Telomerase reverse transcriptase gene amplification in hepatocellular carcinoma

Journal of Gastroenterology and Hepatology (Australia)

Volumn 19, Issue 11, 2004, Pages 1300-1304

  Takuma, Yoshitaka ^a   Nouso, Kazuhiro ^a   Kobayashi, Yoshiyuki ^a   Nakamura, Shinichiro ^a   Tanaka, Hironori ^a   Matsumoto, Eiji ^a   Fujikawa, Tatsuya ^a   Suzuki, Mayumi ^a   Hanafusa, Tadashi ^a   Shiratori, Yasushi ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

Gene amplification; Hepatocellular carcinoma; Real time polymerase chain reaction; Telomerase reverse transcriptase

Indexed keywords

MESSENGER RNA; TELOMERASE REVERSE TRANSCRIPTASE;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; FEMALE; GENE; GENE AMPLIFICATION; HTERT GENE; HUMAN; HUMAN TISSUE; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; MALE; MALIGNANT TRANSFORMATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

EID: 8344251744     PISSN: 08159319     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1440-1746.2004.03447.x     Document Type: Article

References (25)

1. Stewart SA, Weinberg RA. Telomerase and human tumorigenesis. Semin. Cancer Biol. 2000; 10: 399-406.
2. Takahashi S, Kitamoto M, Takaishi H et al. Expression of telomerase component genes in hepatocellular carcinomas. Eur. J. Cancer 2000; 36: 496-502.
3. Toshikuni N, Nouso K, Higashi T et al. Expression of telomerase- associated protein 1 and telomerase reverse transcriptase in hepatocellular carcinoma. Br. J. Cancer 2000; 82: 833-7.
4. Ducrest AL, Szutorisz H, Lingner J, Nabholz M. Regulation of the human telomerase reverse transcriptase gene. Oncogene 2002; 21: 541-52.
5. Wang J, Xie LY, Allan S, Beach D, Hannon GJ. Myc activates telomerase. Genes Dev. 1998; 12: 1769-74.
6. Kyo S, Takakura M, Kanaya T et al. Estrogen activates telomerase. Cancer Res. 1999; 59: 5917-21.
7. Feitelson MA, Sun B, Satiroglu Tufan NL, Liu J, Pan J, Lian Z. Genetic mechanisms of hepatocarcinogenesis. Oncogene 2002; 21: 2593-604.
8. Bryce LA, Morrison N, Hoare SF, Muir S, Keith WN. Mapping of the gene for the human telomerase reverse transcriptase, hTERT, to chromosome 5p15.33 by fluorescence in situ hybridization. Neoplasia 2000; 2: 197-201.
9. Zhang A, Zheng C, Lindvall C et al. Frequent amplification of the telomerase reverse transcriptase gene in human tumors. Cancer Res. 2000; 60: 6230-5.
10. Zhang A, Zheng C, Hou M et al. Amplification of the telomerase reverse transcriptase (hTERT) gene in cervical carcinomas. Genes Chromosomes Cancer 2002; 34: 269-75.
11. Nouso K, Urabe Y, Higashi T et al. Telomerase as a tool for the differential diagnosis of human hepatocellular carciroma. Cancer 1996; 78: 232-6.
12. Hsieh HF, Harn HJ, Chiu SC, Liu YC, Lui WY, Ho LI. Telomerase activity correlates with cell cycle regulators in human hepatocellular carcinoma. Liver 2000; 20: 143-51.
13. Horikawa I, Barrett JC. cis-Activation of the human telomerase gene (hTERT) by the hepatitis B virus genome. J. Natl Cancer Inst. 2001; 93: 1171-3.
14. Zondervan PE, Wink J, Alers JC et al. Molecular cytogenetic evaluation of virus-associated and non-viral hepatocellular carcinoma: analysis of 26 carcinomas and 12 concurrent dysplasias. J. Pathol. 2000; 192: 207-15.
15. Wong N, Lai P, Lee SW et al. Assessment of genetic changes in hepatocellular carcinoma by comparative genomic hybridization analysis: relationship to disease stage, tumor size, and cirrhosis. Am. J. Pathol. 1999; 154: 37-43.
16. Chen YJ, Yeh SH, Chen JT et al. Chromosomal changes and clonality relationship between primary and recurrent hepatocellular carcinoma. Gastroenterology 2000; 119: 431-40.
17. Wong N, Lai P, Pang E, Leung TW, Lau JW, Johnson PJ. A comprehensive karyotypic study on human hepatocellular carcinoma by spectral karyotyping. Hepatology 2000; 32: 1060-8.
18. Bieche I, Olivi M, Champeme MH, Vidaud D, Lidereau R, Vidaud M. Novel approach to quantitative polymerase chain reaction using real-time detection: application to the detection of gene amplification in breast cancer. Int. J. Cancer 1998; 78: 661-6.
19. Zhang A, Maner S, Betz R et al. Genetic alterations in cervical carcinomas: frequent low-level amplifications of oncogenes are associated with human papillomavirus infection. Int. J. Cancer 2002; 101: 427-33.
20. Bieche I, Franc B, Vidaud D, Vidaud M, Lidereau R. Analyses of MYC, ERBB2, and CCND1 genes in benign and malignant thyroid follicular cell tumors by real-time polymerase chain reaction. Thyroid 2001; 11: 147-52.
21. Saretzki G, Petersen S, Petersen I, Kolble K, von Zglinicki T. hTERT gene dosage correlates with telomerase activity in human lung cancer cell lines. Cancer Lett. 2002; 176: 81-91.
22. Yumoto Y, Hanafusa T, Hada H et al. Loss of heterozygosity and analysis of mutation of p53 in hepatocellular carcinoma. J. Gastroenterol. Hepatol. 1995; 10: 179-85.
23. Tsuda H, Akiyama F, Terasaki H et al. Detection of HER-2/neu (c-erb B-2) DNA amplification in primary breast carcinoma. Interobserver reproducibility and correlation with immunohistochemical HER-2 overexpression. Cancer 2001; 92: 2965-74.
24. Kasai Y, Takeda S, Takagi H. Pathogenesis of hepatocellular carcinoma: a review from the viewpoint of molecular analysis. Semin. Surg. Oncol. 1996; 12: 155-9.
25. Leem SH, Londono-Vallejo JA, Kim JH et al. The human telomerase gene: complete genomic sequence and analysis of tandem repeat polymorphisms in intronic regions. Oncogene 2002; 21: 769-77.