Regulation of HERG (KCNH2) potassium channel surface expression by diacylglycerol

Cellular and Molecular Life Sciences

Volumn 67, Issue 1, 2010, Pages 157-169

  Ramström, Cia ^a,b   Chapman, Hugh ^b   Viitanen, Tero ^b   Afrasiabi, Emad ^a   Fox, Heli ^b   Kivelä, Johanna ^c   Soini, Sanna ^c   Korhonen, Laura ^b   Lindholm, Dan ^b   Pasternack, Michael ^b   Törnquist, Kid ^a  

^a ÅBO AKADEMI UNIVERSITY   (Finland)

^b MINERVA FOUNDATION INSTITUTE FOR MEDICAL RESEARCH   (Finland)

^c UNIVERSITY OF TURKU   (Finland)

Author keywords

Diacylglycerol; Internalization; Lipids; Lysosomes; Membranes; Potassium channel; Protein kinase C

Indexed keywords

DIACYLGLYCEROL; DYNAMIN; DYNEIN ADENOSINE TRIPHOSPHATASE; POTASSIUM CHANNEL HERG; PROTEIN KINASE C;

ARTICLE; CELL SURFACE; COMPLEX FORMATION; CONTROLLED STUDY; EMBRYO CELL; ENDOCYTOSIS; ENDOSOME; EVOKED RESPONSE; HUMAN; HUMAN CELL; KIDNEY CELL; LYSOSOME; POTASSIUM CURRENT; POTASSIUM TRANSPORT; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STABILITY; REGULATORY MECHANISM;

CELL LINE; DIGLYCERIDES; DYNAMINS; DYNEINS; ELECTROPHYSIOLOGICAL PHENOMENA; ENDOCYTOSIS; ENDOSOMES; ETHER-A-GO-GO POTASSIUM CHANNELS; HUMANS; IMMUNOPRECIPITATION; PROTEIN KINASE C;

EID: 73749086374     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-009-0176-2     Document Type: Article

References (52)

1. IB Levitan 1994 Modulation of ion channels by protein phosphorylation and dephosphorylation Annu Rev Physiol 56 737 745 10.1146/annurev.ph.56.030194. 001205
2. JW Warmke B Ganetzky 1994 A family of potassium channel genes related to eag in Drosophila and mammals Proc Natl Acad Sci USA 91 3438 3442 10.1073/pnas.91.8.3438 1:CAS:528:DyaK2cXksFWjt74%3D 8159766
3. MC Sanguinetti C Jiang ME Curran MT Keating 1995 A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel Cell 81 299 307 10.1016/0092-8674(95)90340-2 1:CAS:528:DyaK2MXlt1Kis7w%3D 7736582
4. ME Curran I Splawski KW Timothy GM Vincent ED Green MT Keating 1995 A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome Cell 80 795 803 10.1016/0092-8674(95)90358-5 1:CAS:528:DyaK2MXksVahsL4%3D 7889573
5. R Brugada K Hong R Dumaine J Cordeiro F Gaita M Borggrefe TM Menendez J Brugada GD Pollevick C Wolpert E Burashnikov K Matsuo A Guerchicoff F Bianchi C Guistetto R Schimpf P Brugada 2004 Sudden death associated with short-QT syndrome linked to mutations in HERG Circulation 109 30 35 10.1161/01.CIR. 0000109482.92774.3A 1:CAS:528:DC%2BD3sXhtVWjtrnK 14676148 (Pubitemid 38056017)
6. YG Yap AJ Camm 2003 Drug induced QT prolongation and torsades de pointes Heart 89 1363 1372 10.1136/heart.89.11.1363 1:CAS:528:DC%2BD3sXptleit78%3D 14594906
7. N Chiesa B Rosati A Arcangeli M Olivotto E Wanke 1997 A novel role for HERG K+ channels: spike-frequency adaptation J Physiol 501 313 318 10.1111/j.1469-7793.1997.313bn.x 1:CAS:528:DyaK2sXkt1eqtrY%3D 9192303 (Pubitemid 27280806)
8. AM Farrelly S Ros BP Callaghan MA Khoyi N Flemming B Horowitz KM Sanders KD Keef 3003 Expression and function of KCNH2 (HERG) in the human jejunum Am J Physiol Gastrointest Liver Physiol 284 G883 G895
9. B Rosati P Marchetti O Crociani M Lecchi RA Lupi A Arcangeli M Olivotto E Wanke 2000 Glucose- and arginine-induced insulin secretion by human pancreatic beta-cells: the role of HERG K(+) channels in firing and release FASEB J. 14 2601 2610 10.1096/fj.00-0077com 1:CAS:528:DC%2BD3MXht1Sntbw%3D 11099479
10. E Lastraioli L Guasti O Crociani S Polvani G Hofmann H Witchel L Bencini M Calistri L Messerini M Scatizzi PA Moretti E Wanke M Olivotto G Mugnai A Arcangeli 2004 herg1 gene and HERG1 protein are overexpressed in colorectal cancers and regulate cell invasion of tumor cells Cancer Res 64 606 611 10.1158/0008-5472.CAN-03-2360 1:CAS:528:DC%2BD2cXmsVajug%3D%3D 14744775 (Pubitemid 38120900)
11. H Wang Y Zhang L Cao H Han J Wang B Yang S Nattel Z Wang 2002 HERG K+ channel, a regulator of tumor cell apoptosis and proliferation Cancer Res 62 4843 4848 1:CAS:528:DC%2BD38XmslyltbY%3D 12208728
12. FJ Johannes J Prestle S Dieterich P Oberhagemann G Link K Pfizenmaier 1995 Characterization of activators and inhibitors of protein kinase C mu Eur J Biochem 15 303 307 10.1111/j.1432-1033.1995.tb20389.x
13. B Canagarajah FC Leskow JY Ho H Mischak LF Saidi MG Kazanietz JH Hurley 2004 Structural mechanism for lipid activation of the Rac-specific GAP, beta2-chimaerin Cell 119 407 418 10.1016/j.cell.2004.10.012 1:CAS:528: DC%2BD2cXpvFOgtbk%3D 15507211 (Pubitemid 39423842)
14. B Attali E Honoré F Lesage M Lazdunski J Bathain 1992 Regulation of a major cloned voltage-gated K+ channel from human T lymphocytes FEBS Lett 303 229 232 10.1016/0014-5793(92)80526-M 1:CAS:528:DyaK38XksVKmsLw%3D 1607023
15. CF Lo R Numann 1998 Independent and exclusive modulation of cardiac delayed rectifying K+ current by protein kinase C and protein kinase A Circ Res 83 995 1002 1:CAS:528:DyaK1cXnsVykurs%3D 9815147
16. J Bian J Cui TV McDonald 2001 HERG K(+) channel activity is regulated by changes in phosphatidyl inositol 4, 5-bisphosphate Circ Res 89 1168 1176 10.1161/hh2401.101375 1:CAS:528:DC%2BD3MXptFKmtL0%3D 11739282
17. 3 lactotrophes Endocrinology 142 4785 4794 10.1210/en.142.11.4785 1:CAS:528:DC%2BD3MXnslGqtbc%3D 11606445 (Pubitemid 33022354)
18. + channel by ceramide: Evidence for ubiquitin-mediated lysosomal degradation J Cell Sci 118 5325 5334 10.1242/jcs.02635 1:CAS:528: DC%2BD2MXhtlWru7vP 16263765 (Pubitemid 41819594)
19. D Thomas W Zhang K Wu AB Wimmer B Gut G Wendt-Nordahl S Kathöfer VA Kreye HA Kathus W Schoels J Kiehn CA Karle 2003 Regulation of HERG potassium channel activation by protein kinase C independent of direct phosphorylation of the channel protein Cardiovasc Res 59 14 26 10.1016/S0008-6363(03)00386-9 1:CAS:528:DC%2BD3sXkvVKisLw%3D 12829172 (Pubitemid 36776369)
20. F Barros D Gomez-Varela CG Vitoria T Giraldéz P de la Pena 1998 Modulation of human erg K+ channel gating by activation of a G protein-coupled receptor and protein kinase C J Physiol 511 333 346 10.1111/j.1469-7793.1998. 333bh.x 1:CAS:528:DyaK1cXmsFOnsLs%3D 9706014 (Pubitemid 28444606)
21. SL Cockerill AB Tobin I Torrecilla GB Willars NB Standen JS Mitcheson 2007 Modulation of hERG potassium currents in HEK-293 cells by protein kinase C. Evidence for direct phosphorylation f pore forming subunits J Physiol 581 479 493 10.1113/jphysiol.2006.123414 1:STN:280:DC%2BD2szivFKhuw%3D%3D 17363390 (Pubitemid 46831751)
22. AFB Arcangeli A Becchetti L Faravelli M Coronello E Mini M Olivotto E Wanke 1995 A novel inward-rectifying K+ current with a cell-cycle dependence governs the resting potential of mammalian neuroblastoma cells J Physiol 489 455 471 1:CAS:528:DyaK28XitFOlsw%3D%3D 8847640
23. Z Zhou Q Gong B Ye Z Fan JC Makielski GA Robertson CT January 1998 Properties of HERG channels stably expressed in HEK 293 cells studied at physiological temperature Biophys J 74 230 241 10.1016/S0006-3495(98)77782-3 1:CAS:528:DyaK1cXhvFWjurg%3D 9449325
24. GEN Kass SK Duddy S Orrenius 1989 Activation of hepatocyte protein kinase C by redox-cycling quinones Biochem J 260 499 507 1:CAS:528:DyaL1MXkvFaksr4%3D 2764885
25. Y Nong YO Huang W Ju LV Kalia G Ahmadian YT Wang MW Salter 2003 Glycine binding primes NMDA receptor internalization Nature 422 302 307 10.1038/nature01497 1:CAS:528:DC%2BD3sXitFKmu7g%3D 12646920 (Pubitemid 36378356)
26. O Crociani L Guasti M Balzi A Becchetti E Wanke M Olivotto RS Wymore A Arcangeli 2003 Cell cycle-dependent expression of HERG1 and HERG1B isoforms in tumor cells J Biol Chem 278 2947 2955 10.1074/jbc.M210789200 1:CAS:528:DC%2BD3sXmt1Gmtw%3D%3D 12431979 (Pubitemid 36801200)
27. M Liscovitch 1992 Crosstalk among multiple signal-activated phospholipases Trends Biochem Sci 17 393 399 10.1016/0968-0004(92)90007-V 1:CAS:528:DyaK38XmtlSksr4%3D 1455508
28. Y Asaoka S Nakamura K Yoshida Y Nishizuka 1992 Protein kinase C, calcium and phospholipid degradation Trends Biochem Sci 17 414 417 10.1016/0968-0004(92) 90011-W 1:CAS:528:DyaK38XmtlSksro%3D 1455509
29. 1 receptor Br J Pharmacol 154 429 439 10.1038/bjp.2008.95 1:CAS:528:DC%2BD1cXlvVWnsrg%3D 18414380 (Pubitemid 351670608)
30. W Schledermann I Wulfsen JR Schwrz CK Bauer 2001 Modulation of rat erg1, erg2, erg3 and HERG K+ currents by thyrotropin-releasing hormone in anterior pituitary cells via the native signal cascade J Physiol 532 143 163 10.1111/j.1469-7793.2001.0143g.x 1:CAS:528:DC%2BD3MXjs1Oqsb4%3D 11283231 (Pubitemid 32303278)
31. D Gomez-Varela T Giraldéz P de la Pena SG Dupuy D Garcia-Manso F Barros 2003 Protein kinase C is necessary for recovery from the thyrotropin-releasing hormone-induced r-ERG current reduction in GH3 rat anterior pituitary cells J Physiol 547 913 929 10.1113/jphysiol.2002.034611 1:CAS:528:DC%2BD3sXjt1Slt70%3D 12562894 (Pubitemid 36367372)
32. P Delmas DA Brown 2005 Pathways modulating neural KCNQ/M (Kv7) potassium currents Nat Rev Neurosci 6 850 862 10.1038/nrn1785 1:CAS:528:DC%2BD2MXhtFKls7nE 16261179 (Pubitemid 41568727)
33. BM Heath DA Terrar 2000 Protein kinase C enhances the rapidly activating delayed rectifier potassium current, IKr, through a reduction in C-type inactivation in guinea-pig ventricular myocytes J Physiol 522 391 402 10.1111/j.1469-7793.2000.t01-2-00391.x 1:CAS:528:DC%2BD3cXhslaiu78%3D 10713964
34. JL Leaney LV Dekker A Tinker 2001 Regulation of a G protein-gated inwardly rectifying K+ channel by a Ca(2+)-independent protein kinase C J Physiol 534 367 379 10.1111/j.1469-7793.2001.00367.x 1:CAS:528: DC%2BD3MXlvVSku7g%3D 11454957 (Pubitemid 32677734)
35. PR Perillan M Chen EA Potts JM Simard 2002 Transforming growth factor-beta 1 regulates Kir2.3 inward rectifier K+ channels via phospholipase C and protein kinase C-delta in reactive astrocytes from adult rat brain J Biol Chem 277 1974 1980 10.1074/jbc.M107984200 1:CAS:528:DC%2BD38XosFensQ%3D%3D 11713246 (Pubitemid 34968777)
36. CA Karle E Zitron W Zhang G Wendt-Nordahl S Kathöfer D Thomas B Gut E Scholz CF Vahl HA Katus J Kiehn 2002 Human cardiac inwardly-rectifying K+ channel Kir(2.1b) is inhibited by direct protein kinase C-dependent regulation in human isolated cardiomyocytes and in an expression system Circulation 106 1493 1499 10.1161/01.CIR.0000029747.53262.5C 1:CAS:528:DC%2BD38XntVKksbs%3D 12234954 (Pubitemid 35050876)
37. J Mao X Wang F Chen R Wang A Rojas Y Shi H Piao C Jiang 2004 Molecular basis for the inhibition of G protein-coupled inward rectifier K(+) channels by protein kinase C Proc Natl Acad Sci USA 101 1087 1092 10.1073/pnas.0304827101 1:CAS:528:DC%2BD2cXhtFSkt7k%3D 14732702 (Pubitemid 38160588)
38. DH Lin H Sterling KM Lerea G Giebisch WH Wang 2002 Protein kinase C (PKC)-induced phosphorylation of ROMK1 is essential for the surface expression of ROMK1 channels J Biol Chem 277 44278 44284 10.1074/jbc.M203702200 1:CAS:528:DC%2BD38Xos1akt7g%3D 12221079 (Pubitemid 36157861)
39. E Nesti B Everill AD Morielli 2004 Endocytosis as a mechanism for tyrosine kinase-dependent suppression of a voltage-gated potassium channel Mol Biol Cell 15 4073 4088 10.1091/mbc.E03-11-0788 1:CAS:528:DC%2BD2cXnt1eksLc%3D 15215309 (Pubitemid 39122013)
40. KA Delaney MM Murph LM Brown H Radhakrishna 2002 Transfer of M2 muscarinic acetylcholine receptors to clathrin-derived early endosomes following clathrin-independent endocytosis J Biol Chem 277 33439 33446 10.1074/jbc.M205293200 1:CAS:528:DC%2BD38Xnt1SksLk%3D 12093817 (Pubitemid 34984867)
41. O Staub H Abriel P Plant T Ishikawa V Kanelis R Saleki JD Horisberger L Schild D Rotin 2000 Regulation of the epithelial Na+ channel by Nedd4 and ubiquitination Kidney Int 57 809 811 10.1046/j.1523-1755.2000.00919.x 1:CAS:528:DC%2BD3cXktFGgsbs%3D 10720933 (Pubitemid 30434770)
42. WZ Zeng V Babich B Ortega R Quigley SJ White PA Welling CL Huang 2002 Evidence for endocytosis of ROMK potassium channel via clathrin-coated vesicles Am J Physiol Renal Physiol 283 F630 639 12217853
43. WS Choi A Khurana R Mathur V Viswanathan DF Steele D Fedida 2005 Kv1.5 surface expression is modulated by retrograde trafficking of newly endocytosed channels by the dynein motor Circ Res 97 363 371 10.1161/01.RES.0000179535. 06458.f8 1:CAS:528:DC%2BD2MXntlSiurY%3D 16051887 (Pubitemid 41216141)
44. K Hu CS Huang YN Jan LY Jan 2003 ATP-sensitive potassium channel traffic regulation by adenosine and protein kinase C Neuron 38 417 432 10.1016/S0896-6273(03)00256-3 1:CAS:528:DC%2BD3sXjvFOrsL8%3D 12741989 (Pubitemid 36579144)
45. D Herring R Huang M Singh GH Dillon NJ Leidenheimer 2005 PKC modulation of GABAA receptor endocytosis and function is inhibited by mutation of a dileucin motif within the receptor beta 2 subunit Neuropharmacology 48 181 194 10.1016/j.neuropharm.2004.09.015 1:CAS:528:DC%2BD2MXhtFOksr0%3D 15695157 (Pubitemid 40208254)
46. JY Lan VA Skeberdis T Jover SY Grooms Y Lin RC Araneda X Zheng MVL Bennet RS Zukin 2001 Protein kinase C modulates NMDA receptor trafficking and gating Nat Neurosci 4 382 390 10.1038/86028 1:CAS:528:DC%2BD3MXitlKjs7Y%3D 11276228 (Pubitemid 32260114)
47. Y Lin T Jover-Mangual J Wong MVL Bennet RS Zukin 2006 PSD-95 and PKC converge in regulating NMDA receptor trafficking and gating Proc Natl Acad Sci USA 103 19902 19907 10.1073/pnas.0609924104 1:CAS:528:DC%2BD2sXivVOqsA%3D%3D 17179037 (Pubitemid 46037528)
48. H Sun XQ Hu EM Moradel FF Weight L Zhang 2003 Modulation of 5-HT3 receptor-mediated response and trafficking by activation of protein kinase C J Biol Chem 278 34150 34157 10.1074/jbc.M303584200 1:CAS:528:DC%2BD3sXmvVCqsrY%3D 12791692 (Pubitemid 37553256)
49. Kr, and the underlying hERG ion channel Basic Res Cardiol 99 279 287 10.1007/s00395-004-0474-7 1:CAS:528:DC%2BD2cXmtFGitr0%3D 15221346
50. JS Bian TV McDonald 2007 Phosphatidylinositol 4, 5-bisphosphate interactions with the HERG K + channel Pflügers Arch Eur J Physiol 455 105 113 10.1007/s00424-007-0292-5 1:CAS:528:DC%2BD2sXhtVeisL%2FK (Pubitemid 47403986)
51. SG Priori C Napolitano V Paganini F Cantu PJ Schwatz 1997 Molecular biology of the long QT syndrome: impact on management Pacing Clin Electrophysiol 20 2052 2057 10.1111/j.1540-8159.1997.tb03626.x 1:STN:280:DyaK2svhvVGntA%3D%3D 9272507 (Pubitemid 27345637)
52. Y Nishizuka 1992 Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C Science 258 607 614 10.1126/science.1411571 1:CAS:528:DyaK38XmsVyqsbo%3D 1411571