Effect of an aqueous extract of Cucurbita ficifolia Bouché on the glutathione redox cycle in mice with STZ-induced diabetes

Journal of Ethnopharmacology

Volumn 144, Issue 1, 2012, Pages 101-108

  Diaz Flores M ^a   Angeles Mejia, S ^a   Baiza Gutman, L A ^c   Medina Navarro, R ^d   Hernandez Saavedra D ^a   Ortega Camarillo, C ^a   Roman Ramos, R ^b   Cruz, M ^a   Alarcon Aguilar, F J ^b  

^a HOSPITAL DE ESPECIALIDADES   (Mexico)

^b UNIVERSIDAD AUTÓNOMA METROPOLITANA   (Mexico)

^c UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^d Departamento de Metabolismo Experimental   (Mexico)

Author keywords

Cucurbita ficifolia; Diabetes mellitus; Glutathione redox cycle; Lipid peroxidation; Oxidative stress

Indexed keywords

ANTIDIABETIC AGENT; CUCURBITA FICIFOLIA EXTRACT; GLUCOSE; GLUTATHIONE DISULFIDE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; HEMOGLOBIN A1C; PLANT EXTRACT; STREPTOZOCIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; ARTICLE; CONTROLLED STUDY; CUCURBITA FICIFOLIA; GLUCOSE BLOOD LEVEL; HEART; HYPERPHAGIA; KIDNEY; LIPID PEROXIDATION; LIVER HOMOGENATE; MALE; MEDICINAL PLANT; MOUSE; NONHUMAN; OXIDATIVE STRESS; PANCREAS; POLYDIPSIA; STREPTOZOCIN DIABETES; TISSUE HOMOGENATE; TREATMENT DURATION;

ANIMALS; CUCURBITA; DIABETES MELLITUS, EXPERIMENTAL; FRUIT; GLUTATHIONE; GLUTATHIONE DISULFIDE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; HYPOGLYCEMIC AGENTS; KIDNEY; LIPID PEROXIDATION; LIVER; MALE; MEDICINE, TRADITIONAL; MICE; MYOCARDIUM; OXIDATION-REDUCTION; PANCRELIPASE; PLANT EXTRACTS;

CUCURBITA FICIFOLIA; MUS;

EID: 84867491369     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2012.08.036     Document Type: Article

References (45)

1. J.L. Acosta-Patiño, E. Jiménez-Balderas, M.A. Juárez-Oropeza, and J.C. Díaz-Zagoya Hypoglycemic action of Cucurbita ficifolia on type 2 diabetic patients with moderately high blood glucose levels Journal of Ethnopharmacology 77 2001 99 101
2. F.J. Alarcon-Aguilar, E. Hernandez-Galicia, A.E. Campos-Sepulveda, S. Xolalpa-Molina, J.F. Rivas-Vilchis, L.I. Vazquez-Carrillo, and R. Roman-Ramos Evaluation of the hypoglycemic effect of Cucurbita ficifolia Bouché (Cucurbitaceae) in different experimental models Journal of Ethnopharmacology 82 2002 185 189
3. D.A. Allen, S. Harwood, M. Varagunam, M.J. Raftery, and M.M. Yaqoob High glucose-induced oxidative stress causes apoptosis in proximal tubular epithelial cells and is mediated by multiple caspases FASEB Journal 17 2003 908 910
4. A. Andrade-Cetto, and M. Heinrich Mexican plants with hypoglycaemic effect used in the treatment of diabetes Journal of Ethnopharmacology 99 2005 325 348
5. N. Ballatori, S.M. Krance, S. Notenboom, S. Shi, K. Tieu, and C.L. Hammond Glutathione dysregulation and the etiology and progression of human diseases Biological Chemistry 390 2009 191 214
6. N. Bashan, J. Kovsan, I. Kachko, H. Ovadia, and A. Rudich Positive and negative regulation of insulin signaling by reactive oxygen and nitrogen species Physiological Reviews 89 2009 27 71
7. E. Beutler Effect of flavin compounds on glutathione reductase activity: in vivo and in vitro studies Journal of Clinical Investigation 48 1969 1957 1966
8. M. Brownlee Biochemistry and molecular cell biology of diabetic complications Nature 414 2001 813 820
9. M.A. Catherwood, L.A. Powell, P. Anderson, D. McMaster, P.C. Sharpe, and E.R. Trimble Glucose-induced oxidative stress in mesangial cells Kidney International 61 2002 599 608
10. F. Comelli, I. Bettoni, M. Colleoni, G. Giagnoni, and B. Costa Beneficial effects of a Cannabis sativa extract treatment on diabetes-induced neuropathy and oxidative stress Phytotherapy Research 23 2009 1678 1684
11. M.M. Dallak, D.P. Mikhailidis, M.A. Haidara, I.M. Bin-Jaliah, O.M. Tork, M.A. Rateb, H.Z. Yassin, Z.A. Al-Refaie, I.M. Ibrahim, S.M. Elawa, L.A. Rashed, and N.A. Afifi Oxidative stress as a common mediator for apoptosis induced-cardiac damage in diabetic rats The Open Cardiovascular Medicine Journal 2 2008 70 78
12. M. Díaz-Flores, M.A. Ibáñez-Hernández, R.E. Galván, M. Gutiérrez, G. Durán-Reyes, R. Medina-Navarro, D. Pascoe-Lira, C. Ortega-Camarillo, C. Vilar-Rojas, M. Cruz, and L.A. Baiza-Gutman Glucose-6-phosphate dehydrogenase activity and NADPH/NADP ratio in liver and pancreas are dependent on the severity of hyperglycemia in rat Life Sciences 78 2006 2601 2607
13. Y. Dincer, T. Akcay, Z. Alademir, and H. Ilkova Effect of oxidative stress on glutathione pathway in red blood cells from patients with insulin-dependent diabetes mellitus Metabolism 51 2002 1360 1362
14. W. Dröge Free radicals in the physiological control of cell function Physiological Reviews 82 2002 47 95
15. K. Fujisawa, T. Nishikawa, D. Kukidome, K. Imoto, T. Yamashiro, H. Motoshima, T. Matsumura, and E. Araki TZDs reduce mitocondrial ROS production and enhance mitocondrial biogenesis Biochemical and Biophysical Research Communications 379 2009 43 48
16. J. Hunt, C. Smith, and S.P. Wolf Autoxidative glycosylation and possible involvement of preoxides and free radicals in LDL modification by glucose Diabetes 39 1990 1420 1424
17. A.M. Jentzsch, H. Bachmann, P. Fürst, and H.K. Biesalski Improved analysis of malondialdehyde in human body fluids Free Radical Biology and Medicine 20 1996 251 256
18. S.R. Jiao, B. Wang, C.Y. Huang, S. Yu, and W.Y. Yin A diabetic model for liver oxidant damage in mice Journal of Hygiene Research 41 2007 115 118
19. R.A. Lawrence, and R.F. Burk Glutathione peroxidase activity in selenium-deficient rat liver Biochemical and Biophysical Research Communications 71 1976 952 958
20. C.J. Li, Q.M. Zhang, M.Z. Li, J.Y. Zhang, P. Yu, and D.M. Yu Attenuation of myocardial apoptosis by alpha-lipoic acid through suppression of mitochondrial oxidative stress to reduce diabetic cardiomyopathy Chinese Medical Journal 122 2009 2580 2586
21. O.H. Lowry, N.J. Rosebrough, A.L. Farr, and R.J. Randall Protein measurement with the Folin phenol reagent The Journal of Biological Chemistry 193 1951 265 275
22. A.C. Maritim, R.A. Sanders, and J.B. Watkins 3rd Effects of alpha-lipoic acid on biomarkers of oxidative stress in streptozotocin-induced diabetic rats The Journal of Nutritional Biochemistry 14 2003 288 294
23. K. Murakami, T. Kondo, Y. Ohtsuka, Y. Fujiwara, M. Shimada, and Y. Kawakami Impairment of glutathione metabolism in erythrocytes from patients with diabetes mellitus Metabolism 38 1989 753 758
24. I.G. Obrosova, L. Fathallah, and D.A. Greene Early changes in lipid peroxidation and antioxidative defense in diabetic rat retina: effect of DL-alpha-lipoic acid European Journal Pharmacology 398 2000 139 146
25. R. Roman-Ramos, S.J.L. Flores, H.G. Partida, L.A. Lara, and F.J. Alarcon-Aguilar Experimental study of the hypoglycaemic effects of some antidiabetic plant Archives of Medical Research 22 1991 87 93
26. R. Roman-Ramos, L.A. Lara, F.J. Alarcon-Aguilar, and S.J.L. Flores Hypoglycemic activity of some antidiabetic plants Archives of Medical Research 23 1992 105 109
27. R. Roman-Ramos, J.L. Flores-Saenz, and F.J. Alarcon-Aguilar Anti-hyperglycemic effect of some edible plants Journal of Ethnopharmacology 48 1995 25 32
28. R. Roman-Ramos, J.C. Almanza-Perez, A. Fortis-Barrera, S. Angeles-Mejia, T.R. Banderas-Dorantes, A. Zamilpa-Alvarez, M. Diaz-Flores, I. Jasso, G. Blancas-Flores, J. Gomez, and F.J. Alarcon-Aguilar Antioxidant and anti-inflammatory effects of a hypoglycemic fraction from Cucurbita ficifolia Bouché in streptozotocin-induced diabetes mice The American Journal of Chinese Medicine 40 2012 1 14
29. J.W. Russell, D. Golovoy, A.M. Vincent, P. Mahendru, J.A. Olzmann, A. Mentzer, and E.L. Feldman High glucose induced oxidative stress and mitochondrial dysfunction in neurons FASEB Journal 16 2002 1738 1748
30. F.Q. Schafer, and G.R. Buettner Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple Free Radical Biology and Medicine 30 2001 1191 1212
31. V. Serru, M. Baudin, F. Ziegler, J.P. David, M.J. Cals, M. Vaubourdolle, and N. Mario Quantification of reduced and oxidized glutathione in whole blood samples by capillary electrophoresis Clinical Chemistry 47 2001 1321 1324
32. N. Sharma, and V. Garg Antidiabetic and antioxidant potential of ethanolic extract of Butea monosperma leaves in alloxan-induced diabetic mice Indian Journal of Biochemistry and Biophysics 46 2009 99 105
33. R.S. Sohal, H.H. Ku, S. Agarwal, M.J. Forster, and H. Lal Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse Mechanisms of ageing and development 74 1994 121 133
34. F. Tietze Enzymatic method for quantitative determination of nanogram amounts of total an oxidized glutathione Analytical Biochemistry 27 1969 502 522
35. Y. Urata, H. Yamamoto, S. Goto, H. Tsushima, S. Akazawa, S. Yamashita, S. Nagataki, and T. Kondo Long exposure to high glucose concentration impairs the responsive expression of gamma-glutamylcysteine synthetase by interleukin-1beta and tumor necrosis factor-alpha in mouse endothelial cells The Journal of Biological Chemistry 271 1996 15146 15152
36. A.M. Vincent, J.W. Russell, P. Low, and E.L. Feldman Oxidative stress in the pathogenesis of diabetic neuropathy Endocrine Reviews 25 2004 612 628
37. S.P. Wolff, and R.T. Dean Glucose autoxidation and protein modification the potential role of autoxidative glycosylation in diabetes The Biochemical Journal 245 1987 243 250
38. L. Wu, W. Nicholson, S.M. Knobel, R.J. Steffner, J.M. May, D.W. Piston, and A.C. Powers Oxidative stress is a mediator of glucose toxicity in insulin-secreting pancreatic islet cell lines Journal of Biological Chemistry 279 2004 12126 12134
39. T. Xia, and Q. Wang Antihyperglycemic effect of Cucurbita ficifolia fruit extract in streptozotocin-induced diabetic rats Fitoterapia 77 2006 530 533
40. T. Xia, and Q. Wang d-chiro-inositol found in Cucurbita ficifolia (Cucurbitaceae) fruit extracts plays the hypoglycaemic role in streptozocin-diabetic rats Journal of Pharmacy and Pharmacology 58 2006 1527 1532
41. T. Xia, and Q. Wang Hypoglycaemic role of Cucurbita ficifolia (Cucurbitaceae) fruit extract in streptozotocin-induced diabetic rats Journal of the Science of Food and Agriculture 87 2007 1753 1757
42. T. Xia, and Q. Wang Effect of Cucurbita ficifolia fruit extract on lipid profile and oral glucose tolerance in streptozotocin-induced diabetic rats Journal of Food Biochemistry 33 2009 416 424
43. Y. Xu, B.W. Osborne, and R.C. Stanton Diabetes causes inhibition of glucose-6-phosphate dehydrogenase via activation of PKA, which contributes to oxidative stress in rat kidney cortex American Journal of Physiology - Renal Physiology 289 2005 F1040 F1047
44. Z. Xu, K.P. Patel, M.F. Lou, and G.J. Rozanski Up-regulation of K channels in diabetic rat ventricular myocytes by insulin and glutathione Cardiovascular Research 53 2002 80 88
45. W.H. Yang, S.Y. Park, S. Ji, J.G. Kang, J.E. Kim, H. Song, I. Mook-Jung, K.M. Choe, and J.W. Cho O-GlcNAcylation regulates hyperglycemia-induced GPX1 activation Biochemical and Biophysical Research Communications 391 2010 756 761