-
1
-
-
33745303045
-
Hypoxia signaling in cancer and approaches to enforce tumor regression
-
Pouyssegur J, Dayan F and Mazure NM: Hypoxia signaling in cancer and approaches to enforce tumor regression. Nature 441: 437-443, 2006.
-
(2006)
Nature
, vol.441
, pp. 437-443
-
-
Pouyssegur, J.1
Dayan, F.2
Mazure, N.M.3
-
2
-
-
24944510719
-
Hypoxia activates the cyclin D1 promoter via the Jak2/STAT5b pathway in breast cancer cells
-
Joung YH, Lim EJ, Lee MY, Park JH, Ye SK, Park EU, Kim SY, Zhang Z, Lee KJ, Park DK, Park TK, Moon WK and Yang YM: Hypoxia activates the cyclin D1 promoter via the Jak2/STAT5b pathway in breast cancer cells. Exp Mol Med 37: 353-364, 2005.
-
(2005)
Exp Mol Med
, vol.37
, pp. 353-364
-
-
Joung, Y.H.1
Lim, E.J.2
Lee, M.Y.3
Park, J.H.4
Ye, S.K.5
Park, E.U.6
Kim, S.Y.7
Zhang, Z.8
Lee, K.J.9
Park, D.K.10
Park, T.K.11
Moon, W.K.12
Yang, Y.M.13
-
3
-
-
0031918244
-
Regulation of proliferation-survival decisions during tumor cell hypoxia
-
Schmaltz C, Hardenbergh PH, Wells A and Fisher DE: Regulation of proliferation-survival decisions during tumor cell hypoxia. Mol Cell Biol 18: 2845-2854, 1998.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 2845-2854
-
-
Schmaltz, C.1
Hardenbergh, P.H.2
Wells, A.3
Fisher, D.E.4
-
4
-
-
0030025773
-
Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours
-
Graeber TG, Osmanian C, Jacks T, Housman DE, Koch CJ, Lowe SW and Giaccia AJ: Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours. Nature 379: 88-91, 1996.
-
(1996)
Nature
, vol.379
, pp. 88-91
-
-
Graeber, T.G.1
Osmanian, C.2
Jacks, T.3
Housman, D.E.4
Koch, C.J.5
Lowe, S.W.6
Giaccia, A.J.7
-
5
-
-
0034743861
-
Oxygen status of malignant tumors: Pathogenesis of hypoxia and significance for tumor therapy
-
Vaupel P, Kelleher DK and Hockel M: Oxygen status of malignant tumors: pathogenesis of hypoxia and significance for tumor therapy. Semin Oncol 28: 29-35, 2001.
-
(2001)
Semin Oncol
, vol.28
, pp. 29-35
-
-
Vaupel, P.1
Kelleher, D.K.2
Hockel, M.3
-
6
-
-
0022450587
-
Regulation of protein metabolism of human cells during and after acute hypoxia
-
Pettersen EO, Juul NO and Ronning OW: Regulation of protein metabolism of human cells during and after acute hypoxia. Cancer Res 46: 4346-4351, 1986.
-
(1986)
Cancer Res
, vol.46
, pp. 4346-4351
-
-
Pettersen, E.O.1
Juul, N.O.2
Ronning, O.W.3
-
7
-
-
0032407157
-
Hypoxia-mediated regulation of gene expression in mammalian cells
-
Shih SC and Claffey KP: Hypoxia-mediated regulation of gene expression in mammalian cells. Int J Exp Pathol 79: 347-357, 1998.
-
(1998)
Int J Exp Pathol
, vol.79
, pp. 347-357
-
-
Shih, S.C.1
Claffey, K.P.2
-
8
-
-
0344873719
-
Hypoxia activates signal transducers and activators of transcription 5 (STAT5) and increases its binding activity to the GAS element in mammary epithelial cells
-
Joung YH, Park JH, Park TK, Lee CS, Kim OH, Ye SK, Yang UM, Lee KJ and Yang YM: Hypoxia activates signal transducers and activators of transcription 5 (STAT5) and increases its binding activity to the GAS element in mammary epithelial cells. Exp Mol Med 35: 350-357, 2003.
-
(2003)
Exp Mol Med
, vol.35
, pp. 350-357
-
-
Joung, Y.H.1
Park, J.H.2
Park, T.K.3
Lee, C.S.4
Kim, O.H.5
Ye, S.K.6
Yang, U.M.7
Lee, K.J.8
Yang, Y.M.9
-
9
-
-
34249295949
-
Hypoxia activates the IGF-1 expression through STAT5b in human HepG2 cells
-
Joung YH, Lee MY, Lim EJ, Kim MS, Hwang TS, Kim SY, Kim SY, Ye SK, Lee JD, Park TK, Woo YS, Chung IM and Yang YM: Hypoxia activates the IGF-1 expression through STAT5b in human HepG2 cells. Biochem Biophys Res Commun 358: 733-738, 2007.
-
(2007)
Biochem Biophys Res Commun
, vol.358
, pp. 733-738
-
-
Joung, Y.H.1
Lee, M.Y.2
Lim, E.J.3
Kim, M.S.4
Hwang, T.S.5
Kim, S.Y.6
Kim, S.Y.7
Ye, S.K.8
Lee, J.D.9
Park, T.K.10
Woo, Y.S.11
Chung, I.M.12
Yang, Y.M.13
-
10
-
-
33646527342
-
Phosphorylation and activation of STAT proteins by hypoxia in breast cancer cells
-
Lee MY, Joung YH, Lim EJ, Park JH, Ye SK, Park TK, Zhang Z, Park DK, Lee KJ and Yang YM: Phosphorylation and activation of STAT proteins by hypoxia in breast cancer cells. Breast 15: 187-195, 2006.
-
(2006)
Breast
, vol.15
, pp. 187-195
-
-
Lee, M.Y.1
Joung, Y.H.2
Lim, E.J.3
Park, J.H.4
Ye, S.K.5
Park, T.K.6
Zhang, Z.7
Park, D.K.8
Lee, K.J.9
Yang, Y.M.10
-
11
-
-
0030788405
-
Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis
-
Chin YE, Kitagawa M, Kuida K, Flavell RA and Fu XY: Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis. Mol Cell Biol 17: 5328-5337, 1997.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 5328-5337
-
-
Chin, Y.E.1
Kitagawa, M.2
Kuida, K.3
Flavell, R.A.4
Fu, X.Y.5
-
12
-
-
25144496007
-
A VEGF/JAK2/STAT5 axis may partially mediate endothelial cell tolerance to hypoxia
-
Dudley AC, Thomas D, Best J and Jenkins A: A VEGF/JAK2/STAT5 axis may partially mediate endothelial cell tolerance to hypoxia. Biochem J 390: 427-436, 2005.
-
(2005)
Biochem J
, vol.390
, pp. 427-436
-
-
Dudley, A.C.1
Thomas, D.2
Best, J.3
Jenkins, A.4
-
13
-
-
4544369601
-
Dominant-negative Stat5 inhibits growth and induces apoptosis in T47D-derived tumors in nude mice
-
Yamashita H, Nishio M, Fujii Y and Iwase H: Dominant-negative Stat5 inhibits growth and induces apoptosis in T47D-derived tumors in nude mice. Cancer Sci 95: 662-665, 2004.
-
(2004)
Cancer Sci
, vol.95
, pp. 662-665
-
-
Yamashita, H.1
Nishio, M.2
Fujii, Y.3
Iwase, H.4
-
14
-
-
0032906921
-
Apoptosis and cell-cycle arrest in human and murine tumor cells are initiated by isoprenoids
-
Mo H and Elson CE: Apoptosis and cell-cycle arrest in human and murine tumor cells are initiated by isoprenoids. J Nutr 129: 804-813, 1999.
-
(1999)
J Nutr
, vol.129
, pp. 804-813
-
-
Mo, H.1
Elson, C.E.2
-
15
-
-
0037249834
-
CSE1L/CAS: Its role in proliferation and apoptosis
-
Behrens P, Brinkmann U and Wellmann A: CSE1L/CAS: its role in proliferation and apoptosis. Apoptosis 8: 39-44, 2003.
-
(2003)
Apoptosis
, vol.8
, pp. 39-44
-
-
Behrens, P.1
Brinkmann, U.2
Wellmann, A.3
-
16
-
-
33845973448
-
Cranberry phytochemical extracts induce cell cycle arrest and apoptosis in human MCF-7 breast cancer cells
-
Sun J and Liu RH: Cranberry phytochemical extracts induce cell cycle arrest and apoptosis in human MCF-7 breast cancer cells. Cancer Lett 241: 124-134, 2006.
-
(2006)
Cancer Lett
, vol.241
, pp. 124-134
-
-
Sun, J.1
Liu, R.H.2
-
17
-
-
33947577698
-
Cytotoxic and antitumor activity of Momilactone B from rice hulls
-
Kim SJ, Park HR, Park EJ and Lee SC: Cytotoxic and antitumor activity of Momilactone B from rice hulls. J Agric Food Chem 55: 1702-1706, 2007.
-
(2007)
J Agric Food Chem
, vol.55
, pp. 1702-1706
-
-
Kim, S.J.1
Park, H.R.2
Park, E.J.3
Lee, S.C.4
-
18
-
-
0035961952
-
Cytotoxicity effects of di- and tri-hydroxybenzaldehydes as a chemopreventive potential agent on tumor cells
-
Tseng TH, Tsheng YM and Lee YJ: Cytotoxicity effects of di- and tri-hydroxybenzaldehydes as a chemopreventive potential agent on tumor cells. Toxicology 161: 179-187, 2001.
-
(2001)
Toxicology
, vol.161
, pp. 179-187
-
-
Tseng, T.H.1
Tsheng, Y.M.2
Lee, Y.J.3
-
19
-
-
0037872699
-
Angiogenesis in ischemic and neoplastic disorders
-
Semenza GL: Angiogenesis in ischemic and neoplastic disorders. Annu Rev Med 54: 17-28, 2003.
-
(2003)
Annu Rev Med
, vol.54
, pp. 17-28
-
-
Semenza, G.L.1
-
20
-
-
0035191993
-
Natural antioxidants from residual sources
-
More A, Cruz JM, Franco D, Domiguez JM, Sineiro J, Dominguez H, Nunez MJ and Parajo JC: Natural antioxidants from residual sources. Food Chem 72: 145-171, 2001.
-
(2001)
Food Chem
, vol.72
, pp. 145-171
-
-
More, A.1
Cruz, J.M.2
Franco, D.3
Domiguez, J.M.4
Sineiro, J.5
Dominguez, H.6
Nunez, M.J.7
Parajo, J.C.8
-
21
-
-
0037425490
-
Silicate thermal insulation material from rice hull ash
-
Kalapathy U, Proctor A and Shultz J: Silicate thermal insulation material from rice hull ash. Ind Eng Chem Res 42: 46-49, 2003.
-
(2003)
Ind Eng Chem Res
, vol.42
, pp. 46-49
-
-
Kalapathy, U.1
Proctor, A.2
Shultz, J.3
-
22
-
-
0038002985
-
Rice seedling release momilactone B into the environment
-
Hisashi KN and Takeshi I: Rice seedling release momilactone B into the environment. Phytochemistry 63: 551-554, 2003.
-
(2003)
Phytochemistry
, vol.63
, pp. 551-554
-
-
Hisashi, K.N.1
Takeshi, I.2
-
23
-
-
33646007931
-
Evaluation of allelopathic potential and quantification of Momilactone A,B from rice hull extracts and assessment of inhibitory bioactivity on paddy field weeds
-
Chung IM, Kim JT and Kim SH: Evaluation of allelopathic potential and quantification of Momilactone A,B from rice hull extracts and assessment of inhibitory bioactivity on paddy field weeds. J Agric Food Chem 54: 2527-2536, 2006.
-
(2006)
J Agric Food Chem
, vol.54
, pp. 2527-2536
-
-
Chung, I.M.1
Kim, J.T.2
Kim, S.H.3
-
24
-
-
0036251154
-
Stat proteins and oncogenesis
-
Bromberg J: Stat proteins and oncogenesis. J Clin Invest 109: 1139-1142, 2002.
-
(2002)
J Clin Invest
, vol.109
, pp. 1139-1142
-
-
Bromberg, J.1
-
25
-
-
0036625960
-
The role of STATs in apoptosis
-
Battle TE and Frank DA: The role of STATs in apoptosis. Curr Mol Med 2: 381-392, 2002.
-
(2002)
Curr Mol Med
, vol.2
, pp. 381-392
-
-
Battle, T.E.1
Frank, D.A.2
-
26
-
-
0036554816
-
Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention
-
Buettner R, Mora LB and Jove R: Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention. Clin Cancer Res 8: 945-954, 2002.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 945-954
-
-
Buettner, R.1
Mora, L.B.2
Jove, R.3
-
27
-
-
0033564697
-
CDK inhibitors: Positive and negative regulators of G1-phase progression
-
Sherr CJ and Roberts JM: CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev 13: 1501-1512, 1999.
-
(1999)
Genes Dev
, vol.13
, pp. 1501-1512
-
-
Sherr, C.J.1
Roberts, J.M.2
-
28
-
-
2442675495
-
Blocking of FGFR signaling inhibits breast cancer cell proliferation through downregulation of D-type cyclins
-
Koziczak M, Holbro T and Hynes NE: Blocking of FGFR signaling inhibits breast cancer cell proliferation through downregulation of D-type cyclins. Oncogene 23: 3501-3508, 2004.
-
(2004)
Oncogene
, vol.23
, pp. 3501-3508
-
-
Koziczak, M.1
Holbro, T.2
Hynes, N.E.3
-
29
-
-
0035714568
-
Contribution of bcl-2, but not bcl-xL and bax, to antiapoptotic actions of hepatocyte growth factor in hypoxia-conditioned human endothetial cells
-
Yamamoto K, Morishita R, Hayashi S, Matsushita H, Nakagami H, Moriguchi A, Matsumoto K, Nakmura T, Kaneda Y and Ogihara T: Contribution of bcl-2, but not bcl-xL and bax, to antiapoptotic actions of hepatocyte growth factor in hypoxia-conditioned human endothetial cells. Hypertension 37: 1341-1348, 2001.
-
(2001)
Hypertension
, vol.37
, pp. 1341-1348
-
-
Yamamoto, K.1
Morishita, R.2
Hayashi, S.3
Matsushita, H.4
Nakagami, H.5
Moriguchi, A.6
Matsumoto, K.7
Nakmura, T.8
Kaneda, Y.9
Ogihara, T.10
-
31
-
-
0028912505
-
Induction of apoptosis at different oxygen tensions: Evidence that oxygen radicals do not mediate apoptotic signaling
-
Muschel RJ., Bernhard EJ, Garza L, McKenna WG and Koch CJ: Induction of apoptosis at different oxygen tensions: evidence that oxygen radicals do not mediate apoptotic signaling. Cancer Res 55: 995-998, 1995.
-
(1995)
Cancer Res
, vol.55
, pp. 995-998
-
-
Muschel, R.J.1
Bernhard, E.J.2
Garza, L.3
McKenna, W.G.4
Koch, C.J.5
-
32
-
-
0032575750
-
Caspases: Enemies within
-
Thornberry N and Lazebnik Y: Caspases: enemies within. Science 281: 1312-1316, 1998.
-
(1998)
Science
, vol.281
, pp. 1312-1316
-
-
Thornberry, N.1
Lazebnik, Y.2
-
33
-
-
33644830768
-
The p53-dependent apoptotic pathway of breast cancer cells (BC-M1) induced by the bis-type bioreductive compound aziridinyl-naphthoquinone
-
Yang YP, Kuo HS, Tsai HD, Peng YC and Lin YL: The p53-dependent apoptotic pathway of breast cancer cells (BC-M1) induced by the bis-type bioreductive compound aziridinyl-naphthoquinone. Breast Cancer Res 7: R19-R27, 2005.
-
(2005)
Breast Cancer Res
, vol.7
-
-
Yang, Y.P.1
Kuo, H.S.2
Tsai, H.D.3
Peng, Y.C.4
Lin, Y.L.5
-
34
-
-
0035793923
-
Cyclin A/cdk2 activation is involved in hypoxia-induced apoptosis in cardiomyocytes
-
Adachi S, Ito H, Tamamori-Adachi M, Ono Y, Nozato T, Abe S, Ikeda MA, Marumo F and Hiroe M: Cyclin A/cdk2 activation is involved in hypoxia-induced apoptosis in cardiomyocytes. Circ Res 88: 408-414, 2001.
-
(2001)
Circ Res
, vol.88
, pp. 408-414
-
-
Adachi, S.1
Ito, H.2
Tamamori-Adachi, M.3
Ono, Y.4
Nozato, T.5
Abe, S.6
Ikeda, M.A.7
Marumo, F.8
Hiroe, M.9
-
35
-
-
33745827711
-
Molecular iodine induces caspase-independent apoptosis in human breast carcinoma cells involving mitochondria-mediated pathway
-
Shrivastava A, Tiwari M, Sinha RA, Kumar A, Balapure AK., Bajpai VK, Sharma R, Mitra K, Tandon A and Godbole MM: Molecular iodine induces caspase-independent apoptosis in human breast carcinoma cells involving mitochondria-mediated pathway. J Biol Chem 281: 19762-19771, 2006.
-
(2006)
J Biol Chem
, vol.281
, pp. 19762-19771
-
-
Shrivastava, A.1
Tiwari, M.2
Sinha, R.A.3
Kumar, A.4
Balapure, A.K.5
Bajpai, V.K.6
Sharma, R.7
Mitra, K.8
Tandon, A.9
Godbole, M.M.10
-
37
-
-
0027166048
-
Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
-
Oltvai ZN, Milliman S and Korsmeyer SJ: Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74: 609-619, 1993.
-
(1993)
Cell
, vol.74
, pp. 609-619
-
-
Oltvai, Z.N.1
Milliman, S.2
Korsmeyer, S.J.3
-
38
-
-
0035853811
-
Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells
-
Antonsson B, Montessuit S, Sanchez B and Martinou JC: Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells. J Biol Chem 276: 11615-11623, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 11615-11623
-
-
Antonsson, B.1
Montessuit, S.2
Sanchez, B.3
Martinou, J.C.4
-
39
-
-
18844480398
-
Thrombopoietin-induced differentiation of a human megakaryoblastic leukemia cell line, CMK, involves transcriptional activation of p21 (WAF1/Cip1) by STAT5
-
Matsumura I, Ishikawa J, Nakajima K, Oritani K, Tomiyama Y, Miyagawa J, Kato T, Miyazaki H, Matsuzawa Y and Kanakura Y: Thrombopoietin-induced differentiation of a human megakaryoblastic leukemia cell line, CMK, involves transcriptional activation of p21 (WAF1/Cip1) by STAT5. Mol Cell Biol 17: 2933-2943, 1997.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 2933-2943
-
-
Matsumura, I.1
Ishikawa, J.2
Nakajima, K.3
Oritani, K.4
Tomiyama, Y.5
Miyagawa, J.6
Kato, T.7
Miyazaki, H.8
Matsuzawa, Y.9
Kanakura, Y.10
|