Roles of inflammation in cancer initiation, progression, and metastasis

Frontiers in Bioscience - Scholar

Volumn 2 S, Issue 1, 2010, Pages 176-183

  Rajput, Sandeep ^a   Wilber, Andrew ^a,b  

^a Immunology and Cell Biology   (United States)

^b SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cancer; Cytokines; Growth factors; Immune cells; Inflammation; Review; Tumor microenvironment

Indexed keywords

CYTOKINE; HYPOXIA INDUCIBLE FACTOR 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; PROSTAGLANDIN SYNTHASE;

ARTICLE; DISEASE COURSE; DRUG DELIVERY SYSTEM; HUMAN; INFLAMMATION; METABOLISM; METASTASIS; NEOPLASM; PATHOPHYSIOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION;

CYTOKINES; DISEASE PROGRESSION; DRUG DELIVERY SYSTEMS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; INFLAMMATION; NEOPLASM METASTASIS; NEOPLASMS; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; SIGNAL TRANSDUCTION;

EID: 77953117862     PISSN: 19450516     EISSN: 19450524     Source Type: Journal    
DOI: None     Document Type: Article

References (49)

1. Leland Chung: Molecular insights into prostate cancer progression: the missing link of tumor microenvironment. J Urol 173, 10-20 (2005) (Pubitemid 39627663)
2. Karin de Visser and Lisa Coussens: The inflammatory tumor microenvironment and its impact on cancer development. Contib Microbiol 13, 118-137 (2006)
3. Haitian Lu, Weiming Ouyang and Chuanshu Huang: Inflammation, a key event in cancer development. Mol Cancer Res 4, 221-233 (2004)
4. Joydeb Kumar Kundu and Young Joon Surh: Inflammation: gearing the journey to cancer. Mutat Res 659, 15-30 (2008)
5. Ben Baruch: Inflammation-associated immune suppression in cancer: the roles played by cytokines, chemokines, and additional mediators. Cancer Bio 16, 38-52 (2006)
6. Wan-Wan Lin: A cytokine-mediated link between innate immunity, inflammation, and cancer. J Clin Invest 117, 1175-1183 (2007) (Pubitemid 46718402)
7. Young Cho Chung and Yung Fu Chang: Serum interleukin-6 levels reflect the disease status of colorectal cancer. J Surg Oncol 83, 222-226 (2003)
8. Rik Derynck, Rosemary Akhurst and Allan Balmain: TGF-beta signalling in tumor suppression and cancer progression. Nat Genet 29, 117-129 (2001) (Pubitemid 32952643)
9. Raymond Dubois: Leukotriene A4 signalling, inflammation, and cancer. J Natl Cancer Inst 95, 1028-1029 (2003)
10. Fran Balkwill: Tumor necrosis factor or tumor promoting factor. Cytokine Growth Factor Rev 13, 135-141 (2002)
11. Maria Garcia-Hernandez, Rogelio Hernandez-Pando, Patricio Gariglio and Jaime Berumen: Interleukin-10 promotes B16-melanoma growth by inhibition of macrophage functions and induction of tumor and vascular cell proliferation. Immunology 105, 231-243 (2002) (Pubitemid 34146690)
12. Vernon Steele, Ernest Hawk, Jaye Viner and Ronald Lubet: Mechanisms and applications of non-steroidal anti-inflammatory drugs in the chemoprevention of cancer. Mutat Res 137, 523-524 (2003)
13. Masahiko Tsujii, Sunao Kawano and Raymond Dubois: Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential. Proc Natl Acad Sci USA 94, 3336-3340 (1997) (Pubitemid 27157312)
14. Katsunobu Oyama, Takashi Fujimura, Itasu Ninomiya, Tomoharu Miyashita, Shinichi Kinami, Sachio Fushida, Tetsuo Ohta and Miwa Koichi: A COX-2 inhibitor prevents the esophageal inflammation-metaplasia-adenocarcinoma sequence in rats. Carcinogenesis 26, 565-570 (2005) (Pubitemid 41214145)
15. Guang Wang, Bing-hua Jiang, Elizabeth Rue and Gregg Semenza: Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc Natl Acad Sci USA 92, 5510-5514 (1995)
16. Sarah Walmsley, Cristin Print and Neda Farahi: Hypoxia-induced neutrophil survival is mediated by HIF-1-dependent NF-kB activity. J Exp Med 201, 105-115 (2005) (Pubitemid 40130088)
17. Rakesh Jain: Tumor angiogenesis and accessibility; role of vascular endothelial growth factor. Semin Oncol 29, 3-9 (2002)
18. Jie Zhou, Tobias Schmid and Bernhard Brune: Tumor necrosis factor-alpha causes accumulation of a ubiuitinated form of hypoxia inducible factor-1 alpha through a nuclear factor kappa B pathway. Mol Bio Cell 14, 2216-2215 (2003)
19. Chinthalapally Rao: Nitric oxide signaling in colon cancer chemoprevention. Mutat Res 555, 107-119 (2004) (Pubitemid 39345400)
20. Meeta Jaiswal, Nicholas Larusso and Gregory Gores: Nitric oxide in gastrointestinal epithelial cell carcinogenesis; linking inflammation to oncogenesis. Am J Physiol Gastrointest Liver Physiol 281, 626-634 (2001)
21. Meeta Jaiswal, Nicholas Larusso, Lawrence Burgart and Gregory Gores: Inflammatory cytokines induce DNA damage and inhibit DNA repair in cholangiocarcinoma cells by a nitric oxide-dependent mechanism. Cancer Res 60, 184-190 (2000) (Pubitemid 30058750)
22. Qiutang Li and Inder Verma: NF-kB regulation in the immune system. Nat Rev Immunol 2, 725-734 (2002)
23. Isaac Witz: Presence and functions of immune components in the tumor microenvironment. Adv Exp Med Biol 495, 317-324 (2001) (Pubitemid 34106953)
24. Russell Leek and Adrian Harris: Tumor-associated macrophages in breast cancer. J Mammary Gland Biol Neoplasia 7, 229-235 (2002)
25. Cliona O'Sullivan and Claire Lewis: Tumour-associated leucocytes: friends or foes in breast carcinoma. J Pathol 172, 147-162.
26. Jeffrey Pollard: Tumour-educated macrophages promote tumour progression and metastasis. Nat Rev Cancer 4, 71-78 (2004) (Pubitemid 38082155)
27. Edgardo Ariztia, Catherine Lee, Radhika Gogoi and David Fishman: The tumor microenvironment: key to early detection. Crit Rev Clin Lab Sci 43, 393-425 (2006) (Pubitemid 44596061)
28. Thea Tlsty and Lisa Coussens: Tumor stroma and regulation of cancer development. Annu Rev Pathol 1, 119-150 (2006)
29. Joyce Tse and Raghu Kalluri: Mechanisms of metastasis: epithelial-to-mesenchymal transition and contribution of tumor microenvironment. J Cell Biochem 101, 816-829 (2007) (Pubitemid 47040864)
30. Siamon Gordon and Philip Taylor: Monocyte and macrophages heterogeneity. Nat Rev Immunol 5, 953-964 (2005)
31. Lynne Bingle, Claire Lewis, Kevin Corke, Mike Reed and Nancy Brown: Macrophages promote angiogenesis in human breast tumor spheroids in vivo. Br J Cancer 94, 101-107 (2006) (Pubitemid 43088548)
32. Paola Allavena, Antonio Sica, Graziella Solinas, Chiara Porta and Alberto Mantovani: The inflammatory microenvironment in tumor progression: the role of tumor associated macrophages. Crit Rev Oncol/Hematol 66, 1-9 (2008) (Pubitemid 351324128)
33. Fran Balkwill and Alberto Mantovani: Inflammation and cancer: back to Virchow. Lancet 357, 539-545 (2001)
34. Steven Itzkowitz and Xianyang Yio: Inflammation and cancer. IV. colorectal cancer in inflammatory bowel disease: the role of inflammation. Am J Physiol Gastrointest Liver Physiol 287, 7-17 (2004)
35. George Moody, Venkataraman Jayanthi, Chris Probert, Helen MacKay and John Mayberry: Long term therapy with sulphasalzine protects against colorectal cancer in ulcerative colitis; a retrospective study of colorectal cancer risk and compliance with treatment in Leicestershire. Eur J Gastroenterol Hepatol 8, 1179-1183 (1996) (Pubitemid 26413548)
36. Jayne Eaden, Keith Abrams, Andreas Ekborn and John Mayberry: Colorectal cancer prevention in ulcerstive colitis: a case control study. Aliment Pharmacol Ther 14, 145-153 (2000) (Pubitemid 30088290)
37. Laura Alba, Paul Angulo and Keith Lindor: Primary sclerosing cholangitis. Minerva Gastroenterol Dietol 48, 99-113 (2002) (Pubitemid 34790720)
38. Jessica Haverkamp, Bridget Charbonneau and Timothy Ratliff: Prostate inflammation and its potential impact on prostate cancer: a current review. J Cell Biochem 103, 1344-1353 (2007)
39. Timothy Block, Anand Mehta, Claus Fimmel and Robert Jordan: Molecular viral oncology of hepatocellular carcinoma. Oncogene 22, 5093-5107 (2003) (Pubitemid 37059591)
40. Paola Allavena, Cecilia Garlanda, Maria Grazia Borrello and Antonio Sica: Pathways connecting inflammation and cancer. Curr Opin Genet & Dev 18, 3-10 (2008) (Pubitemid 351694444)
41. David Hodge, Elaine Hurt and William Farrar: The role of IL-6 and STAT3 in inflammation and cancer. Eur J Cancer 41, 2502-2512 (2005) (Pubitemid 41540626)
42. Jinbo Yang, Moitreyee Chatterjee-Kishore and Susan Staugaitis: Novel roles of unphosphorylated STAT3 in oncogenesis and transcriptional regulation. Cancer Res 65, 939-947 (2005) (Pubitemid 40216455)
43. Javier Duque, Manuel Frresno and Miguel Iniguez: Expression and function of the nuclear factor of activated T cells in colon carcinoma cells. J Biol Chem 289, 8686-8693 (2005)
44. Ingrid Joseph and John Isaacs: Macrophage role in the antiprostate cancer response to one class of antiangiogenic agents. J Natl Cancer Inst 90, 1648-1653 (1998) (Pubitemid 28523439)
45. Alan Sandler, Robert Gray and Michael Perry: Paclitaxel-carboplatin alone or with combination with bevacizumab for non-small cell lung carcinoma. N England J Med 355, 2542-2550 (2006) (Pubitemid 44917502)
46. Eli Pikarsky: NF-kB functions as a tumor promoter in inflammation- associated cancer. Nature 431, 461-466 (2004) (Pubitemid 39329586)
47. Florian Greten: IKKB links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell 118, 285-296 (2004) (Pubitemid 39061110)
48. Frank Fitzpatrick: Inflammation, carcinogenesis and cancer. Int Immunopharmacol 1, 1651-1667 (2001) (Pubitemid 32772637)
49. Lisa Coussens and Zena Werb: Inflammation and cancer. Nature 420, 860-867 (2002) (Pubitemid 36019639)