Enantioselective Friedel-Crafts alkylations of α,β-unsaturated 2-acyl imidazoles catalyzed by bis(oxazolinyl)pyridine-scandium(III) triflate complexes

Journal of the American Chemical Society

Volumn 127, Issue 25, 2005, Pages 8942-8943

  Evans, David A ^a   Fandrick, Keith R ^a   Song, Hyun Ji ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA BETA UNSATURATED 2 ACYL N METHYLIMIDAZOLE; BIS(OXAZOLINYL)PYRIDINE; CARBON; CARBOXYLIC ACID DERIVATIVE; IMIDAZOLE DERIVATIVE; INDOLE; PYRIDINE DERIVATIVE; SCANDIUM; TRIFLUOROMETHANESULFONIC ACID; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL BOND; CHEMICAL STRUCTURE; CHIRALITY; ENANTIOSELECTIVITY; FRIEDEL CRAFTS REACTION;

ALKYLATION; CATALYSIS; IMIDAZOLES; MOLECULAR STRUCTURE; ORGANOMETALLIC COMPOUNDS; PYRIDINES; SCANDIUM; STEREOISOMERISM;

EID: 21244450251     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja052433d     Document Type: Article

References (19)

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18. All substrates explored showed increased product enantioselection with decreased catalyst loading.
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