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Volumn 53, Issue 6, 2010, Pages 1041-1048

Inactivation of extrahepatic vascular Akt improves systemic hemodynamics and sodium excretion in cirrhotic rats

Author keywords

AA Akt adenoviruses; Arterial vasodilation; Ascites; Cirrhosis; Endothelial nitric oxide synthase (eNOS); Nitric oxide (NO); Renal function; Serine threonine kinase Akt; Systemic hemodynamics

Indexed keywords

BETA GALACTOSIDASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; INDUCIBLE NITRIC OXIDE SYNTHASE; MUTANT PROTEIN; NITRIC OXIDE; PROTEIN KINASE B; SODIUM;

EID: 78049458666     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2010.05.031     Document Type: Article
Times cited : (6)

References (21)
  • 1
    • 0034087697 scopus 로고    scopus 로고
    • Renal and circulatory dysfunction in cirrhosis. Lights and shadows in an important clinical problem
    • V. Arroyo, and W. Jiménez Renal and circulatory dysfunction in cirrhosis. Lights and shadows in an important clinical problem J Hepatol 32 2000 157 170
    • (2000) J Hepatol , vol.32 , pp. 157-170
    • Arroyo, V.1    Jiménez, W.2
  • 2
    • 0028093496 scopus 로고
    • Impaired responsiveness to endogenous vasoconstrictors and endothelium derived vasoactive factors in cirrhosis
    • W. Jimenez, and J. Rodés Impaired responsiveness to endogenous vasoconstrictors and endothelium derived vasoactive factors in cirrhosis Gastroenterology 107 1994 1201 1203
    • (1994) Gastroenterology , vol.107 , pp. 1201-1203
    • Jimenez, W.1    Rodés, J.2
  • 4
    • 0021964592 scopus 로고
    • Temporal relationship between hyperaldosteronism, sodium retention and ascites formation in rats with experimental cirrhosis
    • W. Jiménez, A. Martinez-Pardo, V. Arroyo, J. Bruix, A. Rimola, and J. Gaya Temporal relationship between hyperaldosteronism, sodium retention and ascites formation in rats with experimental cirrhosis Hepatology 5 1985 245 250
    • (1985) Hepatology , vol.5 , pp. 245-250
    • Jiménez, W.1    Martinez-Pardo, A.2    Arroyo, V.3    Bruix, J.4    Rimola, A.5    Gaya, J.6
  • 6
    • 0033542414 scopus 로고    scopus 로고
    • Regulation of endothelium-derived nitric oxide production by the protein kinase Akt
    • D. Fulton, J.P. Gratton, T.J. McCabe, J. Fontana, Y. Fujio, and K. Walsh Regulation of endothelium-derived nitric oxide production by the protein kinase Akt Nature 399 1999 597 601
    • (1999) Nature , vol.399 , pp. 597-601
    • Fulton, D.1    Gratton, J.P.2    McCabe, T.J.3    Fontana, J.4    Fujio, Y.5    Walsh, K.6
  • 7
    • 0033522927 scopus 로고    scopus 로고
    • Akt mediates cytoprotection of endothelial cells by vascular endothelial growth factor in an anchorage-dependent manner
    • Y. Fujio, and K. Walsh Akt mediates cytoprotection of endothelial cells by vascular endothelial growth factor in an anchorage-dependent manner J Biol Chem 274 1999 16349 16354
    • (1999) J Biol Chem , vol.274 , pp. 16349-16354
    • Fujio, Y.1    Walsh, K.2
  • 8
    • 0032319508 scopus 로고    scopus 로고
    • Recombinant adenovirus-mediated expression in nervous system of genes coding for ion channels and other molecules involved in synaptic function
    • M.U. Ehrengruber, M. Lanzrein, Y. Xu, M.C. Jasek, D.B. Kantor, and E.M. Schuman Recombinant adenovirus-mediated expression in nervous system of genes coding for ion channels and other molecules involved in synaptic function Methods Enzymol 293 1998 483 503
    • (1998) Methods Enzymol , vol.293 , pp. 483-503
    • Ehrengruber, M.U.1    Lanzrein, M.2    Xu, Y.3    Jasek, M.C.4    Kantor, D.B.5    Schuman, E.M.6
  • 10
  • 14
    • 0026518464 scopus 로고
    • Pathogenesis of arterial hypotension in cirrhotic rats with ascites: Role of endogenous nitric oxide
    • J. Claria, W. Jimenez, J. Ros, M. Asbert, A. Castro, and V. Arroyo Pathogenesis of arterial hypotension in cirrhotic rats with ascites: role of endogenous nitric oxide Hepatology 15 1992 343 349
    • (1992) Hepatology , vol.15 , pp. 343-349
    • Claria, J.1    Jimenez, W.2    Ros, J.3    Asbert, M.4    Castro, A.5    Arroyo, V.6
  • 16
    • 0027946525 scopus 로고
    • Increased nitric oxide-dependent vasorelaxation in aortic rings of cirrhotic rats with ascites
    • J. Claria, W. Jimenez, J. Ros, M. Rigol, P. Angeli, and V. Arroyo Increased nitric oxide-dependent vasorelaxation in aortic rings of cirrhotic rats with ascites Hepatology 20 1994 1615 1621
    • (1994) Hepatology , vol.20 , pp. 1615-1621
    • Claria, J.1    Jimenez, W.2    Ros, J.3    Rigol, M.4    Angeli, P.5    Arroyo, V.6
  • 17
    • 0027178984 scopus 로고
    • Impaired responsiveness to angiotensin II in experimental cirrhosis: Role of nitric oxide
    • A. Castro, W. Jimenez, J. Claria, J. Ros, J.M. Martinez, and M. Bosch Impaired responsiveness to angiotensin II in experimental cirrhosis: role of nitric oxide Hepatology 18 1993 367 372
    • (1993) Hepatology , vol.18 , pp. 367-372
    • Castro, A.1    Jimenez, W.2    Claria, J.3    Ros, J.4    Martinez, J.M.5    Bosch, M.6
  • 18
    • 0034957736 scopus 로고    scopus 로고
    • Hemodynamic, renal and endocrine effects of acute inhibition of nitric oxide synthase in compensated cirrhosis
    • G. La Villa, G. Barletta, P. Pantaleo, R. Del Bene, F. Vizzutti, and S. Vecchiarino Hemodynamic, renal and endocrine effects of acute inhibition of nitric oxide synthase in compensated cirrhosis Hepatology 34 2001 19 27
    • (2001) Hepatology , vol.34 , pp. 19-27
    • La Villa, G.1    Barletta, G.2    Pantaleo, P.3    Del Bene, R.4    Vizzutti, F.5    Vecchiarino, S.6
  • 19
    • 20144389597 scopus 로고    scopus 로고
    • The role of nitric oxide in the pathogenesis of systemic and splanchnic vasodilation in cirrhotic rats before and after the onset of ascites
    • P. Angeli, G. Fernández-Varo, V. Dalla Libera, S. Fasolato, A. Galioto, and V. Arroyo The role of nitric oxide in the pathogenesis of systemic and splanchnic vasodilation in cirrhotic rats before and after the onset of ascites Liver Int 25 2005 429 437
    • (2005) Liver Int , vol.25 , pp. 429-437
    • Angeli, P.1    Fernández-Varo, G.2    Dalla Libera, V.3    Fasolato, S.4    Galioto, A.5    Arroyo, V.6
  • 20
    • 0032738990 scopus 로고    scopus 로고
    • Impaired endothelial nitric oxide synthase activity associated with enhanced caveolin binding in experimental cirrhosis in the rat
    • V. Shah, M. Toruner, F. Haddad, G. Cadelina, A. Papapetropoulos, and K. Choo Impaired endothelial nitric oxide synthase activity associated with enhanced caveolin binding in experimental cirrhosis in the rat Gastroenterology 117 1999 1222 1228
    • (1999) Gastroenterology , vol.117 , pp. 1222-1228
    • Shah, V.1    Toruner, M.2    Haddad, F.3    Cadelina, G.4    Papapetropoulos, A.5    Choo, K.6
  • 21
    • 0035902558 scopus 로고    scopus 로고
    • NCX-1000, a NO-releasing derivative of ursodeoxycholic acid, selectively delivers NO to the liver and protects against development of portal hypertension
    • S. Fiorucci, E. Antonelli, O. Morelli, A. Mencarelli, A. Casini, and T. Mello NCX-1000, a NO-releasing derivative of ursodeoxycholic acid, selectively delivers NO to the liver and protects against development of portal hypertension Proc Natl Acad Sci USA 98 2001 8897 8902
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 8897-8902
    • Fiorucci, S.1    Antonelli, E.2    Morelli, O.3    Mencarelli, A.4    Casini, A.5    Mello, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.