Adenoviral dominant-negative soluble PDGFRβ improves hepatic collagen, systemic hemodynamics, and portal pressure in fibrotic rats

Journal of Hepatology

Volumn 57, Issue 5, 2012, Pages 967-973

  Reichenbach, V ^a   Fernandez Varo G ^a   Casals, G ^a   Oro D ^a   Ros, J ^a   Melgar Lesmes, P ^a   Weiskirchen, R ^b   Morales Ruiz, M ^a   Jimenez W ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

Author keywords

Ad sPDGFR adenoviruses; Hepatic collagen; PDGFR ; Portal pressure; Signaling pathway blockade; Systemic hemodynamics

Indexed keywords

ADENOVIRUS VECTOR; BETA GALACTOSIDASE; CARBON TETRACHLORIDE; COLLAGEN; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR;

ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CHEMOTAXIS; CONTROLLED STUDY; HEMODYNAMICS; HUMAN; HUMAN CELL; KIDNEY FUNCTION; LIVER CIRRHOSIS; LIVER FIBROSIS; LIVER FUNCTION; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PORTAL VEIN BLOOD PRESSURE; PRIORITY JOURNAL; RAT;

ACTINS; ADENOVIRIDAE; ANIMALS; BETA-GALACTOSIDASE; CARBON TETRACHLORIDE; COLLAGEN; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; HEMODYNAMICS; LIVER; LIVER CIRRHOSIS; MALE; PORTAL PRESSURE; RATS; RATS, WISTAR; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; SIGNAL TRANSDUCTION; TRANSDUCTION, GENETIC;

EID: 84867574469     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2012.07.012     Document Type: Article

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