HTERT gene amplification and clinical significance in pleural effusions of patients with lung cancer

Clinical Lung Cancer

Volumn 13, Issue 6, 2012, Pages 494-499

  Cha, Na ^a   Li, Xiao Yan ^a   Zhao, Yu Jie ^a   Wang, En Hua ^a   Wu, Guang Ping ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Carcinoma cell; Cytopathology; Micrometastasis; Quantitative polymerase chain reaction; Reactive mesothelial cell

Indexed keywords

TELOMERASE REVERSE TRANSCRIPTASE;

ADULT; AGED; ANALYTIC METHOD; ARTICLE; CANCER PATIENT; CARCINOMA CELL; CONTROLLED STUDY; CYTODIAGNOSIS; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; EARLY DIAGNOSIS; FEMALE; GENE; GENE AMPLIFICATION; HTERT GENE; HUMAN; HUMAN CELL; LUNG ADENOCARCINOMA; LUNG CANCER; LUNG SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; MESOTHELIUM CELL; MICROMETASTASIS; PLEURA EFFUSION; PLEURA METASTASIS; POLYMERASE CHAIN REACTION; PREDICTIVE VALUE; QUANTITATIVE ANALYSIS; SENSITIVITY AND SPECIFICITY;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, SMALL CELL; FEMALE; GENE AMPLIFICATION; HUMANS; LUNG DISEASES; LUNG NEOPLASMS; MALE; MIDDLE AGED; NEOPLASM MICROMETASTASIS; NUCLEIC ACID AMPLIFICATION TECHNIQUES; PLEURAL EFFUSION; PLEURAL EFFUSION, MALIGNANT; PLEURAL NEOPLASMS; POLYMERASE CHAIN REACTION; PREDICTIVE VALUE OF TESTS; SENSITIVITY AND SPECIFICITY; TELOMERASE; TUMOR MARKERS, BIOLOGICAL;

EID: 84867513147     PISSN: 15257304     EISSN: 19380690     Source Type: Journal    
DOI: 10.1016/j.cllc.2012.01.007     Document Type: Article

References (38)

1. C. Autexier, N.F. Lue The structure and function of telomerase reverse transcriptase Annu Rev Biochem 75 2006 493 517
2. T.M. Nakamura, G.B. Morin, K.B. Chapman Telomerase catalytic subunit homologs from fission yeast and human Science 277 1997 955 959
3. M. Meyerson, C.M. Counter, E.N. Eaton hEST 2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization Cell 90 1997 785 795
4. L. Harrington, W. Zhou, T. McPhail Human telomerase contains evolutionarily conserved catalytic and structural subunits Genes Dev 11 1997 3109 3115
5. A. Kilian, D.D. Bowtell, H.E. Abud Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types Hum Mol Genet 6 1997 2011 2019
6. K. Harada, K. Kurisu, K. Arita Telomerase activity in central nervous system malignant lymphoma Cancer 86 1999 1050 1055
7. I. Bièche, C. Noguès, V. Paradis Quantitation of hTERT gene expression in sporadic breast tumors with a real-time reverse transcription-polymerase chain reaction assay Clin Cancer Res 6 2000 452 459
8. B.K. Lee, E. Diebel, F.W. Neukam Diagnostic and prognostic relevance of expression of human telomerase subunits in oral cancer Int J Oncol 19 2001 1063 1068
9. A. Marchetti, C. Pellegrini, F. Buttitta Prediction of survival in stage I lung carcinoma patients by telomerase function evaluation Lab Invest 82 2002 729 736
10. L. Wang, J.C. Soria, B.L. Kemp hTERT expression is a prognostic factor of survival in patients with stage I non-small cell lung cancer Clin Cancer Res 8 2002 2883 2889
11. Y. Fujita, T. Fujikane, S. Fujiuchi The diagnostic and prognostic relevance of human telomerase reverse transcriptase mRNA expression detected in situ in patients with nonsmall cell lung carcinoma Cancer 98 2003 1008 1013
12. M. Krams, B. Hero, F. Berthold Full-length telomerase reverse transcriptase messenger RNA is an independent prognostic factor in neuroblastoma Am J Pathol 162 2003 1019 1026
13. A. Ohali, S. Avigad, I.J. Cohen Association between telomerase activity and outcome in patients with nonmetastatic Ewing family of tumors J Clin Oncol 21 2003 3836 3843
14. A. Tchirkov, C. Rolhion, J.L. Kémény Clinical implications of quantitative real-time RT-PCR analysis of hTERT gene expression in human gliomas Br J Cancer 88 2003 516 520
15. S. Lantuejoul, J.C. Soria, D. Moro-Sibilot Differential expression of telomerase reverse transcriptase (hTERT) in lung tumours Br J Cancer 90 2004 1222 1229
16. X. Fan, Y. Wang, J. Kratz hTERT gene amplification and increased mRNA expression in central nervous system embryonal tumors Am J Pathol 162 2003 1763 1769
17. A. Zhang, C. Zheng, M. Hou Amplification of the telomerase reverse transcriptase (hTERT) gene in cervical carcinomas Genes Chromosomes Cancer 34 2002 269 275
18. C.Q. Zhu, J.C. Cutz, N. Liu Amplification of telomerase (hTERT) gene is a poor prognostic marker in non-small-cell lung cancer Br J Cancer 94 2006 1452 1459
19. A. Zhang, C. Zheng, C. Lindvall Frequent amplification of the telomerase reverse transcriptase gene in human tumors Cancer Res 60 2000 6230 6235
20. G. Saretzki, S. Petersen, I. Petersen hTERT gene dosage correlates with telomerase activity in human lung cancer cell lines Cancer Lett 176 2002 81 91
21. M. Marel, B. Stastny, L. Melínová Diagnosis of pleural effusions: experience with clinical studies, 1986-1990 Chest 107 1995 1598 1603
22. K.N. Fenton, J.D. Richardson Diagnosis and management of malignant pleural effusions Am J Surg 170 1995 69 74
23. S.M. Ghayumi, S. Mehrabi, M. Doroudchi Diagnostic value of tumor markers for differentiating malignant and benign pleural effusions of Iranian patients Pathol Oncol Res 11 2005 236 241
24. A.M. Afify, R. Stern, C.W. Michael Differentiation of mesothelioma from adenocarcinoma in serous effusions: the role of hyaluronic acid and CD44 localization Diagn Cytopathol 32 2005 145 150
25. A.M. Afify, B.M. Ai-Khafaji, A.F. Paulino Diagnostic use of muscle markers in the cytologic evaluation of serous fluids Appl Immunohistochem Mol Morphol 10 2002 178 182
26. E. Politi, C. Kandaraki, C. Apostolopoulou Immunocytochemical panel for distinguishing between carcinoma and reactive mesothelial cells in body cavity fluids Diagn Cytopathol 32 2005 151 155
27. N.C. Ordóñez The immunohistochemical diagnosis of mesothelioma: a comparative study of epithelioid mesothelioma and lung adenocarcinoma Am J Surg Pathol 27 2003 1031 1051
28. H. Yaziji, H. Battifora, T.S. Barry Evaluation of 12 antibodies for distinguishing epithelioid mesothelioma from adenocarcinoma: identification of a three-antibody immunohistochemical panel with maximal sensitivity and specificity Mod Pathol 19 2006 514 523
29. B. Jiang, G.P. Wu, Y.J. Zhao Transcription expression and clinical significance of TTF-1 mRNA in pleural effusion of patients with lung cancer Diagn Cytopathol 36 2008 849 854
30. Y. Sun, G.P. Wu, C.Q. Fang Diagnostic utility of MOC-31, HBME-1 and MOC-31 mRNA in distinguishing between carcinoma cells and reactive mesothelial cells in pleural effusions Acta Cytol 53 2009 619 624
31. D. Klein Quantification using real-time PCR technology: applications and limitations Trends Mol Med 8 2002 257 260
32. S. Mocellin, C.R. Rossi, P. Pilati Quantitative real-time PCR: a powerful ally in cancer research Trends Mol Med 9 2003 189 195
33. Y. Takuma, K. Nouso, Y. Kobayashi Telomerase reverse transcriptase gene amplification in hepatocellular carcinoma J Gastroenterol Hepatol 19 2004 1300 1304
34. T. Nowak, D. Januszkiewicz, M. Zawada Amplification of hTERT and hTERC genes in leukemic cells with high expression and activity of telomerase Oncol Rep 16 2006 301 305
35. G. Vicidomini, M. Santini, A. Fiorello Intraoperative pleural lavage: is it a valid prognostic factor in lung cancer? Ann Thorac Surg 79 2005 254 257
36. P. Saintigny, S. Coulon, M. Kambouchner Real-time RT-PCR detection of CK19, CK7 and MUC1 mRNA for diagnosis of lymph node micrometastases in non small cell lung carcinoma Int J Cancer 115 2005 777 782
37. Q. Dong, J. Huang, Y. Zhou Hematogenous dissemination of lung cancer cells during surgery: quantitative detection by flow cytometry and prognostic significance Lung Cancer 37 2002 293 301
38. P. Hermanek, R.V. Hutter, L.H. Sobin International Union Against Cancer Classification of isolated tumor cells and micrometastasis Cancer 86 1999 2668 2673