Effects of SiO 2 nanoparticles on HFL-I activating ROS-mediated apoptosis via p53 pathway

Journal of Applied Toxicology

Volumn 32, Issue 5, 2012, Pages 358-364

  Xu, Zhengli ^a,b,c   Chou, Laisheng ^d   Sun, Jiao ^a,b,c  

^a Shanghai Biomaterials Research and Testing Center   (China)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c Shanghai Key Laboratory of Stomatology   (China)

^d BOSTON UNIVERSITY   (United States)

Author keywords

Apoptosis; Chondriosome; P53; Reactive oxygen species (ROS); SiO 2 nanoparticles

Indexed keywords

CASPASE 9; CYTOCHROME C; NANOPARTICLE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SILICON DIOXIDE;

APOPTOSIS; ARTICLE; CELL DAMAGE; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LUNG FIBROBLAST; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION; CELL LINE; CELL SURVIVAL; CYTOLOGY; DRUG EFFECT; FIBROBLAST; METABOLISM; PATHOLOGY;

APOPTOSIS; CELL LINE; CELL SURVIVAL; FIBROBLASTS; HUMANS; NANOPARTICLES; REACTIVE OXYGEN SPECIES; SILICON DIOXIDE; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

EID: 84858860290     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.1710     Document Type: Article

References (27)

1. AshaRani PV, Low Kah Mun G, Hande MP, Valiyaveettil S. 2009. Cytotoxicity and genotoxicity of silver nanoparticles in human cells. ACS Nano. 3: 279-290.
2. Chen B, Cheng J, Shen M, Gao F, Xu W, Shen H, Ding J, Gao C, Sun Q, Sun X, Cheng H, Li G, Chen W, Chen N, Liu L, Li X, Wang X. 2009. Magnetic nanoparticle of Fe3O4 and 5-bromotetrandrin interact synergistically to induce apoptosis by daunorubicin in leukemia cells. Int. J. Nanomed. 4: 65-71.
3. Chen YH, Lin SJ, Ku HH, Shiao MS, Lin FY, Chen JW, Chen YL. 2001. Salvianolic acid B attenuates VCAM-1 and ICAM-1 expression in TNF-alpha-treated human aortic endothelial cells. J. Cell. Biochem. 82: 512-521.
4. Chipuk JE, Kuwana T, Bouchier-Hayes L, Droin NM, Newmeyer DD, Schuler M, Green DR. 2004. Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis. Science 303: 1010-1014.
5. Dimmeler S, Zeiher AM. 2000. Reactive oxygen species and vascular cell apoptosis in response to angiotensin II and pro-atherosclerotic factors. Regul. Pept. 90: 19-25.
6. Gao CF, Ren S, Zhang L, Nakajima T, Ichinose S, Hara T, Koike K, Tsuchida N. 2001. Caspase-dependent cytosolic release of cytochrome c and membrane translocation of Bax in p53-induced apoptosis. Exp. Cell Res. 265: 145-151.
7. Garrido C GL, Brunet M, Puig PE, Didelot C, Kroemer G. 2006. Mechanisms of cyt C release from mitochondria. Cell Death Differ. 13: 1423-1433.
8. Grandjean-Laquerriere A, Laquerriere P, Laurent-Maquin D, Guenounou M, Phillips TM. 2004. The effect of the physical characteristics of hydroxyapatite particles on human monocytes IL-18 production in vitro. Biomaterials 25: 5921-5927.
9. Hirsch LR, Stafford RJ, Bankson JA, Sershen SR, Rivera B, Price RE, Hazle JD, Halas NJ, West JL. 2003. Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance. Proc. Natl. Acad. Sci. USA 100: 13549-13554.
10. Hollander MC, Alamo I, Jackman J, Wang MG, McBride OW, Fornace AJ Jr. 1993. Analysis of the mammalian gadd45 gene and its response to DNA damage. J. Biol. Chem. 268: 24385-24393.
11. Huo Q, Liu J, Wang LQ, Jiang Y, Lambert TN, Fang E. 2006. A new class of silica cross-linked micellar core-shell nanoparticles. J. Am. Chem. Soc. 128: 6447-6453.
12. Iezzi EB, Duchamp JC, Harich K, Glass TE, Lee HM, Olmstead MM, Balch AL, Dorn HC. 2002. A symmetric derivative of the trimetallic nitride endohedral metallofullerene, Sc3N@C80. J. Am. Chem. Soc. 124: 524-525.
13. Laquerriere P, Grandjean-Laquerriere A, Jallot E, Balossier G, Frayssinet P, Guenounou M. 2003. Importance of hydroxyapatite particles characteristics on cytokines production by human monocytes in vitro. Biomaterials 24: 2739-2747.
14. Maynard AD, Aitken RJ, Butz T, Colvin V, Donaldson K, Oberdorster G, Philbert MA, Ryan J, Seaton A, Stone V, Tinkle SS, Tran L, Walker NJ, Warheit DB. 2006. Safe handling of nanotechnology. Nature 444: 267-269.
15. Myashita TRJ. 1995. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 80: 293-299.
16. Nakano K, Vousden KH. 2001. PUMA, a novel proapoptotic gene, is induced by p53. Mol. Cell 7: 683-694.
17. Napierska D, Thomassen LC, Rabolli V, Lison D, Gonzalez L, Kirsch-Volders M, Martens JA, Hoet PH. 2009. Size-dependent cytotoxicity of monodisperse silica nanoparticles in human endothelial cells. Small 5: 846-853.
18. Oda E, Ohki R, Murasawa H, Nemoto J, Shibue T, Yamashita T, Tokino T, Taniguchi T, Tanaka N. 2000. Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. Science 288: 1053-1058.
19. Roy I, Ohulchanskyy TY, Bharali DJ, Pudavar HE, Mistretta RA, Kaur N, Prasad PN. 2005. Optical tracking of organically modified silica nanoparticles as DNA carriers: a nonviral, nanomedicine approach for gene delivery. Proc. Natl. Acad. Sci. USA 102: 279-284.
20. Simbula G, Columbano A, Ledda-Columbano GM, Sanna L, Deidda M, Diana A, Pibiri M. 2007. Increased ROS generation and p53 activation in alpha-lipoic acid-induced apoptosis of hepatoma cells. Apoptosis 12: 113-123.
21. Slowing, II, Trewyn BG, Lin VS. 2007. Mesoporous silica nanoparticles for intracellular delivery of membrane-impermeable proteins. J. Am. Chem. Soc. 129: 8845-8849.
22. Sun J, Ding T. 2009. p53 reaction to apoptosis induced by hydroxyapatite nanoparticles in rat macrophages. J. Biomed. Mater. Res. A 88: 673-679.
23. Thornborrow EC, Manfredi JJ. 2001. The tumor suppressor protein p53 requires a cofactor to activate transcriptionally the human BAX promoter. J. Biol. Chem. 276: 15598-15608.
24. Tsuji JS, Maynard AD, Howard PC, James JT, Lam CW, Warheit DB, Santamaria AB. 2006. Research strategies for safety evaluation of nanomaterials, part IV: risk assessment of nanoparticles. Toxicol. Sci. 89: 42-50.
25. Yang J, Lee J, Kang J, Lee K, Suh JS, Yoon HG, Huh YM, Haam S. 2008. Hollow silica nanocontainers as drug delivery vehicles. Langmuir 24: 3417-3421.
26. Yuan Y, Liu C, Qian J, Wang J, Zhang Y. 2010. Size-mediated cytotoxicity and apoptosis of hydroxyapatite nanoparticles in human hepatoma HepG2 cells. Biomaterials 31: 730-740.
27. Zhao X, Hilliard LR, Mechery SJ, Wang Y, Bagwe RP, Jin S, Tan W. 2004. A rapid bioassay for single bacterial cell quantitation using bioconjugated nanoparticles. Proc. Natl. Acad. Sci. USA 101: 15027-15032.