[99mTc]demomedin C, a radioligand based on human gastrin releasing peptide(18-27): Synthesis and preclinical evaluation in gastrin releasing peptide receptor-expressing models

Journal of Medicinal Chemistry

Volumn 55, Issue 19, 2012, Pages 8364-8374

  Nock, Berthold A ^a   Cescato, Renzo ^b   Ketani, Eleni ^a   Waser, Beatrice ^b   Reubi, Jean Claude ^b   Maina, Theodosia ^a  

^a INSTITUTE OF NANOSCIENCE AND NANOTECHNOLOGY   (Greece)

^b UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

DEMOMEDIN C TC 99M; GASTRIN RELEASING PEPTIDE RECEPTOR; NEUROMEDIN C; RADIOLIGAND; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTORADIOGRAPHY; CALCIUM TRANSPORT; CANCER CELL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; TUMOR XENOGRAFT;

AMINO ACID SEQUENCE; ANIMALS; ANURA; AUTORADIOGRAPHY; BINDING, COMPETITIVE; BOMBESIN; BRONCHIAL NEOPLASMS; CALCIUM; CELL LINE, TUMOR; CELL MEMBRANE; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; ILEAL NEOPLASMS; LIGANDS; MALE; MICE; MICE, SCID; MICROSCOPY, FLUORESCENCE; NEOPLASM TRANSPLANTATION; OLIGOPEPTIDES; ORGANOTECHNETIUM COMPOUNDS; PEPTIDE FRAGMENTS; PROSTATIC NEOPLASMS; RADIOPHARMACEUTICALS; RECEPTORS, BOMBESIN; SPECIES SPECIFICITY; STRUCTURE-ACTIVITY RELATIONSHIP; TECHNETIUM; TISSUE DISTRIBUTION; TRANSPLANTATION, HETEROLOGOUS;

EID: 84867352612     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm300741f     Document Type: Article

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