Hepatoprotective Effect of MMP-19 Deficiency in a Mouse Model of Chronic Liver Fibrosis

PLoS ONE

Volumn 7, Issue 10, 2012, Pages

  Jirouskova, Marketa ^a   Zbodakova, Olga ^a   Gregor, Martin ^a   Chalupsky, Karel ^a   Sarnova, Lenka ^a   Hajduch, Marian ^b   Ehrmann, Jiri ^b   Jirkovska, Marie ^c   Sedlacek, Radislav ^a  

^a INSTITUTE OF MOLECULAR GENETICS   (Czech Republic)

^b PALACKÝ UNIVERSITY   (Czech Republic)

^c CHARLES UNIVERSITY   (Czech Republic)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CARBON TETRACHLORIDE; COLLAGEN FIBRIL; COLLAGEN TYPE 4; GELATINASE A; MATRIX METALLOPROTEINASE 19; MESSENGER RNA; PROTEIN KINASE B; SMAD3 PROTEIN; SOMATOMEDIN C; TRANSCRIPTION FACTOR SNAIL; TRANSCRIPTION FACTOR SNAIL 1; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; VIMENTIN;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BASEMENT MEMBRANE; CHRONIC DISEASE; CONTROLLED STUDY; DISEASE COURSE; DISEASE MODEL; ENZYME ACTIVITY; ENZYME DEFICIENCY; ENZYME PHOSPHORYLATION; LIVER CELL; LIVER FIBROSIS; LIVER INJURY; LIVER PROTECTION; LIVER REGENERATION; MALE; MATRIX METALLOPROTEINASE 19 DEFICIENCY; MEMBRANE DAMAGE; MOUSE; NONHUMAN; PATHOGENESIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

ANIMALS; CARBON TETRACHLORIDE POISONING; CELL PROLIFERATION; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; HEPATOCYTES; INSULIN-LIKE GROWTH FACTOR I; LIVER CIRRHOSIS; MATRIX METALLOPROTEINASES, SECRETED; MICE; MICE, KNOCKOUT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA;

EID: 84867308569     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0046271     Document Type: Article

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