Cannabidiolic acid, a major cannabinoid in fiber-type cannabis, is an inhibitor of MDA-MB-231 breast cancer cell migration

Toxicology Letters

Volumn 214, Issue 3, 2012, Pages 314-319

  Takeda, Shuso ^a   Okajima, Shunsuke ^a   Miyoshi, Hiroko ^a   Yoshida, Kazutaka ^a   Okamoto, Yoshiko ^a   Okada, Tomoko ^b   Amamoto, Toshiaki ^c   Watanabe, Kazuhito ^d   Omiecinski, Curtis J ^e   Aramaki, Hironori ^a  

^a DAIICHI UNIVERSITY OF PHARMACY   (Japan)

^b NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^c NEUES Corporation   (Japan)

^d HOKURIKU UNIVERSITY   (Japan)

^e PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

Cannabidiol; Cannabidiolic acid; Fiber type cannabis plant; MDA MB 231 cells; RhoA

Indexed keywords

CANNABIDIOLIC ACID; CANNABINOID; CYCLOOXYGENASE 2; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER CELL; CELL MIGRATION; CONTROLLED STUDY; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

ADENOCARCINOMA; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CANNABINOIDS; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME INHIBITORS; FEMALE; HUMANS; MCF-7 CELLS; RHO-ASSOCIATED KINASES; SIGNAL TRANSDUCTION;

CANNABIS;

EID: 84867129187     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2012.08.029     Document Type: Article

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