Activation of p53 enhances apoptosis and insulin resistance in a rat model of alcoholic liver disease

Journal of Hepatology

Volumn 54, Issue 1, 2011, Pages 164-172

  Derdak, Zoltan ^a,c   Lang, Charles H ^b   Villegas, Kristine A ^a   Tong, Ming ^a   Mark, Nicholas M ^a   De La Monte, Suzanne M ^a   Wands, Jack R ^a  

^a BROWN UNIVERSITY   (United States)

^b PENN STATE COLLEGE OF MEDICINE   (United States)

^c BROWN UNIVERSITY   (United States)

Author keywords

Fructose 2,6 bisphosphate; Hepatocellular death; PTEN; PUMA; TIGAR

Indexed keywords

FRUCTOSE 2,6 BISPHOSPHATE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN P53; PUMA PROTEIN;

ALCOHOL LIVER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL SURVIVAL; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; FATTY LIVER; GLUCONEOGENESIS; GLYCOLYSIS; HISTOPATHOLOGY; INSULIN RESISTANCE; LIVER INJURY; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT;

ALANINE TRANSAMINASE; ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CASPASE 3; DISEASE MODELS, ANIMAL; DNA DAMAGE; DNA, MITOCHONDRIAL; FATTY LIVER, ALCOHOLIC; FRUCTOSEDIPHOSPHATES; GLUCONEOGENESIS; INSULIN RESISTANCE; LIVER DISEASES, ALCOHOLIC; MALE; OXIDATIVE STRESS; POLY(ADP-RIBOSE) POLYMERASES; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RATS; RATS, INBRED F344; RATS, LONG-EVANS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SPECIES SPECIFICITY; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TUMOR SUPPRESSOR PROTEIN P53;

EID: 78649632422     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2010.08.007     Document Type: Article

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