Bombesin antagonist-based radioligands for translational nuclear imaging of gastrin-releasing peptide receptor-positive tumors

Journal of Nuclear Medicine

Volumn 52, Issue 12, 2011, Pages 1970-1978

  Abiraj, Keelara ^a   Mansi, Rosalba ^a   Tamma, Maria Luisa ^a   Fani, Melpomeni ^a   Forrer, Flavio ^a   Nicolas, Guillaume ^a   Cescato, Renzo ^b   Reubi, Jean Claude ^b   Maecke, Helmut R ^a  

^a UNIVERSITY HOSPITAL BASEL   (Switzerland)

^b UNIVERSITY OF BERN   (Switzerland)

Author keywords

Bombesin; Gastrin releasing peptide receptor; PET SPECT tracers; Prostate cancer

Indexed keywords

1,4,7 TRIAZACYCLONONANE, 1 GLUTARIC ACID 4,7 ACETIC ACID MACROGOL DEXTRO PHENYLALANYLGLUTAMINYLTRYPTOPHYLALANYLVALYLGLYCYLHISTIDYLSTATINYLLEUCINE AMIDE GA 68; 4,11 BIS(CARBOXYMETHYL) 1,4,8,11 TETRAAZABICYCLO[6.6.2]HEXADECANE MACROGOL DEXTRO PHENYLALANYLGLUTAMINYLTRYPTOPHYLALANYLVALYLGLYCYLHISTIDYLSTATINYLLEUCINE AMIDE CU 64; 6 CARBOXY 1,4,7,11 TETRAAZAUNDECANE MACROGOL DEXTRO PHENYLALANYLGLUTAMINYLTRYPTOPHYLALANYLVALYLGLYCYLHISTIDYLSTATINYLLEUCINE AMIDE TC 99M; BOMBESIN ANTAGONIST; GASTRIN RELEASING PEPTIDE RECEPTOR; MACROGOL 400; MACROGOL DEXTRO PHENYLALANYLGLUTAMINYLTRYPTOPHYLALANYLVALYLGLYCYLHISTIDYLSTATINYLLEUCINE AMIDE; RADIOLIGAND; TETRAXETAN MACROGOL DEXTRO PHENYLALANYLGLUTAMINYLTRYPTOPHYLALANYLVALYLGLYCYLHISTIDYLSTATINYLLEUCINE AMIDE IN 111; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CALCIUM MOBILIZATION; CALCIUM TRANSPORT; COMPUTER ASSISTED EMISSION TOMOGRAPHY; COMPUTER ASSISTED TOMOGRAPHY; CONJUGATION; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG UPTAKE; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IC 50; IMMUNOFLUORESCENCE; IN VITRO STUDY; IN VIVO STUDY; MALE; MASS SPECTROMETRY; MICROSCOPY; MOUSE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROSTATE CANCER; PROSTATE TUMOR; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

AMINO ACID SEQUENCE; ANIMALS; BOMBESIN; CALCIUM; CELL LINE, TUMOR; DIAGNOSTIC IMAGING; HEK293 CELLS; HUMANS; LIGANDS; MALE; MICE; OLIGOPEPTIDES; POLYETHYLENE GLYCOLS; POSITRON-EMISSION TOMOGRAPHY AND COMPUTED TOMOGRAPHY; PROSTATIC NEOPLASMS; RADIOCHEMISTRY; RECEPTORS, BOMBESIN; TRANSLATIONAL MEDICAL RESEARCH;

EID: 83755170780     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.111.094375     Document Type: Article

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