메뉴 건너뛰기




Volumn 287, Issue 42, 2012, Pages 35556-35564

Intracellular interaction of interleukin (IL)-32α with protein kinase Cε (PKCε) and STAT3 protein augments IL-6 production in THP-1 promonocytic cells

Author keywords

[No Author keywords available]

Indexed keywords

CELL LINES; DOSE-DEPENDENT MANNER; EXPRESSION SYSTEM; IL-6 EXPRESSION; PHORBOL 12 MYRISTATE 13 ACETATES; PROINFLAMMATORY CYTOKINES; PROTEIN KINASE C; SIGNALING ACTIVITY;

EID: 84867426764     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.400911     Document Type: Article
Times cited : (52)

References (52)
  • 5
    • 67349238650 scopus 로고    scopus 로고
    • Molecular characterization of IL-32 in human endothelial cells
    • Kobayashi, H., and Lin, P. C. (2009) Molecular characterization of IL-32 in human endothelial cells. Cytokine 46, 351-358
    • (2009) Cytokine , vol.46 , pp. 351-358
    • Kobayashi, H.1    Lin, P.C.2
  • 9
    • 68249158099 scopus 로고    scopus 로고
    • A proinflammatory cytokine interleukin-32β promotes the production of an anti-inflammatory cytokine interleukin-10
    • Kang, J. W., Choi, S. C., Cho, M. C., Kim, H. J., Kim, J. H., Lim, J. S., Kim, S. H., Han, J. Y., and Yoon, D. Y. (2009) A proinflammatory cytokine interleukin-32β promotes the production of an anti-inflammatory cytokine interleukin-10. Immunology 128, e532-e540
    • (2009) Immunology , vol.128
    • Kang, J.W.1    Choi, S.C.2    Cho, M.C.3    Kim, H.J.4    Kim, J.H.5    Lim, J.S.6    Kim, S.H.7    Han, J.Y.8    Yoon, D.Y.9
  • 11
    • 79953301760 scopus 로고    scopus 로고
    • Overexpression of IL-32α increases natural killer cell-mediated killing through up-regulation of Fas and UL16-binding protein 2 (ULBP2) expression in human chronic myeloid leukemia cells
    • Cheon, S., Lee, J. H., Park, S., Bang, S. I., Lee, W. J., Yoon, D. Y., Yoon, S. S., Kim, T., Min, H., Cho, B. J., Lee, H. J., Lee, K. W., Jeong, S. H., Park, H., and Cho, D. (2011) Overexpression of IL-32α increases natural killer cell-mediated killing through up-regulation of Fas and UL16-binding protein 2 (ULBP2) expression in human chronic myeloid leukemia cells. J. Biol. Chem. 286, 12049-12055
    • (2011) J. Biol. Chem. , vol.286 , pp. 12049-12055
    • Cheon, S.1    Lee, J.H.2    Park, S.3    Bang, S.I.4    Lee, W.J.5    Yoon, D.Y.6    Yoon, S.S.7    Kim, T.8    Min, H.9    Cho, B.J.10    Lee, H.J.11    Lee, K.W.12    Jeong, S.H.13    Park, H.14    Cho, D.15
  • 12
  • 13
    • 84857267860 scopus 로고    scopus 로고
    • Interleukin 32 (IL-32) contains a typical α-helix bundle structure that resembles focal adhesion targeting region of focal adhesion kinase 1
    • Heinhuis, B., Koenders, M. I., van den Berg, W. B., Netea, M. G., Dinarello, C. A., and Joosten, L. A. (2012) Interleukin 32 (IL-32) contains a typical α-helix bundle structure that resembles focal adhesion targeting region of focal adhesion kinase 1. J. Biol. Chem. 287, 5733-5743
    • (2012) J. Biol. Chem. , vol.287 , pp. 5733-5743
    • Heinhuis, B.1    Koenders, M.I.2    Van Den Berg, W.B.3    Netea, M.G.4    Dinarello, C.A.5    Joosten, L.A.6
  • 14
    • 0028811653 scopus 로고
    • Protein kinase C: Structure, function, and regulation
    • Newton, A. C. (1995) Protein kinase C: structure, function, and regulation. J. Biol. Chem. 270, 28495-28498
    • (1995) J. Biol. Chem. , vol.270 , pp. 28495-28498
    • Newton, A.C.1
  • 15
    • 0034161531 scopus 로고    scopus 로고
    • Regulation of Jak2 tyrosine kinase by protein kinase C during macrophage differentiation of IL-3-dependent myeloid progenitor cells
    • Kovanen, P. E., Junttila, I., Takaluoma, K., Saharinen, P., Valmu, L., Li, W., and Silvennoinen, O. (2000) Regulation of Jak2 tyrosine kinase by protein kinase C during macrophage differentiation of IL-3-dependent myeloid progenitor cells. Blood 95, 1626-1632 (Pubitemid 30120822)
    • (2000) Blood , vol.95 , Issue.5 , pp. 1626-1632
    • Kovanen, P.E.1    Junttila, I.2    Takaluoma, K.3    Saharinen, P.4    Valmu, L.5    Li, W.6    Silvennoinen, O.7
  • 16
    • 0030878316 scopus 로고    scopus 로고
    • Protein kinase C in erythroid and megakaryocytic differentiation: Possible role in lineage determination
    • DOI 10.1016/S0167-4889(97)00051-7, PII S0167488997000517
    • Lumelsky, N. L., and Schwartz, B. S. (1997) Protein kinase C in erythroid and megakaryocytic differentiation: possible role in lineage determination. Biochim. Biophys. Acta 1358, 79-92 (Pubitemid 27365978)
    • (1997) Biochimica et Biophysica Acta - Molecular Cell Research , vol.1358 , Issue.1 , pp. 79-92
    • Lumelsky, N.L.1    Schwartz, B.S.2
  • 17
    • 0027292678 scopus 로고
    • Phorbol ester-induced myeloid differentiation is mediated by protein kinase C-α and -δ and not by protein kinase C-βII, -ε, -ζ, and -η
    • Mischak, H., Pierce, J. H., Goodnight, J., Kazanietz, M. G., Blumberg, P. M., and Mushinski, J. F. (1993) Phorbol ester-induced myeloid differentiation is mediated by protein kinase Cα and -δ and not by protein kinase CßII, -ε, -ζ, and -η. J. Biol. Chem. 268, 20110-20115 (Pubitemid 23278909)
    • (1993) Journal of Biological Chemistry , vol.268 , Issue.27 , pp. 20110-20115
    • Mischak, H.1    Pierce, J.H.2    Goodnight, J.3    Kazanietz, M.G.4    Blumberg, P.M.5    Mushinski, J.F.6
  • 18
    • 0028168429 scopus 로고
    • Protein kinase Cβ is required for macrophage differentiation of human HL-60 leukemia cells
    • Tonetti, D. A., Henning-Chubb, C., Yamanishi, D. T., and Huberman, E. (1994) Protein kinase Cβ is required for macrophage differentiation of human HL-60 leukemia cells. J. Biol. Chem. 269, 23230-23235
    • (1994) J. Biol. Chem. , vol.269 , pp. 23230-23235
    • Tonetti, D.A.1    Henning-Chubb, C.2    Yamanishi, D.T.3    Huberman, E.4
  • 19
    • 0344413747 scopus 로고    scopus 로고
    • Protein kinase C epsilon: A new target to control inflammation and immune-mediated disorders
    • DOI 10.1016/S1357-2725(03)00210-3
    • Aksoy, E., Goldman, M., and Willems, F. (2004) Protein kinase Cε: a new target to control inflammation and immune-mediated disorders. Int. J. Biochem. Cell Biol. 36, 183-188 (Pubitemid 37487754)
    • (2004) International Journal of Biochemistry and Cell Biology , vol.36 , Issue.2 , pp. 183-188
    • Aksoy, E.1    Goldman, M.2    Willems, F.3
  • 20
    • 36749009773 scopus 로고    scopus 로고
    • The roles of PKCδ and ε isoenzymes in the regulation of myocardial ischaemia/reperfusion injury
    • DOI 10.1042/BST0351040
    • Churchill, E. N., and Mochly-Rosen, D. (2007) The roles of PKCδ and -ε isoenzymes in the regulation of myocardial ischemia/reperfusion injury. Biochem. Soc. Trans. 35, 1040-1042 (Pubitemid 350206423)
    • (2007) Biochemical Society Transactions , vol.35 , Issue.5 , pp. 1040-1042
    • Churchill, E.N.1    Mochly-Rosen, D.2
  • 21
    • 48249144457 scopus 로고    scopus 로고
    • Protein kinase Cε: Function in neurons
    • Shirai, Y., Adachi, N., and Saito, N. (2008) Protein kinase Cε: function in neurons. FEBS J. 275, 3988-3994
    • (2008) FEBS J. , vol.275 , pp. 3988-3994
    • Shirai, Y.1    Adachi, N.2    Saito, N.3
  • 22
    • 37249054348 scopus 로고    scopus 로고
    • Nociceptive and behavioural sensitisation by protein kinase Cε signalling in the CNS
    • DOI 10.1111/j.1471-4159.2007.04986.x
    • Van Kolen, K., Pullan, S., Neefs, J. M., and Dautzenberg, F. M. (2008) Nociceptive and behavioral sensitization by protein kinase Cε signaling in the CNS. J. Neurochem. 104, 1-13 (Pubitemid 350265058)
    • (2008) Journal of Neurochemistry , vol.104 , Issue.1 , pp. 1-13
    • Van Kolen, K.1    Pullan, S.2    Neefs, J.-M.3    Dautzenberg, F.M.4
  • 23
    • 36749075159 scopus 로고    scopus 로고
    • Mitochondrial protein kinase Cε (PKCε): Emerging role in cardiac protection from ischaemic damage
    • DOI 10.1042/BST0351052
    • Budas, G. R., and Mochly-Rosen, D. (2007) Mitochondrial protein kinase Cε (PKCε): emerging role in cardiac protection from ischemic damage. Biochem. Soc. Trans. 35, 1052-1054 (Pubitemid 350206427)
    • (2007) Biochemical Society Transactions , vol.35 , Issue.5 , pp. 1052-1054
    • Budas, G.R.1    Mochly-Rosen, D.2
  • 24
    • 28444449793 scopus 로고    scopus 로고
    • Intracellular signaling pathways that regulate behavioral responses to ethanol
    • DOI 10.1016/j.pharmthera.2005.07.004, PII S0163725805001592
    • Newton, P. M., and Messing, R. O. (2006) Intracellular signaling pathways that regulate behavioral responses to ethanol. Pharmacol. Ther. 109, 227-237 (Pubitemid 41740823)
    • (2006) Pharmacology and Therapeutics , vol.109 , Issue.1-2 , pp. 227-237
    • Newton, P.M.1    Messing, R.O.2
  • 27
    • 41749114717 scopus 로고    scopus 로고
    • Amygdala protein kinase C epsilon regulates corticotropin-releasing factor and anxiety-like behavior
    • DOI 10.1111/j.1601-183X.2007.00356.x
    • Lesscher, H. M., McMahon, T., Lasek, A. W., Chou, W. H., Connolly, J., Kharazia, V., and Messing, R. O. (2008) Amygdala protein kinase Cε regulates corticotropin-releasing factor and anxiety-like behavior. Genes Brain Behav. 7, 323-333 (Pubitemid 351490237)
    • (2008) Genes, Brain and Behavior , vol.7 , Issue.3 , pp. 323-333
    • Lesscher, H.M.B.1    McMahon, T.2    Lasek, A.W.3    Chou, W.-H.4    Connolly, J.5    Kharazia, V.6    Messing, R.O.7
  • 28
    • 34250669166 scopus 로고    scopus 로고
    • Protein kinase Cε makes the life and death decision
    • DOI 10.1016/j.cellsig.2007.04.008, PII S0898656807001246
    • Basu, A., and Sivaprasad, U. (2007) Protein kinase Cε makes the life and death decision. Cell. Signal. 19, 1633-1642 (Pubitemid 46935437)
    • (2007) Cellular Signalling , vol.19 , Issue.8 , pp. 1633-1642
    • Basu, A.1    Sivaprasad, U.2
  • 29
    • 61649084727 scopus 로고    scopus 로고
    • Protein kinase Cε: An oncogene and emerging tumor biomarker
    • Gorin, M. A., and Pan, Q. (2009) Protein kinase Cε: an oncogene and emerging tumor biomarker. Mol. Cancer 8, 9
    • (2009) Mol. Cancer , vol.8 , pp. 9
    • Gorin, M.A.1    Pan, Q.2
  • 30
    • 0033258518 scopus 로고    scopus 로고
    • Expression of PKCη in NIH-3T3 cells promotes production of the proinflammatory cytokine interleukin-6
    • Fima, E., Shahaf, G., Hershko, T., Apte, R. N., and Livneh, E. (1999) Expression of PKCη in NIH-3T3 cells promotes production of the proinflammatory cytokine interleukin-6. Eur. Cytokine Netw. 10, 491-500
    • (1999) Eur. Cytokine Netw. , vol.10 , pp. 491-500
    • Fima, E.1    Shahaf, G.2    Hershko, T.3    Apte, R.N.4    Livneh, E.5
  • 31
    • 0029944290 scopus 로고    scopus 로고
    • Human eotaxin is a specific chemoattractant for eosinophil cells and provides a new mechanism to explain tissue eosinophilia
    • DOI 10.1038/nm0496-449
    • Garcia-Zepeda, E. A., Rothenberg, M. E., Ownbey, R. T., Celestin, J., Leder, P., and Luster, A. D. (1996) Human eotaxin is a specific chemoattractant for eosinophil cells and provides a new mechanism to explain tissue eosinophilia. Nat. Med. 2, 449-456 (Pubitemid 26193013)
    • (1996) Nature Medicine , vol.2 , Issue.4 , pp. 449-456
    • Garcia-Zepeda, E.A.1    Rothenberg, M.E.2    Ownbey, R.T.3    Celestin, J.4    Leder, P.5    Luster, A.D.6
  • 32
    • 0034922727 scopus 로고    scopus 로고
    • Calcitonin induces IL-6 production via both PKA and PKC pathways in the pituitary folliculo-stellate cell line
    • DOI 10.1210/en.142.8.3563
    • Kiriyama, Y., Tsuchiya, H., Murakami, T., Satoh, K., and Tokumitsu, Y. (2001) Calcitonin induces IL-6 production via both PKA and PKC pathways in the pituitary folliculostellate cell line. Endocrinology 142, 3563-3569 (Pubitemid 32681766)
    • (2001) Endocrinology , vol.142 , Issue.8 , pp. 3563-3569
    • Kiriyama, Y.1    Tsuchiya, H.2    Murakami, T.3    Satoh, K.4    Tokumitsu, Y.5
  • 33
    • 33847351136 scopus 로고    scopus 로고
    • The JAK-STAT signaling pathway: Input and output integration
    • Murray, P. J. (2007) The JAK-STAT signaling pathway: input and output integration. J. Immunol. 178, 2623-2629
    • (2007) J. Immunol. , vol.178 , pp. 2623-2629
    • Murray, P.J.1
  • 34
    • 78649251953 scopus 로고    scopus 로고
    • STAT3 transcriptional factor activated by reactive oxygen species induces IL-6 in starvation-induced autophagy of cancer cells
    • Yoon, S., Woo, S. U., Kang, J. H., Kim, K., Kwon, M. H., Park, S., Shin, H. J., Gwak, H. S., and Chwae, Y. J. (2010) STAT3 transcriptional factor activated by reactive oxygen species induces IL-6 in starvation-induced autophagy of cancer cells. Autophagy 6, 1125-1138
    • (2010) Autophagy , vol.6 , pp. 1125-1138
    • Yoon, S.1    Woo, S.U.2    Kang, J.H.3    Kim, K.4    Kwon, M.H.5    Park, S.6    Shin, H.J.7    Gwak, H.S.8    Chwae, Y.J.9
  • 36
    • 34547858932 scopus 로고    scopus 로고
    • Protein kinase Cε interacts with Stat3 and regulates its activation that is essential for the development of skin cancer
    • DOI 10.1002/mc.20356
    • Aziz, M. H., Manoharan, H. T., Sand, J. M., and Verma, A. K. (2007) Protein kinase Cε interacts with Stat3 and regulates its activation that is essential for the development of skin cancer. Mol. Carcinog. 46, 646-653 (Pubitemid 47255182)
    • (2007) Molecular Carcinogenesis , vol.46 , Issue.8 , pp. 646-653
    • Aziz, M.H.1    Manoharan, H.T.2    Sand, J.M.3    Verma, A.K.4
  • 37
    • 34548787911 scopus 로고    scopus 로고
    • Protein kinase Cε interacts with signal transducers and activators of transcription 3 (Stat3), phosphorylates Stat3Ser727, and regulates its constitutive activation in prostate cancer
    • DOI 10.1158/0008-5472.CAN-07-1604
    • Aziz, M. H., Manoharan, H. T., Church, D. R., Dreckschmidt, N. E., Zhong, W., Oberley, T. D., Wilding, G., and Verma, A. K. (2007) Protein kinase Cε interacts with signal transducers and activators of transcription 3 (Stat3), phosphorylates Stat3 Ser-727, and regulates its constitutive activation in prostate cancer. Cancer Res. 67, 8828-8838 (Pubitemid 47437459)
    • (2007) Cancer Research , vol.67 , Issue.18 , pp. 8828-8838
    • Aziz, M.H.1    Manoharan, H.T.2    Church, D.R.3    Dreckschmidt, N.E.4    Zhong, W.5    Oberley, T.D.6    Wilding, G.7    Verma, A.K.8
  • 39
    • 12444304581 scopus 로고    scopus 로고
    • Interleukin-32: A cytokine and inducer of TNFα
    • Kim, S. H., Han, S. Y., Azam, T., Yoon, D. Y., and Dinarello, C. A. (2005) Interleukin-32: a cytokine and inducer of TNFα. Immunity 22, 131-142
    • (2005) Immunity , vol.22 , pp. 131-142
    • Kim, S.H.1    Han, S.Y.2    Azam, T.3    Yoon, D.Y.4    Dinarello, C.A.5
  • 40
    • 33751578866 scopus 로고    scopus 로고
    • TLR4-dependent NF-κB activation and mitogen- and stress-activated protein kinase 1-triggered phosphorylation events are central to Helicobacter pylori peptidyl prolyl cis-, trans-isomerase (HP0175)-mediated induction of IL-6 release from macrophages
    • Pathak, S. K., Basu, S., Bhattacharyya, A., Pathak, S., Banerjee, A., Basu, J., and Kundu, M. (2006) TLR4-dependent NF-κB activation and mitogen- and stress-activated protein kinase 1-triggered phosphorylation events are central to Helicobacter pylori peptidylprolyl cis,trans-isomerase (HP0175)-mediated induction of IL-6 release from macrophages. J. Immunol. 177, 7950-7958 (Pubitemid 44846311)
    • (2006) Journal of Immunology , vol.177 , Issue.11 , pp. 7950-7958
    • Pathak, S.K.1    Basu, S.2    Bhattacharyya, A.3    Pathak, S.4    Banerjee, A.5    Basu, J.6    Kundu, M.7
  • 41
    • 0034672092 scopus 로고    scopus 로고
    • Regulation of IL-6 and IL-8 expression in rheumatoid arthritis synovial fibroblasts: The dominant role for NF-κB but not C/EBPβ or c-Jun
    • Georganas, C., Liu, H., Perlman, H., Hoffmann, A., Thimmapaya, B., and Pope, R. M. (2000) Regulation of IL-6 and IL-8 expression in rheumatoid arthritis synovial fibroblasts: the dominant role for NF-κB but not C/EBPβ or c-Jun. J. Immunol. 165, 7199-7206 (Pubitemid 32001197)
    • (2000) Journal of Immunology , vol.165 , Issue.12 , pp. 7199-7206
    • Georganas, C.1    Liu, H.2    Perlman, H.3    Hoffmann, A.4    Thimmapaya, B.5    Pope, R.M.6
  • 44
    • 33744828259 scopus 로고    scopus 로고
    • The linoleic acid derivative DCP-LA selectively activates PKC-ε, possibly binding to the phosphatidylserine binding site
    • DOI 10.1194/jlr.M500329-JLR200
    • Kanno, T., Yamamoto, H., Yaguchi, T., Hi, R., Mukasa, T., Fujikawa, H., Nagata, T., Yamamoto, S., Tanaka, A., and Nishizaki, T. (2006) The linoleic acid derivative DCP-LA selectively activates PKCε, possibly binding to the phosphatidylserine-binding site. J. Lipid Res. 47, 1146-1156 (Pubitemid 43830706)
    • (2006) Journal of Lipid Research , vol.47 , Issue.6 , pp. 1146-1156
    • Kanno, T.1    Yamamoto, H.2    Yaguchi, T.3    Hi, R.4    Mukasa, T.5    Fujikawa, H.6    Nagata, T.7    Yamamoto, S.8    Tanaka, A.9    Nishizaki, T.10
  • 45
    • 78349311836 scopus 로고    scopus 로고
    • Native IL-32 is released from intestinal epithelial cells via a non-classical secretory pathway as a membrane-associated protein
    • Hasegawa, H., Thomas, H. J., Schooley, K., and Born, T. L. (2011) Native IL-32 is released from intestinal epithelial cells via a non-classical secretory pathway as a membrane-associated protein. Cytokine 53, 74-83
    • (2011) Cytokine , vol.53 , pp. 74-83
    • Hasegawa, H.1    Thomas, H.J.2    Schooley, K.3    Born, T.L.4
  • 48
    • 58449128740 scopus 로고    scopus 로고
    • Interleukin-32 promotes osteoclast differentiation but not osteoclast activation
    • Mabilleau, G., and Sabokbar, A. (2009) Interleukin-32 promotes osteoclast differentiation but not osteoclast activation. PLoS ONE 4, e4173
    • (2009) PLoS ONE , vol.4
    • Mabilleau, G.1    Sabokbar, A.2
  • 50
    • 0035474310 scopus 로고    scopus 로고
    • Adaptor proteins in protein kinase C-mediated signal transduction
    • DOI 10.1038/sj.onc.1204778
    • Schechtman, D., and Mochly-Rosen, D. (2001) Adaptor proteins in protein kinase C-mediated signal transduction. Oncogene 20, 6339-6347 (Pubitemid 32977843)
    • (2001) Oncogene , vol.20 , Issue.44 REV. ISS. 5 , pp. 6339-6347
    • Schechtman, D.1    Mochly-Rosen, D.2
  • 51
    • 0033588229 scopus 로고    scopus 로고
    • Protein kinase Cδ associates with and phosphorylates Stat3 in an interleukin-6-dependent manner
    • Jain, N., Zhang, T., Kee, W. H., Li, W., and Cao, X. (1999) Protein kinase Cδ associates with and phosphorylates Stat3 in an interleukin-6-dependent manner. J. Biol. Chem. 274, 24392-24400
    • (1999) J. Biol. Chem. , vol.274 , pp. 24392-24400
    • Jain, N.1    Zhang, T.2    Kee, W.H.3    Li, W.4    Cao, X.5
  • 52
    • 33845439434 scopus 로고    scopus 로고
    • Oncostatin M-induced IL-6 expression in murine fibroblasts requires the activation of protein kinase Cδ
    • Smyth, D. C., Kerr, C., and Richards, C. D. (2006) Oncostatin M-induced IL-6 expression in murine fibroblasts requires the activation of protein kinase Cδ. J. Immunol. 177, 8740-8747 (Pubitemid 44893840)
    • (2006) Journal of Immunology , vol.177 , Issue.12 , pp. 8740-8747
    • Smyth, D.C.1    Kerr, C.2    Richards, C.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.