Differential effects of all-trans-retinoic acid, docosahexaenoic acid, and hexadecylphosphocholine on cisplatin-induced cytotoxicity and apoptosis in a cisplantin-sensitive and resistant human embryonal carcinoma cell line

Cancer Chemotherapy and Pharmacology

Volumn 41, Issue 6, 1998, Pages 469-476

  Timmer Bosscha, Hetty ^a   De Vries, Elisabeth G E ^a   Meijer, Coby ^a   Oosterhuis, J Wolter ^b   Mulder, Nanno H ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

cis Diamminedichloroplatinum(II); Differentiation; Embryonal carcinoma

Indexed keywords

CISPLATIN; DOCOSAHEXAENOIC ACID; MILTEFOSINE; RETINOIC ACID;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL DIFFERENTIATION; CELL SUBPOPULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DNA ADDUCT; DRUG RESISTANCE; DRUG SENSITIVITY; EMBRYONAL CARCINOMA; GERM CELL TUMOR; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; PRIORITY JOURNAL;

APOPTOSIS; CARCINOMA, EMBRYONAL; CELL DIFFERENTIATION; CELL SURVIVAL; CISPLATIN; DNA DAMAGE; DNA FRAGMENTATION; DOCOSAHEXAENOIC ACIDS; DRUG RESISTANCE, NEOPLASM; HUMANS; MALE; PHOSPHORYLCHOLINE; TRETINOIN; TUMOR CELLS, CULTURED;

EID: 0031935624     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002800050769     Document Type: Article

References (41)

1. Andrews PW (1984) Retinoic acid induces neuronal differentiation of a cloned human embryonal carcinoma cell line in vitro. Dev Biol 103: 285
2. Andrews PA, Howell SB (1990) Cellular pharmacology of cisplatin: perspectives on mechanisms of acquired resistance. Cancer Cells 2: 35
3. Andrews PW, Banting GS, Damjanov I, Araud D, Auner P (1984) Three monoclonal antibodies denning distinct differentiation antigens associated with different high molecular weight polypeptides on the surface of human embryonal carcinoma cells. Hybridoma 3: 347
4. Andrews PW, Damjanov I, Simon D, Banting GS, Carlin C, Dracopoli NC. Føgh J (1984) Pluripotent embryonal carcinoma clones derived from the human teratocarcinoma cell line tera-2. Differentiation in vivo and in vitro. J Lab Invest 50: 147
5. Barry MA, Behnke CA, Eastman A (1990) Activation of programmed cell death (apoptosis) by cisplatin, other anticancer drugs, toxins and hyperthermia. Biochem Pharmacol 40: 2353
6. Beckers T, Voegeli R, Hilgard P (1994) Molecular and cellular effects of hexadecylphosphocholine (miltefosine) in human myeloid leukaemic cell lines. Eur J Cancer 14: 2143
7. Caliaro MJ, Vitaux P, Lafon C, Lochon I, Néhmé A, Valette A, Canal P, Bugat R, Jozan S (1997) Multifactorial mechanism for the potentiation of cisplatin (CDDP) cytotoxicity by all-trans retinoic acid (ATRA) in human ovarian carcinoma cell lines. Br J Cancer 75: 333
8. Chresta CM, Hickman JA (1996) Oddball p53 in testicular tumors. Nature Med 2: 745
9. Chresta CM, Masters JRW, Hickman JA (1996) Hypersensitivity of human testicular tumors to etoposide-induced apoptosis is associated with functional p53 and a high Bax: Bcl-2 ratio. Cancer Res 56: 1834
10. Conley BA, Egorin MJ, Sridhara R, Finley R, Hemady R, Wu S, Tait NS, Van Echo DA (1997) Phase I clinical trial of all-trans retinoic acid with correlation of its pharmacokinetics and pharmacodynamics. Cancer Chemother Pharmacol 39: 291
11. Evans DL, Dive C (1993) Effects of cisplatin on the induction of apoptosis in proliferating hepatoma cells and nonproliferating immature thymocytes. Cancer Res 53: 2133
12. Evans DL, Tilby M, Dive C (1994) Differential sensitivity to the induction of apoptosis by cisplatin in proliferating and quiescent immature rat thymocytes is independent of the levels of drug accumulation and DNA adduct formation. Cancer Res 54: 1596
13. Geilen CC, Haase R, Buchner K, Wieder T, Hucho F, Reutter W (1991) The phospholipid analogue hexadecylphosphocholine inhibits protein kinase C in vitro and antagonises phorbol ester stimulated cell proliferation. Eur J Cancer 27: 1650
14. Gorczyca W, Gong J, Ardelt B, Traganos F, Darzynkiewicz Z (1993) The cell cycle related differences in susceptibility of HL-60 cells to apoptosis induced by various antitumor agents. Cancer Res 53: 3186
15. Guchelaar HJ, Timmer-Bosscha H, Dam-Meiring A, Uges DRA, Oosterhuis JW, De Vries EGE, Mulder NH (1993) Enhancement of cisplatin and etoposide cytotoxicity after all-trans retinoic-acid-induced cellular differentiation of a murine embryonal carcinoma cell line. Int J Cancer 55: 442
16. Himmelmann AW, Danhauser-Riedl S, Steinhauser G, Busch R, Modest EJ, Noseda A, Rastetter J, Vogler WR, Berdel WE (1990) Cross-resistance pattern of cell lines selected for resistance towards different cytotoxic drugs to membranetoxic phospholipids in vitro. Cancer Chemother Pharmacol 26: 437
17. Hofmann J, Doppler W, Jakob A, Maly K, Posch L, Uberall F, Grunicke HH (1988) Enhancement of the antiproliferative effect of cis-diamminedichloroplatinum(II) and nitrogen mustard by inhibitors of protein kinase C. Int J Cancer 42: 382
18. Kelly SL, Rozencweig M (1989) Resistance to platinum compounds: mechanisms and beyond. Eur J Cancer Clin Oncol 25: 1135
19. Le Ruppert KI, Masters JRW, Kneuchel R, Seegers S, Tainsky MA, Hofstaedter F, Buettner R (1992) The effect of all-trans retinoic acid on chemosensitivity of PA-I human teratocarcinoma cells and its modulation by an activated N-ras oncogene. Int J Cancer 51: 646
20. Loehrer PJ, Einhorn LH (1984) Cisplatin. Ann Intern Med 100: 704
21. Lotem J, Sachs L (1993) Regulation by bcl-2, c-myc, and p53 of susceptibility to induction of apoptosis by heat shock and cancer chemotherapy compounds in differentiation-competent and -defective myeloid leukaemic cells. Cell Growth Differ 4: 41
22. Mann SC, Andrews PA, Howell SB (1988) Comparison of lipid content, surface membrane fluidity, and temperature dependence of cis-diamminedichloroplatinum(II) accumulation in sensitive and resistant human ovarian carcinoma cells. Anticancer Res 8: 1211
23. Martin SJ, Bradley JG, Cotter TG (1990) HL-60 cells induced to differentiate toward neutrophils subsequently die via apoptosis. Clin Exp Immunol 79: 448
24. Meijer C, De Vries EGE, Dam A, Wilkinson MHF, Hollema H, Hoekstra HJ, Mulder NH (1997) Immunocytochemical analysis of cisplatin-induced platinum-DNA adducts with double fluorescence video microscopy. Br J Cancer 76: 290
25. O'Connor PM, Wassermann K, Sarang M, Magrath I, Bohr VA, Kohn K (1991) Relationship between DNA cross-links, cell cycle, and apoptosis in Burkitt's lymphoma cell lines differing in sensitivity to nitrogen mustard. Cancer Res 51: 6550
26. Oosterhuis JW, Andrews PW, De Jong B (1986) Mechanisms of therapy-related differentiation in testicular germ cell tumours. In: McBrien DCH, Slater TF (eds) Biochemical mechanisms of platinum antitumour drugs. IRL, Oxford, p 65
27. Ormerod MG, O'Neill C, Robertson D, Kelland LR, Harrap KR (1996) cis-Diamminedichloroplatinum(II)-induced cell death through apoptosis in sensitive and resistant human ovarian carcinoma cell lines. Cancer Chemother Pharmacol 37: 463
28. Pera MF, Roach S. Elliss CJ (1990) Comparative biology of mouse and human embryonal carcinoma. Cancer Surv 9: 243
29. Piacentini M, Fesus L, Melino G (1993) Multiple cell cycle access to the apoptotic death program in human neuroblastoma cells. FEBS Lett 320: 150
30. Roberts JJ, Friedlos F (1987) Quantitative estimation of cisplatin-induced DNA interstrand cross-links and their repair in mammalian cells: relationship to toxicity. Pharmacol Ther 34: 215
31. Scanlon KJ, Kashani-Sabet M, Miyachi H, Sowers LC, Rossi J (1989) Molecular basis of cisplatin resistance in human carcinomas: model systems and patients. Anticancer Res 9: 1301
32. Shevinsky LH, Knowles BB, Damjanov I, Solter D (1982) Monoclonal antibody to murine embroys defines a stage-specific embryonic antigen expressed on mouse embryos and human teratocarcimoma cells. Cell 30: 697
33. Solary E, Bertrand R, Kohn KW, Pommier Y (1993) Differential induction of apoptosis in undifferentiated and differentiated HL-60 cells by DNA topoisomerase I and II inhibitors Blood 81: 1359
34. Solter D, Knowles BB (1978) Monoclonal antibody defining a stage-specific mouse embryonic antigen (SSEA-1). Proc Natl Acad Sci USA 75: 5565
35. Soyland E, Nenseter MS, Braathen L, Drevon CA (1993) Very long chain n-3 and n-6 polyunsaturated fatty acids inhibit proliferation of human T-lymphocytes in vitro. Eur J Clin Invest 23: 112
36. Stillwell W, Ehringer W, Jenski LJ (1993) Docosahexaenoic acid increases permeability of lipid vesicles and tumour cells. Lipids 28: 103
37. Timmer-Bosscha H, Hospers GAP, Meijer C, Mulder NH, Muskiet FAJ, Martini IA, Uges DRA, De Vries EGE (1989) Influence of docosahexaenoic acid on cisplatin resistance in a human small cell lung cancer cell line. J Natl Cancer Inst 81: 1069
38. Timmer-Bosscha H, Mulder NH, De Vries EGE (1992) Modulation of cis-diamminedichloroplatinum(II) resistance: a review. Br J Cancer 66: 227
39. Timmer-Bosscha H, Timmer A, Meijer C, De Vries EGE, De Jong B, Oosterhuis JW, Mulder NH (1993) cis-Diamminedi-chloroplatinum(II) resistance in vitro and in vivo in human embryonal carcinoma cells. Cancer Res 53: 5707
40. Trump DL, Smith DC, Stiff D, Adedoyin A, Day R, Bahnson RR, Hofacker J, Branch RA (1997) A phase II trial of all-trans retinoic acid in hormone-refractory prostate cancer: a clinical trial with detailed pharmacokinetic analysis. Cancer Chemother Pharmacol 39: 349
41. Zheng B, Oihsi K, Shoji M, Eibl H, Berdel WE, Hadju J, Vogler WR, Kuo JF (1990) Inhibition of protein kinase C, (sodium plus potassium)-activated adenosine triphosphatase, and sodium pump by synthetic phospholipid analogues. Cancer Res 50: 3025