Enantioselective synthesis of tetrahydrocarbazoles through a Michael addition/Ciamician-Plancher rearrangement sequence: Asymmetric synthesis of a potent constrained analogue of MS-245

Chemistry - A European Journal

Volumn 18, Issue 42, 2012, Pages 13250-13254

  Loh, Charles C J ^a   Raabe, Gerhard ^a   Enders, Dieter ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

Ciamician Plancher rearrangement; Michael additions; organocatalysis; tandem reactions; tetrahydrocarbazoles

Indexed keywords

CIAMICIAN-PLANCHER REARRANGEMENT; MICHAEL ADDITIONS; ORGANOCATALYSIS; TANDEM REACTION; TETRAHYDROCARBAZOLES;

ENANTIOSELECTIVITY; REACTION KINETICS;

ADDITION REACTIONS;

CARBAZOLE DERIVATIVE; INDOLE; INDOLE DERIVATIVE; N1 BENZENESULFONYL 5 METHOXY N,N DIMETHYLTRYPTAMINE; N1-BENZENESULFONYL-5-METHOXY-N,N-DIMETHYLTRYPTAMINE; SEROTONIN 6 RECEPTOR; SEROTONIN ANTAGONIST; SEROTONIN RECEPTOR; SILVER; TRYPTAMINE DERIVATIVE;

ARTICLE; CATALYSIS; CHEMISTRY; CONFORMATION; METABOLISM; STEREOISOMERISM; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

CARBAZOLES; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; INDOLES; MOLECULAR CONFORMATION; RECEPTORS, SEROTONIN; SEROTONIN ANTAGONISTS; SILVER; STEREOISOMERISM; TRYPTAMINES;

EID: 84867229078     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.201202908     Document Type: Article

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