Molecular Phenotyping of Immune Cells from Young NOD Mice Reveals Abnormal Metabolic Pathways in the Early Induction Phase of Autoimmune Diabetes

PLoS ONE

Volumn 7, Issue 10, 2012, Pages

  Wu, Jian ^a,b,c   Kakoola, Dorothy N ^a,b   Lenchik, Nataliya I ^a,b   Desiderio, Dominic M ^a   Marshall, Dana R ^b,d   Gerling, Ivan C ^a,b  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c CAPITAL MEDICAL UNIVERSITY   (China)

^d MEHARRY MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL; GAMMA INTERFERON; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; HLA C ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 12; INTERLEUKIN 2; MESSENGER RNA; PROGESTERONE; PROTEIN KINASE B; PROTEIN P53; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR;

AKT GENE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BETA ESTRADIOL GENE; CONTROLLED STUDY; EX VIVO STUDY; FEMALE; GENE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; HEPATOCYTE NUCLEAR FACTOR 4ALPHA GENE; HLA C GENE; IMMUNOCOMPETENT CELL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN GENE; IMMUNOPATHOGENESIS; IMMUNOPHENOTYPING; INSULIN DEPENDENT DIABETES MELLITUS; INTERFERON GAMMA GENE; INTERLEUKIN 12 GENE; INTERLEUKIN 15 GENE; INTERLEUKIN 2 GENE; MOUSE; NONHUMAN; ONCOGENE MYC; P53 GENE; PRKCA GENE; PROGESTERONE GENE; PROTEIN EXPRESSION; TRANSFORMING GROWTH FACTOR BETA1 GENE; TUMOR NECROSIS FACTOR GENE; YWHAZ GENE;

ANALYSIS OF VARIANCE; ANIMALS; CLUSTER ANALYSIS; DIABETES MELLITUS, TYPE 1; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; GENE REGULATORY NETWORKS; HUMANS; LEUKOCYTES; METABOLIC NETWORKS AND PATHWAYS; MICE; MICE, INBRED C57BL; MICE, INBRED NOD; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHENOTYPE; PROTEOME; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPLEEN; TIME FACTORS; TRANSCRIPTOME;

EID: 84867426756     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0046941     Document Type: Article

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