A protein delivery system using 30Kc19 cell-penetrating protein originating from silkworm

Biomaterials

Volumn 33, Issue 35, 2012, Pages 9127-9134

  Park, Ju Hyun ^a   Lee, Ju Hyun ^a   Park, Hee Ho ^a   Rhee, Won Jong ^b   Choi, Shin Sik ^c   Park, Tai Hyun ^a  

^a Seoul National University   (South Korea)

^b SolarLight Ltd   (South Korea)

^c Myong Ji University   (South Korea)

Author keywords

30Kc19 protein; Cell penetrating protein; In vivo transduction; Protein delivery; Protein transduction domain

Indexed keywords

BOMBYX MORI; CARGO MOLECULES; CARGO PROTEINS; GREEN FLUORESCENCE PROTEINS; HERPES SIMPLEX VIRUS; IN-VITRO; IN-VIVO; INTRAPERITONEALLY; MAMMALIAN CELL CULTURE; PROTEIN DELIVERY; PROTEIN DELIVERY SYSTEMS; PROTEIN TRANSDUCTION; PROTEIN TRANSDUCTION DOMAINS; RECOMBINANT ESCHERICHIA COLI; SUBCELLULAR COMPARTMENTS; TARGET ORGANS;

ANIMAL CELL CULTURE; ANIMALS; BACTERIOPHAGES; BLOOD; CELLS; CYTOLOGY; DISEASES; ESCHERICHIA COLI; HISTOLOGY; MOLECULAR BIOLOGY; TISSUE;

RECOMBINANT PROTEINS;

CELL PENETRATING PEPTIDE; GREEN FLUORESCENT PROTEIN; PROTEIN 30KC19; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BOMBYX MORI; CELL CULTURE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; CYTOPLASM; ESCHERICHIA COLI; FEMALE; HEMOLYMPH; IN VITRO STUDY; IN VIVO STUDY; MAMMAL CELL; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; APOPTOSIS; BOMBYX; CELL-PENETRATING PEPTIDES; DRUG CARRIERS; ENDOCYTOSIS; FEMALE; GENE EXPRESSION REGULATION; HEMOLYMPH; IMMUNOBLOTTING; INSECT PROTEINS; KIDNEY; LIVER; MICE; MICE, INBRED ICR; MICROSCOPY, FLUORESCENCE;

ANIMALIA; BOMBYX MORI; ESCHERICHIA COLI; HEXAPODA; HUMAN IMMUNODEFICIENCY VIRUS 1; MAMMALIA; MUS; SIMPLEXVIRUS;

EID: 84867139665     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.08.063     Document Type: Article

References (56)

1. Zender L., Kuhnel F., Kock R., Manns M., Kubicka S. VP22-mediated intercellular transport of p53 in hepatoma cells in vitro and in vivo. Cancer Gene Ther 2002, 9:489-496.
2. Kwon Y.D., Oh S.K., Kim H.S., Ku S.Y., Kim S.H., Choi Y.M., et al. Cellular manipulation of human embryonic stem cells by TAT-PDX1 protein transduction. Mol Ther 2005, 12:28-32.
3. Choi Y.S., Lee J.Y., Suh J.S., Kwon Y.M., Lee S.J., Chung J.K., et al. The systemic delivery of siRNAs by a cell penetrating peptide, low molecular weight protamine. Biomaterials 2010, 31:1429-1443.
4. Eguchi A., Meade B.R., Chang Y.-C., Fredrickson C.T., Willert K., Puri N., et al. Efficient siRNA delivery into primary cells by a peptide transduction domain-dsRNA binding domain fusion protein. Nat Biotechol 2009, 27:567-571.
5. Liu B.R., Huang Y.W., Winiarz J.G., Chiang H.J., Lee H.J. Intracellular delivery of quantum dots mediated by a histidine- and arginine-rich HR9 cell-penetrating peptide through the direct membrane translocation mechanism. Biomaterials 2011, 32:3520-3537.
6. Zhang K., Fang H., Chen Z., Taylor J.S., Wooley K.L. Shape effects of nanoparticles conjugated with cell-penetrating peptides (HIV Tat PTD) on CHO cell uptake. Bioconjug Chem 2008, 19:1880-1887.
7. Ruan G., Agrawal A., Marcus A.I., Nie S. Imaging and tracking of Tat peptide-conjugated quantum dots in living cells: new insights into nanoparticle uptake, intracellular transport, and vesicle shedding. J Am Chem Soc 2007, 129:14759-14766.
8. Schwarze S.R., Hruska K.A., Dowdy S.F. Protein transduction: unrestricted delivery into all cells?. Trends Cell Biol 2000, 10:290-295.
9. Wadia J.S., Dowdy S.F. Protein transduction technology. Curr Opin Biotechnol 2002, 13:52-56.
10. Frankel A.D., Pabo C.O. Cellular uptake of the tat protein from human immunodeficiency virus. Cell 1988, 55:1189-1193.
11. Green M., Loewenstein P.M. Autonomous functional domains of chemically synthesized human immunodeficiency virus tat trans-activator protein. Cell 1988, 55:1179-1188.
12. Mann D.A., Frankel A.D. Endocytosis and targeting of exogenous HIV-1 Tat protein. EMBO J 1991, 10:1733-1739.
13. Fawell S., Seery J., Daikh Y., Moore C., Chen L.L., Pepinsky B., et al. Tat-mediated delivery of heterologous proteins into cells. Proc Natl Acad Sci U S A 1994, 91:664-668.
14. Pooga M., Soomets U., Hallbrink M., Valkna A., Saar K., Rezaei K., et al. Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo. Nat Biotechnol 1998, 16:857-861.
15. Lewin M., Carlesso N., Tung C.H., Tang X.W., Cory D., Scadden D.T., et al. Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells. Nat Biotechnol 2000, 18:410-414.
16. Derossi D., Joliot A.H., Chassaing G., Prochiantz A. The third helix of the Antennapedia homeodomain translocates through biological membranes. J Biol Chem 1994, 269:10444-10450.
17. Phelan A., Elliott G., O'Hare P. Intercellular delivery of functional p53 by the herpesvirus protein VP22. Nat Biotechol 1998, 16:440-443.
18. Wadia J.S., Stan R.V., Dowdy S.F. Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis. Nat Med 2004, 10:310-315.
19. Izumi S., Fujie J., Yamada S., Tomino S. Molecular properties and biosynthesis of major plasma proteins in Bombyx mori. Biochim Biophys Acta 1981, 670:222-229.
20. Sakai N., Mori S., Izumi S., Haino-Fukushima K., Ogura T., Maekawa H., et al. Structures and expression of mRNAs coding for major plasma proteins of Bombyx mori. Biochim Biophys Acta 1988, 949:224-232.
21. Bosquet G., Guillet C., Calvez B., Chavancy G. The regulation of major haemolymph protein synthesis: changes in mRNA content during the development of Bombyx mori larvae. Insect Biochem 1989, 19:29-39.
22. Shigetoshi M., Susumu I., Shiro T. Complete nucleotide sequences of major plasma protein genes of Bombyx mori. Biochim Biophys Acta 1991, 1090:129-132.
23. Mine E., Izumi S., Katsuki M., Tomino S. Developmental and sex-dependent regulation of storage protein synthesis in the silkworm, Bombyx mori. Dev Biol 1983, 97:329-337.
24. Zhong B.X., Li J.K., Lin J.R., Liang J.S., Su S.K., Xu H.S., et al. Possible effect of 30K proteins in embryonic development of silkworm Bombyx mori. Acta Biochim Biophys Sin 2005, 37:355-361.
25. Ogawa N., Kishimoto A., Asano T., Izumi S. The homeodomain protein PBX participates in JH-related suppressive regulation on the expression of major plasma protein genes in the silkworm, Bombyx mori. Insect Biochem Mol Biol 2005, 35:217-229.
26. Kim E.J., Rhee W.J., Park T.H. Isolation and characterization of an apoptosis-inhibiting component from the hemolymph of Bombyx mori. Biochem Biophys Res Commun 2001, 285:224-228.
27. Kim E.J., Park H.J., Park T.H. Inhibition of apoptosis by recombinant 30K protein originating from silkworm hemolymph. Biochem Biophys Res Commun 2003, 308:523-528.
28. Kim E.J., Rhee W.J., Park T.H. Inhibition of apoptosis by a Bombyx mori gene. Biotechnol Prog 2004, 20:324-329.
29. Choi S.S., Rhee W.J., Kim E.J., Park T.H. Enhancement of recombinant protein production in Chinese hamster ovary cells through anti-apoptosis engineering using 30Kc6 gene. Biotechnol Bioeng 2006, 95:459-467.
30. Kim E.J., Park T.H. Anti-apoptosis engineering. Biotechnol Bioprocess Eng 2003, 8:76-82.
31. Park J.H., Park H.H., Park T.H. Cellular engineering for the high-level production of recombinant proteins in mammalian cell systems. Korean J Chem Eng 2010, 27:1042-1048.
32. Choi S.S., Rhee W.J., Park T.H. Beneficial effect of silkworm hemolymph on a CHO cell system: inhibition of apoptosis and increase of EPO production. Biotechnol Bioeng 2005, 91:793-800.
33. Vivès E., Brodin P., Lebleu B. A Truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus. J Biol Chem 1997, 272:16010-16017.
34. Gump J.M., Dowdy S.F. TAT transduction: the molecular mechanism and therapeutic prospects. Trends Mol Med 2007, 13:443-448.
35. Ma M., Nath A. Molecular determinants for cellular uptake of Tat protein of human immunodeficiency virus type 1 in brain cells. J Virol 1997, 71:2495-2499.
36. Kaplan I.M., Wadia J.S., Dowdy S.F. Cationic TAT peptide transduction domain enters cells by macropinocytosis. J Control Release 2005, 102:247-253.
37. Tünnemann G., Martin R.M., Haupt S., Patsch C., Edenhofer F., Cardoso M.C. Cargo-dependent mode of uptake and bioavailability of TAT-containing proteins and peptides in living cells. FASEB J 2006, 20:1775-1784.
38. Lundberg M., Wikstrom S., Johansson M. Cell surface adherence and endocytosis of protein transduction domains. Mol Ther 2003, 8:143-150.
39. Choi J.M., Ahn M.H., Chae W.J., Jung Y.G., Park J.C., Song H.M., et al. Intranasal delivery of the cytoplasmic domain of CTLA-4 using a novel protein transduction domain prevents allergic inflammation. Nat Med 2006, 12:574-579.
40. Schwarze S.R., Ho A., Vocero-Akbani A., Dowdy S.F. In vivo protein transduction: delivery of a biologically active protein into the mouse. Science 1999, 285:1569-1572.
41. Cai S.-R., Xu G., Becker-Hapak M., Ma M., Dowdy S.F., McLeod H.L. The kinetics and tissue distribution of protein transduction in mice. Eur J Pharm Sci 2006, 27:311-319.
42. Borstad G.C., Bryant L.R., Abel M.P., Scroggie D.A., Harris M.D., Alloway J.A. Colchicine for prophylaxis of acute flares when initiating allopurinol for chronic gouty arthritis. J Rheumatol 2004, 31:2429-2432.
43. Lee C.K., Son S.H., Park K.K., Park J.H.Y., Lim S.S., Kim S.-H., et al. Licochalcone A inhibits the growth of colon carcinoma and attenuates cisplatin-induced toxicity without a loss of chemotherapeutic efficacy in mice. Basic Clin Pharmacol Toxicol 2008, 103:48-54.
44. Richard J.P., Melikov K., Vives E., Ramos C., Verbeure B., Gait M.J., et al. Cell-penetrating peptides. J Biol Chem 2003, 278:585-590.
45. Snyder E.L., Dowdy S.F. Cell penetrating peptides in drug delivery. Pharm Res 2004, 21:389-393.
46. Rapoport M., Lorberboum-Galski H. TAT-based drug delivery system - new directions in protein delivery for new hopes?. Expert Opin Drug Deliv 2009, 6:453-463.
47. Kim M., Kim M., Kim H.Y., Kim S., Jung J., Maeng J., et al. A protein transduction domain located at the NH2-terminus of human translationally controlled tumor protein for delivery of active molecules to cells. Biomaterials 2011, 32:222-230.
48. Patlolla R.R., Desai P.R., Belay K., Singh M.S. Translocation of cell penetrating peptide engrafted nanoparticles across skin layers. Biomaterials 2010, 31:5598-5607.
49. Asoh S., Ohsawa I., Mori T., Katsura K.-I., Hiraide T., Katayama Y., et al. Protection against ischemic brain injury by protein therapeutics. Proc Natl Aca Sci U S A 2002, 99:17107-17112.
50. Popiel H.A., Nagai Y., Fujikake N., Toda T. Delivery of the aggregate inhibitor peptide QBP1 into the mouse brain using PTDs and its therapeutic effect on polyglutamine disease mice. Neurosci Lett 2009, 449:87-92.
51. Eguchi A., Dowdy S.F. siRNA delivery using peptide transduction domains. Trends Pharmacol Sci 2009, 30:341-345.
52. Kim W.J., Christensen L.V., Jo S., Yockman J.W., Jeong J.H., Kim Y.-H., et al. Cholesteryl oligoarginine delivering vascular endothelial growth factor siRNA effectively inhibits tumor growth in colon adenocarcinoma. Mol Ther 2006, 14:343-350.
53. Rao K.S., Reddy M.K., Horning J.L., Labhasetwar V. TAT-conjugated nanoparticles for the CNS delivery of anti-HIV drugs. Biomaterials 2008, 29:4429-4438.
54. Wang Z., Park J.H., Park H.H., Tan W., Park T.H. Enhancement of recombinant human EPO production and sialylation in chinese hamster ovary cells through Bombyx mori 30Kc19 gene expression. Biotechnol Bioeng 2011, 108:1634-1642.
55. Park J.H., Park H.H., Choi S.S., Park T.H. Stabilization of enzymes by the recombinant 30Kc19 protein. Process Biochem 2012, 47:164-169.
56. Yang J.-P., Ma X.-X., He Y.-X., Li W.-F., Kang Y., Bao R.B., et al. Crystal structure of the 30 K protein from the silkworm Bombyx mori reveals a new member of the β-trefoil superfamily. J Struct Biol 2011, 175:97-103.