Mismatch repair deficiency: A temozolomide resistance factor in medulloblastoma cell lines that is uncommon in primary medulloblastoma tumours

British Journal of Cancer

Volumn 107, Issue 8, 2012, Pages 1399-1408

  Von Bueren, A O ^a,b,c   Bacolod, M D ^d   Hagel, C ^a   Heinimann, K ^e   Fedier, A ^f   Kordes, U ^a   Pietsch, T ^g   Koster, J ^h   Grotzer, M A ^b   Friedman, H S ^d   Marra, G ^c   Kool, M ⁱ   Rutkowski, S ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b UNIVERSITY CHILDREN S HOSPITAL   (Switzerland)

^c UNIVERSITY OF ZURICH   (Switzerland)

^d DUKE UNIVERSITY MEDICAL CENTER   (United States)

^e UNIVERSITY OF BASEL   (Switzerland)

^f UNIVERSITÄTSSPITAL ZÜRICH   (Switzerland)

^g UNIVERSITY OF BONN   (Germany)

^h ACADEMIC MEDICAL CENTER   (Netherlands)

ⁱ GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

Drug resistance; Medulloblastoma; Mismatch repair; Temozolomide

Indexed keywords

6 O BENZYLGUANINE; 6 O METHYLGUANINE; DNA METHYLTRANSFERASE; PROTEIN MLH1; TEMOZOLOMIDE;

ARTICLE; CANCER CELL CULTURE; CANCER SURVIVAL; CELL KILLING; CHILD; CLONOGENIC ASSAY; CYTOTOXICITY; DNA METHYLATION; DNA MICROARRAY; DNA SEQUENCE; DRUG EFFECT; DRUG POTENCY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IC 50; IMMUNOHISTOCHEMISTRY; MALE; MEDULLOBLASTOMA; MISMATCH REPAIR; MLH1 GENE; MUTATION; ONCOGENE; PRESCHOOL CHILD; PRIMARY TUMOR; PRIORITY JOURNAL; PROMOTER REGION; SCHOOL CHILD; TISSUE SECTION; WESTERN BLOTTING;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANTINEOPLASTIC AGENTS, ALKYLATING; CELL LINE, TUMOR; CEREBELLAR NEOPLASMS; CHILD; CHILD, PRESCHOOL; DACARBAZINE; DNA MISMATCH REPAIR; DNA MODIFICATION METHYLASES; DNA REPAIR ENZYMES; DRUG RESISTANCE, NEOPLASM; FEMALE; HUMANS; MALE; MEDULLOBLASTOMA; NUCLEAR PROTEINS; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; TUMOR SUPPRESSOR PROTEINS;

EID: 84867397241     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2012.403     Document Type: Article

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