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Volumn 25, Issue 10, 2012, Pages 2227-2235

Mechanisms of toxicity of amorphous silica nanoparticles on human lung submucosal cells in vitro: Protective effects of fisetin

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CATALASE; FISETIN; GELATINASE B; INTERLEUKIN 6; INTERLEUKIN 8; MALONALDEHYDE; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SILICON DIOXIDE;

EID: 84867497797     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx3002884     Document Type: Article
Times cited : (112)

References (40)
  • 2
  • 4
    • 77649146256 scopus 로고    scopus 로고
    • In vivo biodistribution and clearance studies using multimodal organically modified silica nanoparticles
    • Kumar, R., Roy, I., Ohulchanskky, T. Y., Vathy, L. A., Bergey, E. J., Sajjad, M., and Prasad, P. N. (2010) In vivo biodistribution and clearance studies using multimodal organically modified silica nanoparticles ACS Nano 4, 699-708
    • (2010) ACS Nano , vol.4 , pp. 699-708
    • Kumar, R.1    Roy, I.2    Ohulchanskky, T.Y.3    Vathy, L.A.4    Bergey, E.J.5    Sajjad, M.6    Prasad, P.N.7
  • 5
    • 77954063256 scopus 로고    scopus 로고
    • Functional and multifunctional nanoparticles for bioimaging and biosensing
    • Selvan, S. T., Tan, T. T., Yi, D. K., and Jana, N. R. (2010) Functional and multifunctional nanoparticles for bioimaging and biosensing Langmuir 26, 11631-11641
    • (2010) Langmuir , vol.26 , pp. 11631-11641
    • Selvan, S.T.1    Tan, T.T.2    Yi, D.K.3    Jana, N.R.4
  • 6
    • 84858998451 scopus 로고    scopus 로고
    • The toxicological mode of action and the safety of synthetic amorphous silica-a nanostructured material
    • Fruijtier-Pölloth, C. (2012) The toxicological mode of action and the safety of synthetic amorphous silica-a nanostructured material Toxicology 294, 61-79
    • (2012) Toxicology , vol.294 , pp. 61-79
    • Fruijtier-Pölloth, C.1
  • 7
    • 33845218637 scopus 로고    scopus 로고
    • In vitro toxicity of silica nanoparticles in human lung cancer cells
    • Lin, W, Huang, Y. W., Zhou, X. D., and Ma, Y. (2006) In vitro toxicity of silica nanoparticles in human lung cancer cells Toxicol. Appl. Pharmacol. 217, 252-259
    • (2006) Toxicol. Appl. Pharmacol. , vol.217 , pp. 252-259
    • Lin, W.1    Huang, Y.W.2    Zhou, X.D.3    Ma, Y.4
  • 8
    • 70349394917 scopus 로고    scopus 로고
    • Oxidative stress of silica nanoparticles in human bronchial epithelial cell, Beas-2B
    • Eom, H. J. and Choi, J. (2009) Oxidative stress of silica nanoparticles in human bronchial epithelial cell, Beas-2B Toxicol. in Vitro 23, 1326-1332
    • (2009) Toxicol. in Vitro , vol.23 , pp. 1326-1332
    • Eom, H.J.1    Choi, J.2
  • 9
    • 84876059352 scopus 로고    scopus 로고
    • Screening of different metal oxide nanoparticles reveals selective toxicity and inflammatory potential of silica nanoparticles in lung epithelial cells and macrophages
    • Epub ahead of print
    • Panas, A., Marquardt, C., Nalcaci, O., Bockhorn, H., Baumann, W., Paur, H. R., Mülhopt, S., Diabaté, S., and Weiss, C. (2012) Screening of different metal oxide nanoparticles reveals selective toxicity And inflammatory potential of silica nanoparticles in lung epithelial cells and macrophages. Nanotoxicology, Epub ahead of print.
    • (2012) Nanotoxicology
    • Panas, A.1    Marquardt, C.2    Nalcaci, O.3    Bockhorn, H.4    Baumann, W.5    Paur, H.R.6    Mülhopt, S.7    Diabaté, S.8    Weiss, C.9
  • 12
    • 33846785537 scopus 로고    scopus 로고
    • Matrix Metalloproteinases in Lung: Multiple Multifarious and Multifaceted
    • Greenlee, K. J., Werb, Z., and Kheradmand, F. (2007) Matrix Metalloproteinases in Lung: Multiple Multifarious and Multifaceted Physiol. Rev. 87, 69-98
    • (2007) Physiol. Rev. , vol.87 , pp. 69-98
    • Greenlee, K.J.1    Werb, Z.2    Kheradmand, F.3
  • 13
    • 0032736565 scopus 로고    scopus 로고
    • Inhibition of matrix metalloproteinase MMP-2 activates chloride current in human airway epithelial cells
    • Duszyk, M., Shu, Y., Sawicki, G., Radomski, A., Man, S. F., and Radomski, M. W. (1999) Inhibition of matrix metalloproteinase MMP-2 activates chloride current in human airway epithelial cells Can. J. Physiol. Pharmacol. 77, 529-535
    • (1999) Can. J. Physiol. Pharmacol. , vol.77 , pp. 529-535
    • Duszyk, M.1    Shu, Y.2    Sawicki, G.3    Radomski, A.4    Man, S.F.5    Radomski, M.W.6
  • 14
    • 80455173408 scopus 로고    scopus 로고
    • Polystyrene nanoparticles activate ion transport in human airway epithelial cells
    • McCarthy, J., Gong, X., Nahirney, D., Duszyk, M., and Radomski, M. (2011) Polystyrene nanoparticles activate ion transport in human airway epithelial cells Int. J. Nanomed. 6, 1343-1356
    • (2011) Int. J. Nanomed. , vol.6 , pp. 1343-1356
    • McCarthy, J.1    Gong, X.2    Nahirney, D.3    Duszyk, M.4    Radomski, M.5
  • 15
    • 79251576161 scopus 로고    scopus 로고
    • Inflammatory and cytotoxic responses of an alveolar-capillary coculture model to silica nanoparticles: Comparison with conventional monocultures
    • Kasper, J., Hermanns, M. I., Bantz, C., Maskos, M., Stauber, R., Pohl, C., and Unger, R. E. (2011) Inflammatory and cytotoxic responses of an alveolar-capillary coculture model to silica nanoparticles: Comparison with conventional monocultures Part. Fibre Toxicol. 8, 6
    • (2011) Part. Fibre Toxicol. , vol.8 , pp. 6
    • Kasper, J.1    Hermanns, M.I.2    Bantz, C.3    Maskos, M.4    Stauber, R.5    Pohl, C.6    Unger, R.E.7
  • 16
    • 67649370750 scopus 로고    scopus 로고
    • Oxidative Stress contributes to silica nanoparticle-induced cytotoxicity in human embryonic kidney cells
    • Wang, F., Gao, F., Lan, M., Yuan, H., Huang, Y., and Liu, J. (2009) Oxidative Stress contributes to silica nanoparticle-induced cytotoxicity in human embryonic kidney cells Toxicol. in Vitro 23, 808-815
    • (2009) Toxicol. in Vitro , vol.23 , pp. 808-815
    • Wang, F.1    Gao, F.2    Lan, M.3    Yuan, H.4    Huang, Y.5    Liu, J.6
  • 17
    • 84858860290 scopus 로고    scopus 로고
    • Effects of SiO(2) nanoparticles on HFL-I activating ROS-mediated apoptosis via p53 pathway
    • Xu, Z., Chou, L., and Sun, J. (2012) Effects of SiO(2) nanoparticles on HFL-I activating ROS-mediated apoptosis via p53 pathway J. Appl. Toxicol. 32, 358-364
    • (2012) J. Appl. Toxicol. , vol.32 , pp. 358-364
    • Xu, Z.1    Chou, L.2    Sun, J.3
  • 18
    • 77649179574 scopus 로고    scopus 로고
    • Nano-SiO2 induces apoptosis via activation of p53 and Bax mediated by oxidative stress in human hepatic cell line
    • Ye, Y., Liu, J., Xu, J., Sun, L., Chen, M., and Lan, M. (2010) Nano-SiO2 induces apoptosis via activation of p53 and Bax mediated by oxidative stress in human hepatic cell line Toxicol. in Vitro 24, 751-758
    • (2010) Toxicol. in Vitro , vol.24 , pp. 751-758
    • Ye, Y.1    Liu, J.2    Xu, J.3    Sun, L.4    Chen, M.5    Lan, M.6
  • 20
    • 84861715726 scopus 로고    scopus 로고
    • Amorphous silica Nanoparticles trigger nitric oxide/peroxynitrite imbalance in human endothelial cells: Inflammatory and cytotoxic effects
    • Corbalan, J. J., Medina, C., Jacoby, A., Malinski, T., and Radomski, M. W. (2011) Amorphous silica Nanoparticles trigger nitric oxide/peroxynitrite imbalance in human endothelial cells: Inflammatory and cytotoxic effects Int. J. Nanomed. 6, 2821-2835
    • (2011) Int. J. Nanomed. , vol.6 , pp. 2821-2835
    • Corbalan, J.J.1    Medina, C.2    Jacoby, A.3    Malinski, T.4    Radomski, M.W.5
  • 21
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak, K. J. and Schmittgen, T. D. (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method Methods 25, 402-408
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 23
    • 84862893488 scopus 로고    scopus 로고
    • The role of reactive oxygen species in silicon dioxide nanoparticle-induced cytotoxicity and DNA damage in HaCaT cells
    • Gong, C., Tao, G., Yang, L., Liu, J., He, H., and Zhuang, Z. (2012) The role of reactive oxygen species in silicon dioxide nanoparticle-induced cytotoxicity and DNA damage in HaCaT cells Mol. Biol. Rep. 39, 4915-4925
    • (2012) Mol. Biol. Rep. , vol.39 , pp. 4915-4925
    • Gong, C.1    Tao, G.2    Yang, L.3    Liu, J.4    He, H.5    Zhuang, Z.6
  • 24
    • 80052092114 scopus 로고    scopus 로고
    • The cytotoxic activity of amorphous silica nanoparticles is mainly influenced by surface area and not by aggregation
    • Rabolli, V., Thomassen, L. C., Uwambayinema, F., Martens, J. A., and Lison, D. (2011) The cytotoxic activity of amorphous silica nanoparticles is mainly influenced by surface area and not by aggregation Toxicol. Lett. 206, 197-203
    • (2011) Toxicol. Lett. , vol.206 , pp. 197-203
    • Rabolli, V.1    Thomassen, L.C.2    Uwambayinema, F.3    Martens, J.A.4    Lison, D.5
  • 25
    • 18344416789 scopus 로고    scopus 로고
    • NF-κB, a pivotal transcription factor in silica-induced diseases
    • Chen, F. and Shi, X. (2002) NF-κB, a pivotal transcription factor in silica-induced diseases Mol. Cell. Biochem. 234-235, 169-176
    • (2002) Mol. Cell. Biochem. , vol.234-235 , pp. 169-176
    • Chen, F.1    Shi, X.2
  • 26
    • 77956161513 scopus 로고    scopus 로고
    • Endothelial cells dysfunction induced by silica nanoparticles through oxidative stress via JNK/P53 and NF-KappaB pathways
    • Liu, X. and Sun, J. (2010) Endothelial cells dysfunction induced by silica nanoparticles through oxidative stress via JNK/P53 and NF-KappaB pathways Biomaterials 31, 8198-8209
    • (2010) Biomaterials , vol.31 , pp. 8198-8209
    • Liu, X.1    Sun, J.2
  • 27
    • 0030771914 scopus 로고    scopus 로고
    • Lipid peroxidation is involved in the activation of NF-kappaB by tumor necrosis factor but not interleukin-1 in the human endothelial cell line ECV304. Lack of involvement of H2O2 in NF-kappaB activation by either cytokine in both primary and transformed endothelial cells
    • Bowie, A. G., Moynagh, P. N., and O'Neill, L. A. (1997) Lipid peroxidation is involved in the activation of NF-kappaB by tumor necrosis factor but not interleukin-1 in the human endothelial cell line ECV304. Lack of involvement of H2O2 in NF-kappaB activation by either cytokine in both primary and transformed endothelial cells J. Biol. Chem. 272, 25941-25950
    • (1997) J. Biol. Chem. , vol.272 , pp. 25941-25950
    • Bowie, A.G.1    Moynagh, P.N.2    O'Neill, L.A.3
  • 29
    • 21044451701 scopus 로고    scopus 로고
    • Amorphous silica particles promote inflammatory gene expression through the redox sensitive transcription factor, AP-1, in alveolar epithelial cells
    • Singal, M. and Finkelstein, J. N. (2005) Amorphous silica particles promote inflammatory gene expression through the redox sensitive transcription factor, AP-1, in alveolar epithelial cells Exp. Lung Res. 31, 581-597
    • (2005) Exp. Lung Res. , vol.31 , pp. 581-597
    • Singal, M.1    Finkelstein, J.N.2
  • 30
    • 0031738172 scopus 로고    scopus 로고
    • Regulation of Matrix Metalloproteinases (MMP-2, -3, -9, and -13) by Interleukin-1 and Interleukin-6 in Mouse Calvaria: Association of MMP Induction with Bone Resorption
    • Kusano, K., Miyaura, C., Inada, M., Tamura, T., Ito, A., Nagase, H., Kamoi, K., and Suda, T. (1998) Regulation of Matrix Metalloproteinases (MMP-2, -3, -9, and -13) by Interleukin-1 and Interleukin-6 in Mouse Calvaria: Association of MMP Induction with Bone Resorption Endocrinology 139, 1338-1345
    • (1998) Endocrinology , vol.139 , pp. 1338-1345
    • Kusano, K.1    Miyaura, C.2    Inada, M.3    Tamura, T.4    Ito, A.5    Nagase, H.6    Kamoi, K.7    Suda, T.8
  • 32
    • 0008589879 scopus 로고    scopus 로고
    • Japanese intake of flavonoids and Isoflavonoids from foods
    • Kimira, M., Arai, Y., Shimoi, K., and Watanabe, S. (1998) Japanese intake of flavonoids and Isoflavonoids from foods J. Epidemiol. 8, 168-175
    • (1998) J. Epidemiol. , vol.8 , pp. 168-175
    • Kimira, M.1    Arai, Y.2    Shimoi, K.3    Watanabe, S.4
  • 33
    • 0033637140 scopus 로고    scopus 로고
    • The effects of plant flavonoids on mammalian cells: Implications for inflammation, heart disease, and cancer
    • Middleton, E., Jr., Kandaswami, C., and Theoharides, T. C. (2000) The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer Pharmacol. Rev. 52, 673-751
    • (2000) Pharmacol. Rev. , vol.52 , pp. 673-751
    • Middleton, Jr.E.1    Kandaswami, C.2    Theoharides, T.C.3
  • 34
    • 84857786880 scopus 로고    scopus 로고
    • Fisetin, a bioactive flavonol, attenuates allergic airway inflammation through negative regulation of NF-κB
    • Goh, F. Y., Upton, N., Guan, S., Cheng, C., Shanmugam, M. K., Sethi, G., Leung, B. P., and Wong, W. S. (2012) Fisetin, a bioactive flavonol, attenuates allergic airway inflammation through negative regulation of NF-κB Eur. J. Pharmacol. 679, 109-116
    • (2012) Eur. J. Pharmacol. , vol.679 , pp. 109-116
    • Goh, F.Y.1    Upton, N.2    Guan, S.3    Cheng, C.4    Shanmugam, M.K.5    Sethi, G.6    Leung, B.P.7    Wong, W.S.8
  • 35
    • 84857966307 scopus 로고    scopus 로고
    • Fisetin prevents fluoride- and dexamethasone-induced oxidative damage in osteoblast and hippocampal cells
    • Inkielewicz-Stepniak, I., Radomski, M. W., and Wozniak, M. (2012) Fisetin prevents fluoride- and dexamethasone-induced oxidative damage in osteoblast and hippocampal cells Food Chem. Toxicol. 50, 583-589
    • (2012) Food Chem. Toxicol. , vol.50 , pp. 583-589
    • Inkielewicz-Stepniak, I.1    Radomski, M.W.2    Wozniak, M.3
  • 37
    • 55749091647 scopus 로고    scopus 로고
    • Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts
    • Lundqvist, M., Stigler, J., Elia, G., Lynch, I., Cedervall, T., and Dawson, K. A. (2008) Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts Proc. Natl. Acad. Sci. U.S.A. 105, 14265-14270
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 14265-14270
    • Lundqvist, M.1    Stigler, J.2    Elia, G.3    Lynch, I.4    Cedervall, T.5    Dawson, K.A.6
  • 38
    • 24344499139 scopus 로고    scopus 로고
    • Hydrogen peroxide regulation of endothelial function: Origins, mechanisms, and consequences
    • Cai, H. (2005) Hydrogen peroxide regulation of endothelial function: Origins, mechanisms, and consequences Cardiovasc. Res. 68, 26-36
    • (2005) Cardiovasc. Res. , vol.68 , pp. 26-36
    • Cai, H.1
  • 39
    • 0037230810 scopus 로고    scopus 로고
    • Nitric oxide, platelet function, myocardial infarction and reperfusion therapies
    • Alonso, D. and Radomski, M. W. (2005) Nitric oxide, platelet function, myocardial infarction and reperfusion therapies Heart Fail. Rev. 8, 47-54
    • (2005) Heart Fail. Rev. , vol.8 , pp. 47-54
    • Alonso, D.1    Radomski, M.W.2
  • 40
    • 77955048966 scopus 로고    scopus 로고
    • Methods for detection and measurement of hydrogen peroxide inside and outside of cells
    • Rhee, S. G., Chang, T. S., Jeong, W., and Kang, D. (2010) Methods for detection and measurement of hydrogen peroxide inside and outside of cells Mol. Cells 29, 539-549
    • (2010) Mol. Cells , vol.29 , pp. 539-549
    • Rhee, S.G.1    Chang, T.S.2    Jeong, W.3    Kang, D.4


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