Neutrophil elastase modulates cytokine expression: Contribution to host defense against pseudomonas aeruginosa-induced pneumonia

Journal of Biological Chemistry

Volumn 287, Issue 42, 2012, Pages 34883-34894

  Benabid, Rym ^a   Wartelle, Julien ^a   Malleret, Laurette ^a   Guyot, Nicolas ^a   Gangloff, Sophie ^a   Lebargy, François ^a   Belaaouaj, Azzaq ^a  

^a REIMS UNIVERSITY HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL INFECTIONS; CYTOKINE EXPRESSION; ELASTASE; EXTRACELLULAR; HOST DEFENSE; IN-VIVO; MUTANT MICE; P.AERUGINOSA; PROINFLAMMATORY CYTOKINES; SERINE PROTEASE; THERAPEUTIC STRATEGY; TOLL-LIKE RECEPTOR 4; TRANSCRIPT LEVEL;

AMINO ACIDS; BACTERIA; MAMMALS;

ENZYME INHIBITION;

INTERLEUKIN 6; LEUKOCYTE ELASTASE; MACROPHAGE INFLAMMATORY PROTEIN 2; MESSENGER RNA; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVITY; ENZYME DEFICIENCY; ENZYME INHIBITION; ENZYME PURIFICATION; ENZYME REGULATION; ENZYME RELEASE; GENE EXPRESSION REGULATION; HOST RESISTANCE; IN VIVO STUDY; LUNG PARENCHYMA; MORTALITY; MOUSE; MOUSE MUTANT; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PSEUDOMONAS PNEUMONIA; TRANSCRIPTION REGULATION;

ANIMALS; CYTOKINES; GENE EXPRESSION REGULATION; IMMUNITY, INNATE; LEUKOCYTE ELASTASE; LUNG; MICE; MICE, KNOCKOUT; PNEUMONIA, BACTERIAL; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; TOLL-LIKE RECEPTOR 4;

EID: 84867411373     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.361352     Document Type: Article

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