Asociation of manganese superoxide dismutase and glutathione S-transferases genotypes with myocardial infarction in patients with type 2 diabetes mellitus

Diabetes Research and Clinical Practice

Volumn 98, Issue 1, 2012, Pages 144-150

  Kariž, Stojan ^a   Nikolajević Starčević, Jovana ^b   Petrovič, Daniel ^b  

^a Izola General Hospital   (Slovenia)

^b UNIVERSITY OF LJUBLJANA   (Slovenia)

Author keywords

Glutathione S transferase; Manganese superoxide dismutase; Myocardial infarction; Oxidative stress; Type 2 diabetes mellitus

Indexed keywords

C REACTIVE PROTEIN; CHOLESTEROL; D DIMER; FIBRINOGEN; GLUCOSE; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE P1; GLUTATHIONE TRANSFERASE T1; HIGH DENSITY LIPOPROTEIN; INSULIN; LOW DENSITY LIPOPROTEIN; MANGANESE SUPEROXIDE DISMUTASE; TRIACYLGLYCEROL; ALANINE; BIOLOGICAL MARKER; GLUTATHIONE S-TRANSFERASE M1; GLUTATHIONE S-TRANSFERASE T1; GLUTATHIONE TRANSFERASE; GSTP1 PROTEIN, HUMAN; LIPID; SUPEROXIDE DISMUTASE; VALINE;

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; BODY MASS; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DISEASE DURATION; DNA POLYMORPHISM; FEMALE; FIBRINOGEN BLOOD LEVEL; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC RISK; GENOTYPE; GLUCOSE BLOOD LEVEL; HAPLOTYPE; HEART INFARCTION; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; INSULIN TREATMENT; MAJOR CLINICAL STUDY; MALE; MULTIPLEX POLYMERASE CHAIN REACTION; NON INSULIN DEPENDENT DIABETES MELLITUS; OXIDATION REDUCTION STATE; POLYMERASE CHAIN REACTION; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN POLYMORPHISM; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK ASSESSMENT; RISK FACTOR; SEX DIFFERENCE; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING; TRIACYLGLYCEROL BLOOD LEVEL; BLOOD; CAUCASIAN; CROSS-SECTIONAL STUDY; DIABETIC ANGIOPATHY; GENETIC PREDISPOSITION; GENETICS; METABOLISM; MIDDLE AGED; OXIDATIVE STRESS; SLOVENIA; STATISTICAL MODEL;

ALANINE; BIOLOGICAL MARKERS; BLOOD GLUCOSE; CROSS-SECTIONAL STUDIES; DIABETES MELLITUS, TYPE 2; DIABETIC ANGIOPATHIES; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; GLUTATHIONE S-TRANSFERASE PI; GLUTATHIONE TRANSFERASE; HUMANS; LIPIDS; LOGISTIC MODELS; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; SLOVENIA; SUPEROXIDE DISMUTASE; VALINE;

EID: 84867395632     PISSN: 01688227     EISSN: 18728227     Source Type: Journal    
DOI: 10.1016/j.diabres.2012.07.003     Document Type: Article

References (46)

1. Laakso M. Heart in diabetes: a microvascular disease. Diabetes Care 2011, 34(Suppl. 2):S145-S149.
2. Johansen J.S., Harris A.K., Rychly D.J., Ergul A. Oxidative stress and the use of antioxidants in diabetes: linking basic science to clinical practice. Cardiovasc Diabetol 2005, 4:5.
3. Kaneto H., Katakami N., Matsuhisa M., Matsuoka T.A. Role of reactive oxygen species in the progression of type 2 diabetes and atherosclerosis. Mediators Inflamm 2010 2010, 453892.
4. Guidot D.M., McCord J.M., Wright R.M., Repine J.E. Absence of electron transport (Rho 0 state) restores growth of a manganese-superoxide dismutase-deficient Saccharomyces cerevisiae in hyperoxia: evidence for electron transport as a major source of superoxide generation in vivo. J Biol Chem 1993, 268:26699-26703.
5. Faraci F.M., Didion S.P. Vascular protection: superoxide dismutase isoforms in the vessel wall. Arterioscler Thromb Vasc Biol 2004, 24:1367-1373.
6. Wispe J.R., Clark J.C., Burhans M.S., Kropp K.E., Korfhagen T.R., Whitsett J.A. Synthesis and processing of the precursor for human mangano-superoxide dismutase. Biochim Biophys Acta 1989, 994:30-36.
7. Nomiyama T., Tanaka Y., Piao L., Nagasaka K., Sakai K., Ogihara T., et al. The polymorphism of manganese superoxide dismutase is associated with diabetic nephropathy in Japanese type 2 diabetic patients. J Hum Genet 2003, 48:138-141.
8. Fujimoto H., Taguchi J., Imai Y., Ayabe S., Hashimoto H., Kobayashi H., et al. Manganese superoxide dismutase polymorphism affects the oxidized low-density lipoprotein-induced apoptosis of macrophages and coronary artery disease. Eur Heart J 2008, 29:1267-1274.
9. Shimoda-Matsubayashi S., Matsumine H., Kobayashi T., Nakagawa-Hattori Y., Shimizu Y., Mizuno Y. Structural dimorphism in the mitochondrial targeting sequence in the human manganese superoxide dismutase gene. Biochem Biophys Res Commun 1996, 226:561-565.
10. Sutton A., Khoury H., Prip-Buus C., Cepanec C., Pessayre D., Degoul F. The Ala16Val genetic dimorphism modulates the import of human manganese superoxide dismutase into rat liver mitochondria. Pharmacogenetics 2003, 13:145-157.
11. Flekac M., Skrha J., Hilgertova J., Lacinova Z., Jarolimkova M. Gene polymorphisms of superoxide dismutases and catalase in diabetes mellitus. BMC Med Genet 2008, 9:30.
12. Kangas-Kontio T., Vavuli S., Kakko S.J., Penna J., Savolainen E.R., Savolainen M.J., et al. Polymorphism of the manganese superoxide dismutase gene but not of vascular endothelial growth factor gene is a risk factor for diabetic retinopathy. Br J Ophthalmol 2009, 93:1401-1406.
13. Petrovic M.G., Cilensek I., Petrovic D. Manganese superoxide dismutase gene polymorphism (V16A) is associated with diabetic retinopathy in Slovene (Caucasians) type 2 diabetes patients. Dis Markers 2008, 24:59-64.
14. Liu L., Zheng T., Wang N., Wang F., Li M., Jiang J., et al. The manganese superoxide dismutase Val16Ala polymorphism is associated with decreased risk of diabetic nephropathy in Chinese patients with type 2 diabetes. Mol Cell Biochem 2009, 322:87-91.
15. Šantl Letonja M., Letonja M., Nikolajević-Starčević J.N., Petrovič D. Association of manganese superoxide dismutase and glutathione S-transferases genotypes with carotid atherosclerosis in patients with diabetes mellitus type 2. Int Angiol 2012, 31:33-41.
16. Hayes J.D., Pulford D.J. The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance. Crit Rev Biochem Mol Biol 1995, 30:445-600.
17. Josephy P.D. Genetic variations in human glutathione transferase enzymes: significance for pharmacology and toxicology. Hum Genomics Proteomics 2010, 2010:876940.
18. Amer M.A., Ghattas M.H., Abo-Elmatty D.M., Abou-El-Ela S.H. Influence of glutathione S-transferase polymorphisms on type-2 diabetes mellitus risk. Genet Mol Res 2011, 10:3722-3730.
19. Hori M., Oniki K., Ueda K., Goto S., Mihara S., Marubayashi T., et al. Combined glutathione S-transferase T1 and M1 positive genotypes afford protection against Type 2 diabetes in Japanese. Pharmacogenomics 2007, 8:1307-1314.
20. Bid H.K., Konwar R., Saxena M., Chaudhari P., Agrawal C.G., Banerjee M. Association of glutathione S-transferase (GSTM1, T1 and P1) gene polymorphisms with type 2 diabetes mellitus in north Indian population. J Postgrad Med 2010, 56:176-181.
21. Yalin S., Hatungil R., Tamer L., Ates N.A., Dogruer N., Yildirim H., et al. Glutathione S-transferase gene polymorphisms in Turkish patients with diabetes mellitus. Cell Biochem Funct 2007, 25:509-513.
22. Wilson M.H., Grant P.J., Hardie L.J., Wild C.P. Glutathione S-transferase M1 null genotype is associated with a decreased risk of myocardial infarction. FASEB J 2000, 14:791-796.
23. Wilson M.H., Grant P.J., Kain K., Warner D.P., Wild C.P. Association between the risk of coronary artery disease in South Asians and a deletion polymorphism in glutathione S-transferase M1. Biomarkers 2003, 8:43-50.
24. Tamer L., Ercan B., Camsari A., Yildirim H., Cicek D., Sucu N., et al. Glutathione S-transferase gene polymorphism as a susceptibility factor in smoking-related coronary artery disease. Basic Res Cardiol 2004, 99:223-229.
25. Doney A.S., Lee S., Leese G.P., Morris A.D., Palmer C.N. Increased cardiovascular morbidity and mortality in type 2 diabetes is associated with the glutathione S transferase theta-null genotype: a Go-DARTS study. Circulation 2005, 111:2927-2934.
26. Wang J., Zou L., Huang S., Lu F., Lang X., Han L., et al. Genetic polymorphisms of glutathione S-transferase genes GSTM1, GSTT1 and risk of coronary heart disease. Mutagenesis 2010, 25:365-369.
27. Norskov M.S., Frikke-Schmidt R., Loft S., Sillesen H., Grande P., Nordestgaard B.G., et al. Copy number variation in glutathione S-transferases M1 and T1 and ischemic vascular disease: four studies and meta-analyses. Circ Cardiovasc Genet 2011, 4:418-428.
28. Sundberg K., Johansson A.S., Stenberg G., Widersten M., Seidel A., Mannervik B., et al. Differences in the catalytic efficiencies of allelic variants of glutathione transferase P1-1 towards carcinogenic diol epoxides of polycyclic aromatic hydrocarbons. Carcinogenesis 1998, 19:433-436.
29. Palmer C.N., Young V., Ho M., Doney A., Belch J.J. Association of common variation in glutathione S-transferase genes with premature development of cardiovascular disease in patients with systemic sclerosis. Arthritis Rheum 2003, 48:854-855.
30. Park J.H., El Sohemy A., Cornelis M.C., Kim H.A., Kim S.Y., Bae S.C. Glutathione S-transferase M1, T1, and P1 gene polymorphisms and carotid atherosclerosis in Korean patients with rheumatoid arthritis. Rheumatol Int 2004, 24:157-163.
31. Expert Committee on the Diagnosis and Classification of Diabetes Mellitus Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care 2003, 26(Suppl. 1):S5-S20.
32. Alpert J.S., Thygesen K., Antman E., Bassand J.P. Myocardial infarction redefined-a consensus document of The Joint European Society of Cardiology/American College of Cardiology Committee for the redefinition of myocardial infarction. JACC 2000, 36:959-969.
33. Degoul F., Sutton A., Mansouri A., Cepanec C., Degott C., Fromenty B., et al. Homozygosity for alanine in the mitochondrial targeting sequence of superoxide dismutase and risk for severe alcoholic liver disease. Gastroenterology 2001, 120:1468-1474.
34. Arand M., Mühlbauer R., Hengstler J., Jäger E., Fuchs J., Winkler L., et al. A multiplex polymerase chain reaction protocol for the simultaneous analysis of the glutathione S-transferase GSTM1 and GSTT1 polymorphisms. Anal Biochem 1996, 236:184-186.
35. Tian C., Liu T., Fang S., Du X., Jia C. Association of C47T polymorphism in SOD2 gene with coronary artery disease: a case-control study and a meta-analysis. Mol Biol Rep 2012, 39:5269-5276.
36. Tian C., Fang S., Du X., Jia C. Association of the C47T polymorphism in SOD2 with diabetes mellitus and diabetic microvascular complications: a meta-analysis. Diabetologia 2011, 54:803-811.
37. Nemoto M., Nishimura R., Sasaki T., Hiki Y., Miyashita Y., Nishioka M., et al. Genetic association of glutathione peroxidase-1 with coronary artery calcification in type 2 diabetes: a case control study with multi-slice computed tomography. Cardiovasc Diabetol 2007, 7:23.
38. Katakami N., Kaneto H., Matsuoka T.A., Takahara M., Imamura K., Ishibashi F., et al. Accumulation of gene polymorphisms related to oxidative stress is associated with myocardial infarction in Japanese type 2 diabetic patients. Atherosclerosis 2010, 212:534-538.
39. Manfredi S., Calvi D., del Fiandra M., Botto N., Biagini A., Andreassi M.G. Glutathione S-transferase T1- and M1-null genotypes and coronary artery disease risk in patients with Type 2 diabetes mellitus. Pharmacogenomics 2009, 10:29-34.
40. Minelli C., Granell R., Newson R., Rose-Zerilli M.J., Torrent M., Ring S.M., et al. Glutathione-S-transferase genes and asthma phenotypes: a Human Genome Epidemiology (HuGE) systematic review and meta-analysis including unpublished data. Int J Epidemiol 2010, 39:539-562.
41. Garte S., Gaspari L., Alexandrie A.K., Ambrosone C., Autrup H., Autrup J.L., et al. Metabolic gene polymorphism frequencies in control populations. Cancer Epidemiol Biomarkers Prev 2001, 10:1239-1248.
42. Nelson H.H., Wiencke J.K., Christiani D.C., Cheng T.J., Zuo Z.F., Schwartz B.S., et al. Ethnic differences in the prevalence of homozygous deleted genotype of glutathione S-transferase theta. Carcinogenesis 1995, 16:1243-1245.
43. CilenŠek I., Mankoč S., Petrovič M.G., Petrovič D. GSTT1 null genotype is a risk factor for diabetic retinopathy in Caucasians with type 2 diabetes, whereas GSTM1 null genotype might confer protection against retinopathy. Dis Markers 2012, 32:93-99.
44. Cerne J.Z., Pohar-Perme M., Novakovic S., Frkovic-Grazio S., Stegel V., Gersak K. Combined effect of CYP1B1, COMT, GSTP1, and MnSOD genotypes and risk of postmenopausal breast cancer. J Gynecol Oncol 2011, 22:110-119.
45. Watson M.A., Stewart R.K., Smith G.B.J., Massey T.E., Bell D.A. Human glutathione S-transferase P1 polymorphism: relationship to lung tissue enzyme activity and population frequency distribution. Carcinogenesis 1998, 19:275-280.
46. Timofeeva M., Jäger B., Rosenberger A., Sauter W., Wichmann H.E., Bickeböller H., et al. A multiplex real-time PCR method for detection of GSTM1 and GSTT1 copy numbers. Clin Biochem 2009, 42:500-509.