Retinoic acid-induced expression of autotaxin in N-myc-amplified neuroblastoma cells

Molecular Carcinogenesis

Volumn 30, Issue 4, 2001, Pages 181-189

  Dufner Beattie, J ^a   Lemons, R S ^a   Thorburn, A ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

Autotaxin; N myc; Neuroblastoma; Retinoic acid

Indexed keywords

AUTOCRINE MOTILITY FACTOR; AUTOTAXIN; RETINOIC ACID; UNCLASSIFIED DRUG;

ADRENERGIC SYSTEM; ARTICLE; CELL DIFFERENTIATION; CYTOGENETICS; GENE AMPLIFICATION; GENE EXPRESSION REGULATION; GENE LOCUS; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; NEUROBLASTOMA; NEUROBLASTOMA CELL; ONCOGENE C MYB; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN SYNTHESIS;

ANTINEOPLASTIC AGENTS; AUTOCRINE MOTILITY FACTOR; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; BLOTTING, NORTHERN; BLOTTING, WESTERN; CELL LINE, TRANSFORMED; CELL TRANSFORMATION, NEOPLASTIC; DNA-BINDING PROTEINS; GENE AMPLIFICATION; GENE EXPRESSION; GENES, MYC; GLYCOPROTEINS; HUMANS; MULTIENZYME COMPLEXES; NEUROBLASTOMA; PHOSPHODIESTERASE I; PYROPHOSPHATASES; REPRESSOR PROTEINS; RETROVIRIDAE; RNA, MESSENGER; TRETINOIN;

EID: 0035042178     PISSN: 08991987     EISSN: None     Source Type: Journal    
DOI: 10.1002/mc.1028     Document Type: Article

References (62)

1. Neuroblastoma
2. Neuroblastoma: Effect of genetic factors on prognosis and treatment
3. Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas
4. Expression of N-myc by neuroblastomas with one or multiple copies of the oncogene
5. Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage
6. Clinical implications of oncogene activation in human neuroblastomas
7. In vitro differentiation of human neuroblastoma cells by vasoactive intestinal peptide
8. Phenotypic changes of human neuroblastoma cells in culture induced by 12-O-tetradecanoyl-phorbol-13-acetate
9. Kinetics and concentration effects of TPA-induced differentiation of cultured human neuroblastoma cells
10. Retinoic acid-induced differentiation of cultured human neuroblastoma cells: A comparison with phor bol ester-induced differentiation
11. Differentiation of human neuroblastoma recapitulates neural crest development
12. Retinoic acid-induced growth inhibition and morphologic differentiation of human neuroblastoma cells in vitro
13. Effects of retinoic acid (RA) on the growth and phenotypic expression of several human neuroblastoma cell lines
14. The retinoid receptors
15. Retinoic receptors in transcriptional regulation
16. The RXR heterodimers and orphan receptors
17. A decade of molecular biology of retinoic acid receptors
18. Identification, purification, and partial sequence analysis of autotaxin, a novel motility-stimulating protein
19. Molecular cloning and chromosomal assignment of the human brain-type phosphodiesterasel/nucleotide pyrophosphatase gene (PDNP2)
20. Stimulation of tumor cell motility linked to phosphodiesterase catalytic site of autotaxin
21. cDNA cloning of the human tumor motility-stimulating protein, autotaxin, reveals a homology with phosphodiesterases
22. Autotaxin, tumor motility-stimulating exophosphodiesterase
23. Expression and transcriptional regulation of the PD-lα/autotaxin gene in neuroblastoma
24. Autotaxin (ATX), a potent tumor motogen, augments invasive and metastatic potential of ras-transformed cells
25. Conversion of mRNA into double-stranded cDNA
26. Identifying differences in mRNA expression by representational difference analysis of cDNA
27. Advanced mammalian gene transfer: High titre retroviral vectors with drug selection markers and a complementary helper-free packaging cell line
28. Mad-Max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3
29. Rapid detection of octamer binding proteins with 'mini-extracts,' prepared from a small number of cells
30. Serum and glucocorticoid regulation of gene transcription and expression of the prostaglandin H synthase-1 and prostaglandin H synthase-2 isozymes
31. Genomic sequencing
32. Cloning, chromosomal localization, and tissue expression of autotaxin from human teratocarcinoma cells
33. Retinoic acid treatment of human neuroblastoma cells is associated with decreased N-myc expression
34. Decreased expression of N-myc precedes retinoic acid-induced morphological differentiation of human neuroblastoma
35. Autoregulation of the human N-myc oncogene is disrupted in amplified but not single-copy neuroblastoma cell lines
36. Prolonged N-myc protein half-life in a neuroblastoma cell line lacking N-myc amplification
37. Myc-Max-Mad: A transcription factor network controlling cell cycle progression, differentiation and death
38. Control of cell proliferation by myc
39. Flipping the myc switch
40. Mad: A heterodimeric partner for Max that antagonizes myc transcriptional activity
41. Mad3 and Mad4: Novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation
42. Suppression of myc, but not E1a, transformation activity by max-associated proteins, mad and mxi1
43. Effects of the myc oncogene antagonist, mad, on proliferation, cell cycling and the malignant phenotype of human brain tumour cells
44. Differential effects by mad and max on transformation by cellular and viral oncoproteins
45. Expression of the mad gene during cell differentiation in vivo and its inhibition of cell growth in vitro
46. Inhibition of cell proliferation by the mad1 transcriptional repressor
47. Repression of myc-ras cotransformation by mad is mediated by multiple protein-protein interactions
48. Co-amplification and concomitant high levels of expression of a DEAD box gene with MYCN in human neuroblastoma
49. The DDX1 gene maps within 400 kbp 5′ to MYCN and is frequently coamplified in human neuroblastoma
50. Co-amplification of MYCN and a DEAD box gene (DDX1) in primary neuroblastoma
51. Amplification of a DEAD box gene (DDX1) with the MYCN gene in neuroblastomas as a result of cosegregation of sequences flanking the MYCN locus
52. Investigation of co-amplification of the candidate genes ornithine decarboxylase, ribonucleotide reductase, syndecan-1 and a DEAD box gene, DDX1, with N-myc in neuroblastoma
53. High-resolution mapping of the N-myc amplicon core domain in neuroblastomas
54. Evidence for two tumour suppressor loci on chomosomal bands 1p35-36 involved in neuroblastoma: One probably imprinted, another associated with N-myc amplification
55. Two distinct deleted regions on the short arm of chromosome 1 in neuroblastoma
56. Loss of heterozygosity for the short arm of chromosome 1 in human neuroblastomas: Correlation with N-myc amplification
57. Loss of heterozygosity for chromosome 1 or 14 defines subsets of advanced neuroblastomas
58. There may be two suppressor genes on chromosome arm 1p closely associated with biologically distinct subtypes of neuroblastoma
59. A region of consistent deletion in neuroblastoma maps within human chromosome 1p36.2-1p36.3
60. 13-cis-retinoic acid(NSC 122758) in the treatment of children with metastatic neuroblastoma unresponsive to conventional chemotherapy: Report from the Childrens Cancer Study Group
61. Retinoic acid-enhanced invasion through reconstituted basement membrane by human SK-N-SH neuroblastoma cells involves membrane-associated tissue-type plasminogen activator
62. The role of cellular motility in the invasion of human neuroblastoma cells with or without N-myc amplification and expression