Anthracycline inhibits recruitment of hypoxia-inducible transcription factors and suppresses tumor cell migration and cardiac angiogenic response in the host

Journal of Biological Chemistry

Volumn 287, Issue 42, 2012, Pages 34866-34882

  Tanaka, Tetsuhiro ^a,b   Yamaguchis, Junna ^b   Shojis, Kumi ^b   Nangakus, Masaomi ^b  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELLULAR HYPOXIA RESPONSE; CHEMICAL TEMPLATES; CHEMOTHERAPEUTIC AGENTS; DOWN-REGULATION; DOXORUBICIN; HEART FAILURE; HETERODIMERS; HYPOXIA-INDUCIBLE FACTORS; HYPOXIA-INDUCIBLE TRANSCRIPTION FACTORS; HYPOXIC ENVIRONMENTS; LYSYL OXIDASE; PLEIOTROPIC EFFECTS; RENAL CELL CARCINOMA; TARGET GENES; TOPOISOMERASES; TRANSCRIPTIONAL RESPONSE; TUMOR CELL MIGRATION; TUMOR TISSUES; TUMOR XENOGRAFTS;

TRANSCRIPTION FACTORS;

TUMORS;

ANGIOPOIETIN 1; ANGIOPOIETIN 2; BRAIN NATRIURETIC PEPTIDE; DAUNORUBICIN; DOXORUBICIN; ERYTHROPOIETIN; ETOPOSIDE; HEME OXYGENASE 1; HETERODIMER; HYPOXIA INDUCIBLE FACTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IMMUNOGLOBULIN G; ISOPRENALINE; PROSTAGLANDIN SYNTHASE; PROTEIN LYSINE 6 OXIDASE; PROTEIN LYSINE 6 OXIDASE LIKE 2; PROTEIN LYSINE 6 OXIDASE LIKE 4; UNCLASSIFIED DRUG; VASCULOTROPIN; VON HIPPEL LINDAU PROTEIN;

ANEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CARDIOMYOPATHY; CELL MIGRATION; CONTROLLED STUDY; DISEASE MODEL; DOWN REGULATION; ENHANCER REGION; FEMALE; HEART FAILURE; HUMAN; HUMAN CELL; INHIBITION KINETICS; KIDNEY CARCINOMA; MALE; MOUSE; NONHUMAN; PLEIOTROPY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FAMILY; PROTEIN INDUCTION; TUMOR XENOGRAFT;

AMINO ACID OXIDOREDUCTASES; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CARCINOMA, RENAL CELL; CARDIOMYOPATHIES; CELL HYPOXIA; CELL MOVEMENT; DOXORUBICIN; HELA CELLS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; KIDNEY NEOPLASMS; MICE; MICE, NUDE; MYOCARDIUM; NEOPLASM PROTEINS; NEOPLASM TRANSPLANTATION; NEOVASCULARIZATION, PATHOLOGIC; RATS; RATS, SPRAGUE-DAWLEY; RESPONSE ELEMENTS; TRANSPLANTATION, HETEROLOGOUS;

EID: 84867425973     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.374587     Document Type: Article

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