Transition from colitis to cancer: High Wnt activity sustains the tumor-initiating potential of colon cancer stem cell precursors

Cancer Research

Volumn 72, Issue 19, 2012, Pages 5091-5100

  Shenoy, Anitha K ^b   Fisher, Robert C ^a   Butterworth, Elizabeth A ^a   Pi, Liya ^b   Chang, Lung Ji ^b   Appelman, Henry D ^c   Chang, Myron ^b   Scott, Edward W ^b   Huang, Emina H ^a,b  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE DEHYDROGENASE; WNT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER STEM CELL; CARCINOGENESIS; CLONOGENESIS; COLORECTAL CANCER; CONTROLLED STUDY; DISEASE COURSE; DOWN REGULATION; ENZYME ACTIVITY; FLUORESCENCE ACTIVATED CELL SORTING; GROWTH RATE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR XENOGRAFT; ULCERATIVE COLITIS; WNT SIGNALING PATHWAY;

ALDEHYDE DEHYDROGENASE; ANIMALS; BETA CATENIN; BLOTTING, WESTERN; CELL TRANSFORMATION, NEOPLASTIC; COLITIS; COLONIC NEOPLASMS; DISEASE PROGRESSION; EPITHELIAL CELLS; HUMANS; MICE; MICE, INBRED NOD; MICE, SCID; NEOPLASMS, EXPERIMENTAL; NEOPLASTIC STEM CELLS; RNA INTERFERENCE; SPHEROIDS, CELLULAR; TRANSPLANTATION, HETEROLOGOUS; TUMOR BURDEN; TUMOR CELLS, CULTURED; WNT SIGNALING PATHWAY;

EID: 84867133779     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-12-1806     Document Type: Article

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