Cell-surface Metalloprotease ADAM12 is Internalized by a Clathrin- and Grb2-dependent Mechanism

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Volumn 13, Issue 11, 2012, Pages 1532-1546

  Stautz, Dorte ^a   Leyme, Anthony ^a,c   Grandal, Michael Vibo ^b,d   Albrechtsen, Reidar ^a   van Deurs, Bo ^b   Wewer, Ulla ^a   Kveiborg, Marie ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c UNIVERSITÉ DE RENNES 1   (France)

^d NOVO NORDISK A S   (Denmark)

Author keywords

ADAM; ADAM12; Clathrin; Ectodomain shedding; Endocytosis; Grb2; Metalloprotease; SH3

Indexed keywords

ADAM PROTEIN; CELL SURFACE PROTEIN; CLATHRIN; CYTOPLASM PROTEIN; DISINTEGRIN AND METALLOPROTEINASE 12; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; PROTEIN SH3; UNCLASSIFIED DRUG;

ARTICLE; CELL ADHESION; CONTROLLED STUDY; ENDOCYTOSIS; ENDOSOME; ENZYME ACTIVITY; HUMAN; HUMAN CELL; INTERNALIZATION; PRIORITY JOURNAL; PROLINE RICH PROTEIN DOMAIN; PROTEIN DEGRADATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ADAM PROTEINS; BREAST NEOPLASMS; CARCINOMA; CLATHRIN; ENDOCYTOSIS; ENDOSOMES; FEMALE; GRB2 ADAPTOR PROTEIN; HEK293 CELLS; HUMANS; MEMBRANE PROTEINS; PROLINE-RICH PROTEIN DOMAINS; PROTEIN INTERACTION DOMAINS AND MOTIFS;

EID: 84867232226     PISSN: 13989219     EISSN: 16000854     Source Type: Journal    
DOI: 10.1111/j.1600-0854.2012.01405.x     Document Type: Article

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