Strategic Assay Selection for analytics in high-throughput process development: Case studies for downstream processing of monoclonal antibodies

Biotechnology Journal

Volumn 7, Issue 10, 2012, Pages 1256-1268

  Konstantinidis, Spyridon ^a   Kong, Simyee ^a   Chhatre, Sunil ^a   Velayudhan, Ajoy ^a   Heldin, Eva ^b   Titchener Hooker, Nigel ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b GE Healthcare Life Sciences   (Sweden)

Author keywords

Analytical bottleneck; HTPD; MAb; Multicriteria decision making

Indexed keywords

ANALYTES; ANALYTICAL BOTTLENECK; ANALYTICAL METHOD; BIOPROCESS DEVELOPMENT; DOWNSTREAM-PROCESSING; HIGH-THROUGHPUT; HTPD; MAB; MULTI CRITERIA DECISION MAKING; PROCESS DEVELOPMENT; PURIFICATION PROCESS; STOCHASTIC RANKING;

MONOCLONAL ANTIBODIES;

ASSAYS;

MONOCLONAL ANTIBODY;

ANALYTIC METHOD; ARTICLE; DOWNSTREAM PROCESSING; HIGH THROUGHPUT SCREENING; PERFORMANCE; PRIORITY JOURNAL; PROCESS DEVELOPMENT; PURIFICATION; STATISTICS; STRATEGIC ASSAY SELECTION;

ANTIBODIES, MONOCLONAL; CHEMISTRY TECHNIQUES, ANALYTICAL; DECISION MAKING, COMPUTER-ASSISTED; HIGH-THROUGHPUT SCREENING ASSAYS; MODELS, THEORETICAL;

EID: 84867216317     PISSN: 18606768     EISSN: 18607314     Source Type: Journal    
DOI: 10.1002/biot.201100476     Document Type: Article

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