메뉴 건너뛰기




Volumn 31, Issue SUPPL. 1, 2012, Pages

Sequence-specific biosensors report drug-induced changes in epigenetic silencing in living cells

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; AZACITIDINE; CELL PROTEIN; INTEIN; L1PA2 PROTEIN; LUCIFERASE; REPETITIVE DNA; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN; ZINC FINGER PROTEIN 1; ZINC FINGER PROTEIN 2;

EID: 84867311168     PISSN: 10445498     EISSN: 15577430     Source Type: Journal    
DOI: 10.1089/dna.2011.1537     Document Type: Article
Times cited : (14)

References (37)
  • 2
    • 77953234794 scopus 로고    scopus 로고
    • LINE dancing in the human genome: Transposable elements and disease
    • Belancio, V.P., Deininger, P.L., and Roy-Engel, A.M. (2009). LINE dancing in the human genome: transposable elements and disease. Genome Med 1, 971-978.
    • (2009) Genome Med , vol.1 , pp. 971-978
    • Belancio, V.P.1    Deininger, P.L.2    Roy-Engel, A.M.3
  • 3
    • 34247492871 scopus 로고    scopus 로고
    • Re-activation of a dormant tumor suppressor gene maspin by designed transcription factors
    • DOI 10.1038/sj.onc.1210072, PII 1210072
    • Beltran, A., Parikh, S., Liu, Y., Cuevas, B.D., Johnson, G.L., Futscher, B.W., and Blancafort, P. (2007). Re-activation of a dormant tumor suppressor gene maspin by designed transcription factors. Oncogene 26, 2791-2798. (Pubitemid 46663828)
    • (2007) Oncogene , vol.26 , Issue.19 , pp. 2791-2798
    • Beltran, A.1    Parikh, S.2    Liu, Y.3    Cuevas, B.D.4    Johnson, G.L.5    Futscher, B.W.6    Blancafort, P.7
  • 4
    • 79953158012 scopus 로고    scopus 로고
    • The generation of zinc finger proteins by modular assembly
    • Bhakta, M.S., and Segal, D.J. (2010). The generation of zinc finger proteins by modular assembly. Methods Mol Biol 649, 3-30.
    • (2010) Methods Mol Biol , vol.649 , pp. 3-30
    • Bhakta, M.S.1    Segal, D.J.2
  • 5
    • 9444230573 scopus 로고    scopus 로고
    • Designing transcription factor architectures for drug discovery
    • DOI 10.1124/mol.104.002758
    • Blancafort, P., Segal, D.J., and Barbas, C.F., 3rd. (2004). Designing transcription factor architectures for drug discovery. Mol Pharmacol 66, 1361-1371. (Pubitemid 39564763)
    • (2004) Molecular Pharmacology , vol.66 , Issue.6 , pp. 1361-1371
    • Blancafort, P.1    Segal, D.J.2    Barbas III, C.F.3
  • 6
    • 34548529948 scopus 로고    scopus 로고
    • Phase i study ofn decitabine alone or in combination with valproic acid in acute myeloid leukemia
    • Blum, W., Klisovic, R.B., Hackanson, B., Liu, Z., Liu, S., et al. (2008). Phase I study ofn decitabine alone or in combination with valproic acid in acute myeloid leukemia. J Clin Oncol 25, 3884-3891.
    • (2008) J Clin Oncol , vol.25 , pp. 3884-3891
    • Blum, W.1    Klisovic, R.B.2    Hackanson, B.3    Liu, Z.4    Liu, S.5
  • 7
    • 0026553846 scopus 로고
    • Active LINE-1 retrotransposons in human testicular cancer
    • Bratthauer, G.L., and Fanning, T.G. (1992). Active LINE-1 retrotransposons in human testicular cancer. Oncogene 7, 507-510.
    • (1992) Oncogene , vol.7 , pp. 507-510
    • Bratthauer, G.L.1    Fanning, T.G.2
  • 8
    • 0027457418 scopus 로고
    • LINE-1 retrotransposon expression in pediatric germ cell tumors
    • Bratthauer, G.L., and Fanning, T.G. (1993). LINE-1 retrotransposon expression in pediatric germ cell tumors. Cancer 71, 2383-2386. (Pubitemid 23087783)
    • (1993) Cancer , vol.71 , Issue.7 , pp. 2383-2386
    • Bratthauer, G.L.1    Fanning, T.G.2
  • 9
    • 39749155114 scopus 로고    scopus 로고
    • Pharmacokinetics of decitabine administered as a 3-h infusion to patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS)
    • DOI 10.1007/s00280-007-0531-7
    • Cashen, A.F., Shah, A.K., Todt, L., Fisher, N., and DiPersio, J. (2008). Pharmacokinetics of decitabine administered as a 3-h infusion to patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS). Cancer Chemother Pharmacol 61, 759-766. (Pubitemid 351302031)
    • (2008) Cancer Chemotherapy and Pharmacology , vol.61 , Issue.5 , pp. 759-766
    • Cashen, A.F.1    Shah, A.K.2    Todt, L.3    Fisher, N.4    DiPersio, J.5
  • 10
    • 67649975254 scopus 로고    scopus 로고
    • Systematic evaluation of split-fluorescent proteins for the direct detection of native and methylated DNA
    • Furman, J.L., Badran, A.H., Shen, S., Stains, C.I., Hannallah, J., Segal, D.J., and Ghosh, I. (2009). Systematic evaluation of split-fluorescent proteins for the direct detection of native and methylated DNA. Bioorg Med Chem Lett 19, 3748-3751.
    • (2009) Bioorg Med Chem Lett , vol.19 , pp. 3748-3751
    • Furman, J.L.1    Badran, A.H.2    Shen, S.3    Stains, C.I.4    Hannallah, J.5    Segal, D.J.6    Ghosh, I.7
  • 11
    • 79959743101 scopus 로고    scopus 로고
    • Interleukin-6 promotes tumorigenesis by altering DNA methylation in oral cancer cells
    • Gasche, J.A., Hoffmann, J., Boland, C.R., and Goel, A. (2011). Interleukin-6 promotes tumorigenesis by altering DNA methylation in oral cancer cells. Int J Cancer 129, 1053-1063.
    • (2011) Int J Cancer , vol.129 , pp. 1053-1063
    • Gasche, J.A.1    Hoffmann, J.2    Boland, C.R.3    Goel, A.4
  • 13
    • 75449093579 scopus 로고    scopus 로고
    • The efficiency of nuclear plasmid DNA delivery is a critical determinant of transgene expression at the single cell level
    • Glover, D.J., Leyton, D.L., Moseley, G.W., and Jans, D.A. (2010). The efficiency of nuclear plasmid DNA delivery is a critical determinant of transgene expression at the single cell level. J Gene Med 12, 77-85.
    • (2010) J Gene Med , vol.12 , pp. 77-85
    • Glover, D.J.1    Leyton, D.L.2    Moseley, G.W.3    Jans, D.A.4
  • 14
    • 79952328162 scopus 로고    scopus 로고
    • Azacytidine and decitabine induce gene-specific and nonrandom DNA demethylation in human cancer cell lines
    • Hagemann, S., Heil, O., Lyko, F., and Brueckner, B. (2011). Azacytidine and decitabine induce gene-specific and nonrandom DNA demethylation in human cancer cell lines. PLoS One 6, e17388.
    • (2011) PLoS One , vol.6
    • Hagemann, S.1    Heil, O.2    Lyko, F.3    Brueckner, B.4
  • 15
    • 70149088059 scopus 로고    scopus 로고
    • Transposon silencing by piRNAs
    • Halic, M., and Moazed, D. (2009). Transposon silencing by piRNAs. Cell 138, 1058-1060.
    • (2009) Cell , vol.138 , pp. 1058-1060
    • Halic, M.1    Moazed, D.2
  • 16
    • 77953808473 scopus 로고    scopus 로고
    • Next-generation genomics: An integrative approach
    • Hawkins, R.D., Hon, G.C., and Ren, B. (2010). Next-generation genomics: an integrative approach. Nat Rev Genet 11, 476-486.
    • (2010) Nat Rev Genet , vol.11 , pp. 476-486
    • Hawkins, R.D.1    Hon, G.C.2    Ren, B.3
  • 18
    • 77953633943 scopus 로고    scopus 로고
    • The discovery of zinc fingers and their applications in gene regulation and genome manipulation
    • Klug, A. (2010). The discovery of zinc fingers and their applications in gene regulation and genome manipulation. Annu Rev Biochem 79, 213-231.
    • (2010) Annu Rev Biochem , vol.79 , pp. 213-231
    • Klug, A.1
  • 20
    • 80052831943 scopus 로고    scopus 로고
    • Exosome nanotechnology: An emerging paradigm shift in drug delivery: Exploitation of exosome nanovesicles for systemic in vivo delivery of RNAi heralds new horizons for drug delivery across biological barriers
    • Lakhal, S., and Wood, M.J. (2011). Exosome nanotechnology: an emerging paradigm shift in drug delivery: exploitation of exosome nanovesicles for systemic in vivo delivery of RNAi heralds new horizons for drug delivery across biological barriers. Bioessays 33, 737-741.
    • (2011) Bioessays , vol.33 , pp. 737-741
    • Lakhal, S.1    Wood, M.J.2
  • 23
    • 80054880942 scopus 로고    scopus 로고
    • Zinc finger-mediated live cell imaging in Arabidopsis roots
    • Lindhout, B.I., Meckel, T., and van der Zaal, B.J. (2010). Zinc finger-mediated live cell imaging in Arabidopsis roots. Methods Mol Biol 649, 383-398.
    • (2010) Methods Mol Biol , vol.649 , pp. 383-398
    • Lindhout, B.I.1    Meckel, T.2    Van Der Zaal, B.J.3
  • 24
    • 78049337305 scopus 로고    scopus 로고
    • As we bring demethylating drugs to the clinic, we better know the DICE being cast
    • Lizardi, P.M. (2010). As we bring demethylating drugs to the clinic, we better know the DICE being cast. Oncogene 29, 5772-5774.
    • (2010) Oncogene , vol.29 , pp. 5772-5774
    • Lizardi, P.M.1
  • 25
    • 17644404081 scopus 로고    scopus 로고
    • Bioavailability of azacitidine subcutaneous versus intravenous in patients with the myelodysplastic syndromes
    • DOI 10.1177/0091270004271947
    • Marcucci, G., Silverman, L., Eller, M., Lintz, L., and Beach, C.L. (2005). Bioavailability of azacitidine subcutaneous versus intravenous in patients with the myelodysplastic syndromes. J Clin Pharmacol 45, 597-602. (Pubitemid 40562951)
    • (2005) Journal of Clinical Pharmacology , vol.45 , Issue.5 , pp. 597-602
    • Marcucci, G.1    Silverman, L.2    Eller, M.3    Lintz, L.4    Beach, C.L.5
  • 26
    • 77955417371 scopus 로고    scopus 로고
    • A molecularly engineered split reporter for imaging proteinprotein interactions with positron emission tomography
    • Massoud, T.F., Paulmurugan, R., and Gambhir, S.S. (2010). A molecularly engineered split reporter for imaging proteinprotein interactions with positron emission tomography. Nat Med 16, 921-926.
    • (2010) Nat Med , vol.16 , pp. 921-926
    • Massoud, T.F.1    Paulmurugan, R.2    Gambhir, S.S.3
  • 27
    • 58749097426 scopus 로고    scopus 로고
    • Small RNAs in transcriptional gene silencing and genome defence
    • Moazed, D. (2009). Small RNAs in transcriptional gene silencing and genome defence. Nature 457, 413-420.
    • (2009) Nature , vol.457 , pp. 413-420
    • Moazed, D.1
  • 28
    • 0037036791 scopus 로고    scopus 로고
    • Protein splicing triggered by a small molecule
    • DOI 10.1021/ja026769o
    • Mootz, H.D., and Muir, T.W. (2002). Protein splicing triggered by a small molecule. J Am Chem Soc 124, 9044-9045. (Pubitemid 34847653)
    • (2002) Journal of the American Chemical Society , vol.124 , Issue.31 , pp. 9044-9045
    • Mootz, H.D.1    Muir, T.W.2
  • 29
    • 70349312354 scopus 로고    scopus 로고
    • ChIP-seq: Advantages and challenges of a maturing technology
    • Park, P.J. (2009). ChIP-seq: advantages and challenges of a maturing technology. Nat Rev Genet 10, 669-680.
    • (2009) Nat Rev Genet , vol.10 , pp. 669-680
    • Park, P.J.1
  • 30
    • 83555173292 scopus 로고    scopus 로고
    • Satellite 2 demethylation induced by 5-azacytidine is associated with missegregation of chromosomes 1 and 16 in human somatic cells
    • Prada, D., González, R., Sánchez, L., Castro, C., Fabián, E., and Herrera, L.A. (2012). Satellite 2 demethylation induced by 5-azacytidine is associated with missegregation of chromosomes 1 and 16 in human somatic cells. Mutat Res 729, 100-105.
    • (2012) Mutat Res , vol.729 , pp. 100-105
    • Prada, D.1    González, R.2    Sánchez, L.3    Castro, C.4    Fabián, E.5    Herrera, L.A.6
  • 31
    • 77956120147 scopus 로고    scopus 로고
    • Sequencespecific recognition of methylated DNA by human zinc-finger proteins
    • Sasai, N., Nakao, M., and Defossez, P.A. (2010). Sequencespecific recognition of methylated DNA by human zinc-finger proteins. Nucleic Acids Res 38, 5015-5022.
    • (2010) Nucleic Acids Res , vol.38 , pp. 5015-5022
    • Sasai, N.1    Nakao, M.2    Defossez, P.A.3
  • 32
    • 33645284007 scopus 로고    scopus 로고
    • Methylation of endogenous human retroelements in health and disease
    • DNA Methylation: Development, Genetic Disease and Cancer
    • Schulz, W.A., Steinhoff, C., and Florl, A.R. (2006). Methylation of endogenous human retroelements in health and disease. Curr Top Microbiol Immunol 310, 211-250. (Pubitemid 47400292)
    • (2006) Current Topics in Microbiology and Immunology , vol.310 , pp. 211-250
    • Schulz, W.A.1    Steinhoff, C.2    Florl, A.R.3
  • 33
    • 33845723065 scopus 로고    scopus 로고
    • Post-translational enzyme activation in an animal via optimized conditional protein splicing
    • DOI 10.1038/nchembio832, PII NCHEMBIO832
    • Schwartz, E.C., Saez, L., Young, M.W., and Muir, T.W. (2006). Post-translational enzyme activation in an animal via optimized conditional protein splicing. Nat Chem Biol 3, 50-54. (Pubitemid 46005698)
    • (2007) Nature Chemical Biology , vol.3 , Issue.1 , pp. 50-54
    • Schwartz, E.C.1    Saez, L.2    Young, M.W.3    Muir, T.W.4
  • 35
    • 79952402071 scopus 로고    scopus 로고
    • Reactivation of L1 retro-transposon by benzo(a)pyrene involves complex genetic and epigenetic regulation
    • Teneng, I., Montoya-Durango, D.E., Quertermous, J.L., Lacy, M.E., and Ramos, K.S. (2011). Reactivation of L1 retro-transposon by benzo(a)pyrene involves complex genetic and epigenetic regulation. Epigenetics 6, 355-367.
    • (2011) Epigenetics , vol.6 , pp. 355-367
    • Teneng, I.1    Montoya-Durango, D.E.2    Quertermous, J.L.3    Lacy, M.E.4    Ramos, K.S.5
  • 36
    • 78049349212 scopus 로고    scopus 로고
    • Demethylation of a LINE-1 antisense promoter in the cMet locus impairs Met signalling through induction of illegitimate transcription
    • Weber, B., Kimhi, S., Howard, G., Eden, A., and Lyko, F. (2010). Demethylation of a LINE-1 antisense promoter in the cMet locus impairs Met signalling through induction of illegitimate transcription. Oncogene 29, 5775-5784.
    • (2010) Oncogene , vol.29 , pp. 5775-5784
    • Weber, B.1    Kimhi, S.2    Howard, G.3    Eden, A.4    Lyko, F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.