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Volumn 13, Issue 11, 2012, Pages 2299-2307

Glycobiology in Malignant Gliomas: Expression and Functions of Galectins and Possible Therapeutic Options

Author keywords

Angiogenesis; Apoptosis; Galectin; Glioblastoma; Glioma; Immune response; Therapy

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 2; ALKYLATING AGENT; CARMUSTINE; CULLIN; CYTARABINE; GALECTIN; GALECTIN 1; GALECTIN 3; GALECTIN 8; INTERLEUKIN 10; INTERLEUKIN 13; LOMUSTINE; MICROTUBULE ASSOCIATED PROTEIN 2; NIMUSTINE; NITROSOUREA; PROTEIN BCL 2; PROTEIN KINASE C; PROTEIN P21; PROTEIN P53; TEMOZOLOMIDE; TENIPOSIDE; VASCULOTROPIN;

EID: 84867140573     PISSN: 13892010     EISSN: 18734316     Source Type: Journal    
DOI: 10.2174/138920112802502051     Document Type: Review
Times cited : (10)

References (89)
  • 3
    • 77955363593 scopus 로고    scopus 로고
    • Concurrent radiotherapy and temozolomide followed by temozolomide and sorafenib in the first-line treatment of patients with glioblastoma multiforme
    • Hainsworth, J. D.; Ervin, T.; Friedman, E.; Priego, V.; Murphy, P. B.; Clark, B. L.; Lamar, R. E. Concurrent radiotherapy and temozolomide followed by temozolomide and sorafenib in the first-line treatment of patients with glioblastoma multiforme. Cancer, 2010, 116(15),3663-3669
    • (2010) Cancer , vol.116 , Issue.15 , pp. 3663-3669
    • Hainsworth, J.D.1    Ervin, T.2    Friedman, E.3    Priego, V.4    Murphy, P.B.5    Clark, B.L.6    Lamar, R.E.7
  • 4
    • 0141576742 scopus 로고    scopus 로고
    • Neuro-oncology working group 01 trial of nimustine plus teniposide versus nimustine plus cytarabine chemotherapy in addition to involved-field radiotherapy in the first-line treatment of malignant glioma
    • Weller, M.; Muller, B.; Koch, R.; Bamberg, M.; Krauseneck, P. Neuro-oncology working group 01 trial of nimustine plus teniposide versus nimustine plus cytarabine chemotherapy in addition to involved-field radiotherapy in the first-line treatment of malignant glioma. J. Clin. Oncol., 2003, 21, 3276-3284.
    • (2003) J. Clin. Oncol. , vol.21 , pp. 3276-3284
    • Weller, M.1    Muller, B.2    Koch, R.3    Bamberg, M.4    Krauseneck, P.5
  • 6
    • 0036676661 scopus 로고    scopus 로고
    • Apoptosis in gliomas, and its role in their current and future treatment
    • Bogler, O.; Weller, M. Apoptosis in gliomas, and its role in their current and future treatment. Front Biosci., 2002, 7, 339-353.
    • (2002) Front Biosci. , vol.7 , pp. 339-353
    • Bogler, O.1    Weller, M.2
  • 11
    • 33750432843 scopus 로고    scopus 로고
    • Temozolomide 3 weeks on and 1 week off as first-line therapy for recurrent glioblastoma: Phase ii study from gruppo italiano cooperativo di neuro-oncologia (GICNO)
    • Brandes, A. A.; Tosoni, A.; Cavallo, G.; Bertorelle, R.; Gioia, V.; Franceschi, E.; Biscuola, M.; Blatt, V.; Crino, L.; Ermani, M. Temozolomide 3 weeks on and 1 week off as first-line therapy for recurrent glioblastoma: phase ii study from gruppo italiano cooperativo di neuro-oncologia (GICNO). Br. J. Cancer, 2006, 95, 1155-1160.
    • (2006) Br. J. Cancer , vol.95 , pp. 1155-1160
    • Brandes, A.A.1    Tosoni, A.2    Cavallo, G.3    Bertorelle, R.4    Gioia, V.5    Franceschi, E.6    Biscuola, M.7    Blatt, V.8    Crino, L.9    Ermani, M.10
  • 12
    • 69249154672 scopus 로고    scopus 로고
    • Rechallenge with temozolomide with different scheduling is effective in recurrent malignant gliomas
    • Strik, H.M.; Buhk, J.H.; Wrede, A.; Hoffmann, A.; Bock, C. Christmann, M.; Kaina, B. Rechallenge with temozolomide with different scheduling is effective in recurrent malignant gliomas. Mol. Med. Rep., 2008, 1, 863-869.
    • (2008) Mol. Med. Rep. , vol.1 , pp. 863-869
    • Strik, H.M.1    Buhk, J.H.2    Wrede, A.3    Hoffmann, A.4    Bock, C.5    Christmann, M.6    Kaina, B.7
  • 14
    • 62849112168 scopus 로고    scopus 로고
    • Collective behavior in cancer cell populations
    • Deisboeck, T. S.; Couzin, I. D. Collective behavior in cancer cell populations. Bioessays, 2009, 31, 190-197.
    • (2009) Bioessays , vol.31 , pp. 190-197
    • Deisboeck, T.S.1    Couzin, I.D.2
  • 16
    • 0032575705 scopus 로고    scopus 로고
    • A matter of life and cell death
    • Evan, G.; Littlewood, T. A matter of life and cell death. Science, 1998, 281, 1317-1322.
    • (1998) Science , vol.281 , pp. 1317-1322
    • Evan, G.1    Littlewood, T.2
  • 17
    • 0034867240 scopus 로고    scopus 로고
    • Molecular determinants of glioma cell migration and invasion
    • Wild-Bode, C.; Weller, M.; Wick, W. Molecular determinants of glioma cell migration and invasion. J. Neurosurg., 2001, 94, 978-984.
    • (2001) J. Neurosurg. , vol.94 , pp. 978-984
    • Wild-Bode, C.1    Weller, M.2    Wick, W.3
  • 18
    • 77953708821 scopus 로고    scopus 로고
    • Single minded 2-s (SIM2-s) gene is expressed in human GBM cells and involved in GBM invasion
    • He, Q.; Li, G.; Su, Y.; Shen, J.; Liu, Q.; Ma, X.; Zhao, P.; Zhang, J. Single minded 2-s (SIM2-s) gene is expressed in human GBM cells and involved in GBM invasion. Cancer Biol. Ther., 2010, 9, 430-436.
    • (2010) Cancer Biol. Ther. , vol.9 , pp. 430-436
    • He, Q.1    Li, G.2    Su, Y.3    Shen, J.4    Liu, Q.5    Ma, X.6    Zhao, P.7    Zhang, J.8
  • 19
    • 27944463086 scopus 로고    scopus 로고
    • Angiogenesis in gliomas: Biology and molecular pathophysiology
    • Fischer, I.; Gagner, J. P.; Law, M.; Newcomb, E. W.; Zagzag, D. Angiogenesis in gliomas: Biology and molecular pathophysiology. Brain Pathol., 2005, 15, 297-310.
    • (2005) Brain Pathol. , vol.15 , pp. 297-310
    • Fischer, I.1    Gagner, J.P.2    Law, M.3    Newcomb, E.W.4    Zagzag, D.5
  • 21
    • 0031055388 scopus 로고    scopus 로고
    • Angiogenesis in brain tumors; pathobiological and clinical aspects
    • Wesseling, P.; Ruiter, D. J.; Burger, P. C. Angiogenesis in brain tumors; pathobiological and clinical aspects. J. Neurooncol., 1997, 32, 253-265.
    • (1997) J. Neurooncol. , vol.32 , pp. 253-265
    • Wesseling, P.1    Ruiter, D.J.2    Burger, P.C.3
  • 25
    • 0041835842 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 increases microglial infiltration and aggressiveness of gliomas
    • Platten, M.; Kretz, A.; Naumann, U.; Aulwurm, S.; Egashira, K.; Isenmann, S.; Weller, M. Monocyte chemoattractant protein-1 increases microglial infiltration and aggressiveness of gliomas. Ann. Neurol., 2003, 54, 388-392.
    • (2003) Ann. Neurol. , vol.54 , pp. 388-392
    • Platten, M.1    Kretz, A.2    Naumann, U.3    Aulwurm, S.4    Egashira, K.5    Isenmann, S.6    Weller, M.7
  • 26
    • 0034118217 scopus 로고    scopus 로고
    • Glioma immunology and immunotherapy
    • Parney, I. F.; Hao, C.; Petruk, K. C. Glioma immunology and immunotherapy. Neurosurgery, 2000, 46, 778-791.
    • (2000) Neurosurgery , vol.46 , pp. 778-791
    • Parney, I.F.1    Hao, C.2    Petruk, K.C.3
  • 29
    • 0036713835 scopus 로고    scopus 로고
    • Enhancement of macrophage cytotoxicity against murine gliomas by interferon beta: Increase in nitric oxide production in response to glioma-derived soluble factors
    • Kito, T.; Kuroda, E.; Yokota, A.; Yamashita, U. Enhancement of macrophage cytotoxicity against murine gliomas by interferon beta: increase in nitric oxide production in response to glioma-derived soluble factors. J Neurosurg., 2002, 97, 619-626.
    • (2002) J Neurosurg. , vol.97 , pp. 619-626
    • Kito, T.1    Kuroda, E.2    Yokota, A.3    Yamashita, U.4
  • 30
    • 0037306435 scopus 로고    scopus 로고
    • Cytotoxicity in glioma cells due to interleukin-12 and interleukin-18-stimulated macrophages mediated by interferon-gamma-regulated nitric oxide
    • Kito, T.; Kuroda, E.; Yokota, A.; Yamashita, U. Cytotoxicity in glioma cells due to interleukin-12 and interleukin-18-stimulated macrophages mediated by interferon-gamma-regulated nitric oxide. J. Neurosurg., 2003, 98, 385-392.
    • (2003) J. Neurosurg. , vol.98 , pp. 385-392
    • Kito, T.1    Kuroda, E.2    Yokota, A.3    Yamashita, U.4
  • 34
    • 70450199686 scopus 로고    scopus 로고
    • The epidermal growth factor variant iii peptide vaccine for treatment of malignant gliomas
    • Li, G.; Mitra, S.; Wong, A. J. The epidermal growth factor variant iii peptide vaccine for treatment of malignant gliomas. Neurosurg. Clin. N. Am., 2010, 21, 87-93.
    • (2010) Neurosurg. Clin. N. Am. , vol.21 , pp. 87-93
    • Li, G.1    Mitra, S.2    Wong, A.J.3
  • 35
    • 0034951330 scopus 로고    scopus 로고
    • Animal lectins: From initial description to elaborated structural and functional classification
    • Kaltner, H.; Gabius, H. J. Animal lectins: from initial description to elaborated structural and functional classification. Adv. Exp. Med. Biol., 2001, 491, 79-94.
    • (2001) Adv. Exp. Med. Biol. , vol.491 , pp. 79-94
    • Kaltner, H.1    Gabius, H.J.2
  • 36
    • 0031959770 scopus 로고    scopus 로고
    • Galectins: Versatile modulators of cell adhesion, cell proliferation, and cell death
    • Perillo, N. L.; Marcus, M. E.; Baum, L. G. Galectins: versatile modulators of cell adhesion, cell proliferation, and cell death. J Mol. Med., 1998, 76, 402-412.
    • (1998) J Mol. Med. , vol.76 , pp. 402-412
    • Perillo, N.L.1    Marcus, M.E.2    Baum, L.G.3
  • 38
    • 43949164101 scopus 로고
    • S-Type mammalian lectins in allergic inflammation
    • Liu, F. T. S-Type mammalian lectins in allergic inflammation. Immunol. Today, 1993, 14, 486-490.
    • (1993) Immunol. Today , vol.14 , pp. 486-490
    • Liu, F.T.1
  • 39
    • 0029900083 scopus 로고    scopus 로고
    • Expression of galectin-3 modulates t-cell growth and apoptosis
    • Yang, R. Y.; Hsu, D. K.; Liu, F. T. Expression of galectin-3 modulates t-cell growth and apoptosis. Proc. Natl. Acad. Sci. USA, 1996, 93, 6737-6742.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 6737-6742
    • Yang, R.Y.1    Hsu, D.K.2    Liu, F.T.3
  • 40
    • 11144241063 scopus 로고    scopus 로고
    • Galectins as modulators of tumour progression
    • Liu, F. T.; Rabinovich, G. A. Galectins as modulators of tumour progression. Nat. Rev. Cancer, 2005, 5, 29-41.
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 29-41
    • Liu, F.T.1    Rabinovich, G.A.2
  • 42
    • 0033793141 scopus 로고    scopus 로고
    • Growth and migration markers of of rat C6 glioma cells identified by serial analysis of gene expression
    • Gunnersen, J.; Spirkoska, V.; Smith, P.; Danks, R.; Tan, S. Growth and migration markers of of rat C6 glioma cells identified by serial analysis of gene expression. Glia, 2000, 32, 146-154.
    • (2000) Glia , vol.32 , pp. 146-154
    • Gunnersen, J.1    Spirkoska, V.2    Smith, P.3    Danks, R.4    Tan, S.5
  • 43
    • 0034653127 scopus 로고    scopus 로고
    • Expression of galectin-1 mrna correlates with the malignant potential of human gliomas and expression of antisense galectin-1 inhibits the growth of 9 glioma cells
    • Yamaoka, K.; Mishima, K.; Nagashima, Y.; Asai, A.; Sanai, Y.; Kirino, T. Expression of galectin-1 mrna correlates with the malignant potential of human gliomas and expression of antisense galectin-1 inhibits the growth of 9 glioma cells. J. Neurosci., Res. 2000, 59, 722-730.
    • (2000) J. Neurosci., Res. , vol.59 , pp. 722-730
    • Yamaoka, K.1    Mishima, K.2    Nagashima, Y.3    Asai, A.4    Sanai, Y.5    Kirino, T.6
  • 45
    • 0034784518 scopus 로고    scopus 로고
    • Galectin-3: Cellular distribution and correlation with who-grade in human gliomas
    • Strik, H. M.; Deininger, M. H.; Frank, B.; Schluesener, H. J.; Meyermann, R. Galectin-3: cellular distribution and correlation with who-grade in human gliomas. J. Neurooncol., 2001, 53, 13-20.
    • (2001) J. Neurooncol. , vol.53 , pp. 13-20
    • Strik, H.M.1    Deininger, M.H.2    Frank, B.3    Schluesener, H.J.4    Meyermann, R.5
  • 46
    • 34548544720 scopus 로고    scopus 로고
    • Galectin-1 expression in human glioma cells: Modulation by ionizing radiation and effects on tumor cell proliferation and migration
    • Strik, H. M.; Schmidt, K.; Lingor, P.; Tonges, L.; Kugler, W.; Nitsche, M.; Rabinovich, G. A.; Bähr, M. Galectin-1 expression in human glioma cells: modulation by ionizing radiation and effects on tumor cell proliferation and migration. Oncol. Rep., 2007, 18, 483-488.
    • (2007) Oncol. Rep. , vol.18 , pp. 483-488
    • Strik, H.M.1    Schmidt, K.2    Lingor, P.3    Tonges, L.4    Kugler, W.5    Nitsche, M.6    Rabinovich, G.A.7    Bähr, M.8
  • 47
    • 40249088785 scopus 로고    scopus 로고
    • Varied expression and localization of multiple galectins in different cancer cell lines
    • Satelli, A.; Rao, P.S.; Gupta, P.K.; Lockman, P.R.; Srivenugopal, K.S.; Rao, U.S. Varied expression and localization of multiple galectins in different cancer cell lines. Oncol. Rep., 2008, 19, 587-594.
    • (2008) Oncol. Rep. , vol.19 , pp. 587-594
    • Satelli, A.1    Rao, P.S.2    Gupta, P.K.3    Lockman, P.R.4    Srivenugopal, K.S.5    Rao, U.S.6
  • 49
    • 33847399649 scopus 로고    scopus 로고
    • Proteomic investigation of glioblastoma cell lines treated with wild-type P53 and cytotoxic chemotherapy demonstrates an association between galectin-1 and P53 expression
    • Puchades, M.; Nilsson, C. L.; Emmett, M. R.; Aldape, K. D.; Ji, Y.; Lang, F. F.; Liu, T. J.; Conrad, C. A. Proteomic investigation of glioblastoma cell lines treated with wild-type P53 and cytotoxic chemotherapy demonstrates an association between galectin-1 and P53 expression. J. Proteome. Res., 2007, 6, 869-875.
    • (2007) J. Proteome. Res. , vol.6 , pp. 869-875
    • Puchades, M.1    Nilsson, C.L.2    Emmett, M.R.3    Aldape, K.D.4    Ji, Y.5    Lang, F.F.6    Liu, T.J.7    Conrad, C.A.8
  • 51
    • 0035194504 scopus 로고    scopus 로고
    • Galectins are differentially expressed in supratentorial pilocytic astrocytomas, astrocytomas, anaplastic astrocytomas and glioblastomas, and significantly modulate tumor astrocyte migration
    • Camby, I.; Belot; Rorive, S.; Lefranc, F.; Lahm, H.; Kaltner, H.; Hadari, Y.; Ruchoux, M. M.; Brotchi, J.; Zick, Y.; Salmon, I.; Gabius, H. J.; Kiss, R. Galectins are differentially expressed in supratentorial pilocytic astrocytomas, astrocytomas, anaplastic astrocytomas and glioblastomas, and significantly modulate tumor astrocyte migration. Brain Pathol., 2001, 11, 12-26.
    • (2001) Brain Pathol. , vol.11 , pp. 12-26
    • Camby, I.1    Belot, R.S.2    Lefranc, F.3    Lahm, H.4    Kaltner, H.5    Hadari, Y.6    Ruchoux, M.M.7    Brotchi, J.8    Zick, Y.9    Salmon, I.10    Gabius, H.J.11    Kiss, R.12
  • 53
    • 71549129574 scopus 로고    scopus 로고
    • Galectin-1 is implicated in the protein kinase C epsilon/vimentin-controlled trafficking of integrinbeta1 in glioblastoma cells
    • Fortin, S.; Le Mercier, M.; Camby, I.; Spiegl-Kreinecker, S.; Berger, W.; Lefranc, F.; Kiss, R. Galectin-1 is implicated in the protein kinase C epsilon/vimentin-controlled trafficking of integrinbeta1 in glioblastoma cells. Brain Pathol., 2010, 20, 39-49.
    • (2010) Brain Pathol. , vol.20 , pp. 39-49
    • Fortin, S.1    Le Mercier, M.2    Camby, I.3    Spiegl-Kreinecker, S.4    Berger, W.5    Lefranc, F.6    Kiss, R.7
  • 54
    • 3042742399 scopus 로고    scopus 로고
    • The role of galectins in the initiation, amplification and resolution of inflammatory response
    • Rubinstein, N.; Ilarregui, J. M.; Toscano, M. A.; Rabinovich, G. A. The role of galectins in the initiation, amplification and resolution of inflammatory response. Tissue Antigens, 2004, 64, 1-12.
    • (2004) Tissue Antigens , vol.64 , pp. 1-12
    • Rubinstein, N.1    Ilarregui, J.M.2    Toscano, M.A.3    Rabinovich, G.A.4
  • 55
    • 12144285871 scopus 로고    scopus 로고
    • Targeted inhibition of galectin-1 gene expression in tumor cells results in heightened t cell-mediated rejection; a potential mechanism of tumor-immune privilege
    • Rubinstein, N.; Alvarez, M.; Zwirner, N. W.; Toscano, M. A.; Ilarregui, J. M.; Bravo, A.; Mordoh, J.; Fainboim, L.; Podhajcer, O. L.; Rabinovich, G. A. Targeted inhibition of galectin-1 gene expression in tumor cells results in heightened t cell-mediated rejection; a potential mechanism of tumor-immune privilege. Cancer Cell 2004, 5, 241-251.
    • (2004) Cancer Cell , vol.5 , pp. 241-251
    • Rubinstein, N.1    Alvarez, M.2    Zwirner, N.W.3    Toscano, M.A.4    Ilarregui, J.M.5    Bravo, A.6    Mordoh, J.7    Fainboim, L.8    Podhajcer, O.L.9    Rabinovich, G.A.10
  • 60
    • 0030872450 scopus 로고    scopus 로고
    • Expression of the endogenous galactose-binding protein galectin-3 correlates with the malignant potential of tumors in the central nervous system
    • Bresalier, R. S.; Yan, P. S.; Byrd, J. C.; Lotan, R.; Raz, A. Expression of the endogenous galactose-binding protein galectin-3 correlates with the malignant potential of tumors in the central nervous system. Cancer, 1997, 80, 776-787.
    • (1997) Cancer , vol.80 , pp. 776-787
    • Bresalier, R.S.1    Yan, P.S.2    Byrd, J.C.3    Lotan, R.4    Raz, A.5
  • 62
    • 0032456173 scopus 로고    scopus 로고
    • Expression of adhesion factors and degrading proteins in primary and secondary glioblastomas and their precursor tumors
    • Tews, D. S.; Nissen, A. Expression of adhesion factors and degrading proteins in primary and secondary glioblastomas and their precursor tumors. Invasion Metastasis, 1998, 18, 271-284.
    • (1998) Invasion Metastasis , vol.18 , pp. 271-284
    • Tews, D.S.1    Nissen, A.2
  • 63
    • 0029781336 scopus 로고    scopus 로고
    • Distribution and characterization of microglia/macrophages in human brain tumors
    • Roggendorf, W.; Strupp, S.; Paulus, W. Distribution and characterization of microglia/macrophages in human brain tumors. Acta Neuropathol. Berl. 1996, 92, 288-293.
    • (1996) Acta Neuropathol. Berl. , vol.92 , pp. 288-293
    • Roggendorf, W.1    Strupp, S.2    Paulus, W.3
  • 64
    • 0028874589 scopus 로고
    • Expression and function of galectin-3, a betagalactoside-binding lectin, in human monocytes and macrophages
    • Liu, F. T.; Hsu, D. K.; Zuberi, R. I.; Kuwabara, I.; Chi, E. Y.; Henderson-WR, J. Expression and function of galectin-3, a betagalactoside-binding lectin, in human monocytes and macrophages. Am. J Pathol., 1995, 147, 1016-1028.
    • (1995) Am. J Pathol. , vol.147 , pp. 1016-1028
    • Liu, F.T.1    Hsu, D.K.2    Zuberi, R.I.3    Kuwabara, I.4    Chi, E.Y.5    Henderson, W.R.J.6
  • 68
    • 3343011406 scopus 로고    scopus 로고
    • NG2 proteoglycan promotes endothelial cell motility and angiogenesis via engagement of galectin3 and alphabeta1 integrin
    • Fukushi, J.; Makagiansar, I. T.; Stallcup, W. B. NG2 proteoglycan promotes endothelial cell motility and angiogenesis via engagement of galectin3 and alphabeta1 integrin. Mol. Biol. Cell, 2004, 15, 3580-3590
    • (2004) Mol. Biol. Cell , vol.15 , pp. 3580-3590
    • Fukushi, J.1    Makagiansar, I.T.2    Stallcup, W.B.3
  • 70
    • 49349113767 scopus 로고    scopus 로고
    • Runx2 Is expressed in human glioma cells and mediates the expression of galectin-3
    • Vladimirova, V.; Waha, A.; Luckerath, K.; Pesheva, P.; Probstmeier, R. Runx2 Is expressed in human glioma cells and mediates the expression of galectin-3. J. Neurosci. Res., 2008, 86, 2450-2461.
    • (2008) J. Neurosci. Res. , vol.86 , pp. 2450-2461
    • Vladimirova, V.1    Waha, A.2    Luckerath, K.3    Pesheva, P.4    Probstmeier, R.5
  • 72
    • 34248219058 scopus 로고    scopus 로고
    • SPARC upregulates MT1-MMP expression, MMP-2 activation, and the secretion and cleavage of galectin-3 in U87MG glioma cells
    • McClung, H. M.; Thomas, S. L.; Osenkowski, P.; Toth, M.; Menon, P.; Raz, A.; Fridman, R.; Rempel, S. A. SPARC upregulates MT1-MMP expression, MMP-2 activation, and the secretion and cleavage of galectin-3 in U87MG glioma cells. Neurosci. Lett., 2007, 419, 172-177.
    • (2007) Neurosci. Lett. , vol.419 , pp. 172-177
    • McClung, H.M.1    Thomas, S.L.2    Osenkowski, P.3    Toth, M.4    Menon, P.5    Raz, A.6    Fridman, R.7    Rempel, S.A.8
  • 74
    • 34848896271 scopus 로고    scopus 로고
    • Galectin-1 knockdown increases sensitivity to temozolomide in a B16F10 mouse metastatic melanoma model
    • Mathieu, V.; Le Mercier, M.; De Neve, N.; Sauvage, S.; Gras, T.; Roland, I.; Lefranc, F.; Kiss, R. Galectin-1 knockdown increases sensitivity to temozolomide in a B16F10 mouse metastatic melanoma model. J. Invest Dermatol., 2007, 127(10), 2399-2410
    • (2007) J. Invest Dermatol. , vol.127 , Issue.10 , pp. 2399-2410
    • Mathieu, V.1    Le Mercier, M.2    De Neve, N.3    Sauvage, S.4    Gras, T.5    Roland, I.6    Lefranc, F.7    Kiss, R.8
  • 75
    • 0032534494 scopus 로고    scopus 로고
    • Galectin-3 stimulates cell proliferation
    • Inohara, H.; Akahani, S.; Raz, A. Galectin-3 stimulates cell proliferation. Exp. Cell Res., 1998, 245, 294-302.
    • (1998) Exp. Cell Res. , vol.245 , pp. 294-302
    • Inohara, H.1    Akahani, S.2    Raz, A.3
  • 76
    • 0030707480 scopus 로고    scopus 로고
    • Galectin-3: A novel antiapoptotic molecule with a functional BH1 (NWGR) domain of Bcl-2 family
    • Akahani, S.; Nangia, M. P.; Inohara, H.; Kim, H. R.; Raz, A. Galectin-3: a novel antiapoptotic molecule with a functional BH1 (NWGR) domain of Bcl-2 family. Cancer Res., 1997, 57, 5272-5276.
    • (1997) Cancer Res. , vol.57 , pp. 5272-5276
    • Akahani, S.1    Nangia, M.P.2    Inohara, H.3    Kim, H.R.4    Raz, A.5
  • 77
    • 0038179723 scopus 로고    scopus 로고
    • Cost of migration: Invasion of malignant gliomas and implications for treatment
    • Giese, A.; Bjerkvig, R.; Berens, M. E.; Westphal, M. Cost of migration: invasion of malignant gliomas and implications for treatment. J. Clin. Oncol., 2003, 21, 1624-1636.
    • (2003) J. Clin. Oncol. , vol.21 , pp. 1624-1636
    • Giese, A.1    Bjerkvig, R.2    Berens, M.E.3    Westphal, M.4
  • 78
    • 34347388427 scopus 로고    scopus 로고
    • Differential phosphorylation of NG2 proteoglycan by ERK and PKCalpha helps balance cell proliferation and migration
    • Makagiansar, I. T.; Williams, S.; Mustelin, T.; Stallcup, W. B. Differential phosphorylation of NG2 proteoglycan by ERK and PKCalpha helps balance cell proliferation and migration. J. Cell Biol., 2007, 178, 155-165.
    • (2007) J. Cell Biol. , vol.178 , pp. 155-165
    • Makagiansar, I.T.1    Williams, S.2    Mustelin, T.3    Stallcup, W.B.4
  • 81
    • 0034694011 scopus 로고    scopus 로고
    • A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme
    • Rainov, N. G. A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme. Hum. Gene Ther., 2000, 11, 2389-2401.
    • (2000) Hum. Gene Ther. , vol.11 , pp. 2389-2401
    • Rainov, N.G.1
  • 82
    • 0035866813 scopus 로고    scopus 로고
    • Sublethal irradiation promotes migration and invasiveness of glioma cells: Implications for radiotherapy of human glioblastoma
    • Wild-Bode, C.; Weller, M.; Rimner, A.; Dichgans, J.; Wick, W. Sublethal irradiation promotes migration and invasiveness of glioma cells: implications for radiotherapy of human glioblastoma. Cancer Res., 2001, 61, 2744-2750.
    • (2001) Cancer Res. , vol.61 , pp. 2744-2750
    • Wild-Bode, C.1    Weller, M.2    Rimner, A.3    Dichgans, J.4    Wick, W.5
  • 84
    • 33144454670 scopus 로고    scopus 로고
    • Synthetic lactulose amines: Novel class of anticancer agents that induce tumor-cell apoptosis and inhibit galectinmediated homotypic cell aggregation and endothelial cell morphogenesis
    • Rabinovich, G. A.; Cumashi, A.; Bianco, G. A.; Ciavardelli, D.; Iurisci, I.; D'Egidio, M.; Piccolo, E.; Tinari, N.; Nifantiev, N.; Ia cobelli, S. Synthetic lactulose amines: novel class of anticancer agents that induce tumor-cell apoptosis and inhibit galectinmediated homotypic cell aggregation and endothelial cell morphogenesis. Glycobiology, 2006, 16, 210-220.
    • (2006) Glycobiology , vol.16 , pp. 210-220
    • Rabinovich, G.A.1    Cumashi, A.2    Bianco, G.A.3    Ciavardelli, D.4    Iurisci, I.5    D'Egidio, M.6    Piccolo, E.7    Tinari, N.8    Nifantiev, N.9    Ia cobelli, S.10
  • 86
    • 0035814138 scopus 로고    scopus 로고
    • Wedgelike glycodendrimers as inhibitors of binding of mammalian galectins to glycoproteins, lactose maxiclusters, and cell surface glycoconjugates
    • Andre, S.; Pieters, R. J.; Vrasidas, I.; Kaltner, H.; Kuwabara, I.; Liu, F. T.; Liskamp, R. M.; Gabius, H. J. Wedgelike glycodendrimers as inhibitors of binding of mammalian galectins to glycoproteins, lactose maxiclusters, and cell surface glycoconjugates. Chembiochem., 2001, 2, 822-830.
    • (2001) Chembiochem. , vol.2 , pp. 822-830
    • Andre, S.1    Pieters, R.J.2    Vrasidas, I.3    Kaltner, H.4    Kuwabara, I.5    Liu, F.T.6    Liskamp, R.M.7    Gabius, H.J.8


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