. Baumforth, J.R. Flavell, G.M. Reynolds, G. Davies, T.R. Pettit, W. Wei, S. Morgan, T. Stankovic, Y. Kishi, H. Arai, M. Nowakova, G. Pratt, J. Aoki, M.J. Wakelam, L.S. Young, and P.G. Murrey Induction of autotaxin by the Epstein-Barr virus promotes the growth and survival of Hodgkin lymphoma cells Blood 106 2005 2138 2146
16. Y. Kishi, S. Okudaira, M. Tanaka, K. Hama, D. Shida, J. Kitayama, T. Yamori, J. Aoki, T. Fujimaki, and H. Arai Autotaxin is overexpressed in glioblastoma multiforme and contributes to cell motility of glioblastoma by converting lysophosphatidylcholine to lysophosphatidic acid J. Biol. Chem. 281 2006 17492 17500
17. A. Kehlen, N. Englert, A. Seifert, T. Klonisch, H. Dralle, J. Langner, and C. Hoang-Vu Expression, regulation and function of autotaxin in thyroid carcinomas Int. J. Cancer 109 2004 833 838
18. S. Vidot, J. Witham, R. Agarwal, S. Greenhough, H.S. Bamrah, G.J. Tigyi, S.B. Kaye, and A. Richardson Autotaxin delays apoptosis induced by carboplatin in ovarian cancer cells Cell Signal. 22 2010 926 935
19. M.J. Stassar, G. Devitt, M. Brosius, L. Rinnab, J. Prang, T. Schradin, J. Simon, S. Petersen, A. Kopp-Schneider, and M. Zöller Identification of human renal cell carcinoma associated genes by suppression subtractive hybridization Br. J. Cancer 85 2001 1372 1382
20. H. Kawagoe, M.L. Stracke, H. Nakamura, and K. Sano Expression and transcriptional regulation of the PD-I alpha/autotaxin gene in neuroblastoma Cancer Res. 57 1997 2516 2521
21. S. Pahlman, and F. Hedborg Development of the Neural Crest and Sympathetic Nervous System G.M. Brodeur, T. Sawada, Y. Tsuchida, P.A. Voute, Neuroblastoma 2000 Elsevier Science BV 9 19
22. G.M. Brodeur, and J.M. Maris Neuroblastoma P.A. Pizzo, D.G. Poplack, Principles and Practice of Pediatric Oncology 2006 Lippincott, Williams and Wilkinson 933 970
23. H. Kawagoe, O. Soma, J. Goji, N. Nishimura, M. Narita, J. Inazawa, H. Nakamura, and K. Sano Molecular cloning and chromosomal assignment of the human brain-type phosphodiesterase I/nucleotide pyrophosphatase gene (PDNP2) Genomics 30 1995 380 384
24. J. Dufner-Beattie, R.S. Lemons, and A. Thorburn Retinoic acid-induced expression of Autotaxin in N-myc-amplified neuroblastoma cells Mol. Carcinog. 30 2001 181 189
25. M. Chen, and K.L. O'Connor Integrin alpha6beta4 promotes expression of autotaxin/ENPP2 autocrine motility factor in breast carcinoma cells Oncogene 24 2005 5125 5130
26. S. Li, B. Wang, J. Xu, and J. Zhang Autotaxin is induced by TSA through HDAC3 and HDAC7 inhibits and antagonizes the TSA-induced cell apoptosis Mol. Cancer. 2011 10 18
27. E.J. Black, T. Clair, J. Delrow, P. Neiman, and D.A. Gillespie Microarray analysis identifies Autotaxin, a tumour cell motility and angiogenic factor with lysophospholipase D activity, as a specific target of cell transformation by v-Jun Oncogene 23 2004 2357 2366
28. T.M. Williams, M.E. Williams, R. Kuick, D. Misek, K. McDonagh, S. Hanash, and J.W. Innis Candidate downstream regulated genes of HOX group 13 transcription factors with and without monomeric DNA binding capability Dev. Biol. 279 2005 462 480
29. J.D. Dignam, P. Martin, B.S. Shastry, and R.G. Roeder Eukaryotic gene transcription with purified components Methods Enzymol. 101 1983 582 598
30. A.R. Farina, A. Tacconelli, A. Vacca, M. Maroder, A. Gulino, and A.R. Mackay Transcriptional up-regulation of matrix metalloproteinase-9 expression during spontaneous epithelial to neuroblast phenotype conversion by SK-N-SH neuroblastoma cells, involved in enhanced invasivity, depends upon GT-box and nuclear factor kappa B elements Cell Growth Differ. 10 1999 353 367
31. L. Cappabianca, A.R. Farina, A. Tacconelli, A. Gulino, R. Mantovani, and A.R. Mackay Reconstitution of TIMP-2 expression in SH-SY5Y neuroblastoma cells by 5-azacytidine is mediated transcriptionally by NF-Y through an inverted CCAAT site Exp. Cell Res. 286 2003 209 218
32. M. Flavin, L. Cappabianca, C. Kress, H. Thomassin, and T. Grange Nature of the accessible chromatin at a glucocorticoid-responsive enhancer Mol. Cell Biol. 24 2004 7891 7901
33. W.G. Burnette "Western blotting": electrophoretic transfer of proteins from sodium dodecyl sulphate polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein Anal. Biochem. 112 1981 195 203
34. S.B. Kennett, A.J. Udvadia, and J.M. Horowitz Sp3 encodes multiple proteins that differ in their capacity to stimulate or repress transcription Nucleic Acids Res. 25 1997 3110 3117
35. K.M. Walton, R.P. Rehfuss, J.C. Chrivia, J.E. Lochner, and R.H. Goodman A dominant repressor of cyclic adenosine 3′, 5′-monophosphate (cAMP)-regulated enhancer-binding protein activity inhibits the cAMP-mediated induction of the somatostatin promoter in vivo Mol. Endocrinol. 6 1992 647 655
36. C.J. Dragland-Meserve, J.D. Rothermel, M.J. Houlihan, and L.H. Botelho Inhibition of cyclic AMP-dependent protein kinase-induced changes in the kinetic properties of hepatic pyruvate kinase by the specific cyclic AMP antagonist, the (Rp)-diastereomer of adenosine cyclic 3′,5′-phosphorothioate J. Cyclic Nucleotide Protein Phosphor. Res. 10 1985 371 382
37. D.J. Singh, and K. Misra Curcuminoids as inhibitors of thioredoxin reductase: a receptor based pharmacophore study with distance mapping of the active site Bioinformation 4 2009 187 192
38. K.M. Dhandapani, V.B. Mahesh, and D.W. Brann Curcumin suppresses growth and chemo resistance of human glioblastoma cells via AP-1 and NFkB transcription factors J. Neurochem. 102 2007 522 538
39. S. Han, Y.S. Keum, H.J. Seo, and Y.J. Suhr Curcumin suppresses activation of NFkB and AP-1 induced by phorbol ester in cultured human promyelocytic leukemia cells J. Biochem. Mol. Biol. 35 2002 337 342
40. Q. Kang, and A. Chen Curcumin inhibits srebp-2 expression in activated hepatic stellate cells in vitro by reducing the activity of specificity protein-1 Endocrinology 150 2009 5384 5394
41. R. Eferl, and E.F. Wagner AP-1: a double-edged sword in tumorigenesis Nat. Rev. Cancer 3 2003 859 868
42. M. Bakovic, K.A. Waite, and D.E. Vance Functional significance of Sp1, Sp2, and Sp3 transcription factors in regulation of the murine CTP: phosphocholine cytidylyltransferase alpha promoter J. Lipid Res. 41 2000 583 594