Levels of organochlorine contaminants in organic and conventional cheeses and their impact on the health of consumers: An independent study in the Canary Islands (Spain)

Food and Chemical Toxicology

Volumn 50, Issue 12, 2012, Pages 4325-4332

  Almeida González, Maira ^a,b   Luzardo, Octavio P ^a,b   Zumbado, Manuel ^a,b   Rodríguez Hernández, Ángel ^a,b   Ruiz Suárez, Norberto ^a,b   Sangil, Marta ^a,b   Camacho, María ^a,b   Henríquez Hernández, Luis A ^a,b   Boada, Luis D ^a,b  

^a UNIVERSITY OF LAS PALMAS DE GRAN CANARIA   (Spain)

^b Madrid Spain   (Spain)

Author keywords

Cheese; Dietary exposure; Organochlorine pesticides; PCBs

Indexed keywords

1,1 DICHLORO 2,2 BIS(4 CHLOROPHENYL)ETHYLENE; 2,2',4,4',5,5' HEXACHLOROBIPHENYL; ALPHA HEXACHLOROCYCLOHEXANE; DIELDRIN; DIOXIN; HEXACHLOROBENZENE; ORGANOCHLORINE PESTICIDE; POLYCHLORINATED BIPHENYL DERIVATIVE;

ARTICLE; CHEESE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; EUROPEAN UNION; FOOD CONTAMINATION; FOOD INTAKE; HEALTH HAZARD; MAXIMUM ALLOWABLE CONCENTRATION; SPAIN;

ADOLESCENT; ADULT; AGED; CHEESE; CHILD; CONSUMER PRODUCT SAFETY; DICHLORODIPHENYL DICHLOROETHYLENE; DIOXINS; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL POLLUTANTS; FEMALE; FOOD CONTAMINATION; FOOD, ORGANIC; HEXACHLOROBENZENE; HUMANS; ISLANDS; LINDANE; LINEAR MODELS; MIDDLE AGED; PESTICIDE RESIDUES; POLYCHLORINATED BIPHENYLS; SPAIN; YOUNG ADULT;

EID: 84867093736     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2012.08.058     Document Type: Article

References (42)

1. Agudo A., Goni F., Etxeandia A., Vives A., Millan E., Lopez R., Amiano P., Ardanaz E., Barricarte A., Chirlaque M.D., Dorronsoro M., Jakszyn P., Larranaga N., Martinez C., Navarro C., Rodriguez L., Sanchez M.J., Tormo M.J., Gonzalez C.A. Polychlorinated biphenyls in Spanish adults: determinants of serum concentrations. Environ. Res. 2009, 109:620-628.
2. Allen R.H., Gottlieb M., Clute E., Pongsiri M.J., Sherman J., Obrams G.I. Breast cancer and pesticides in Hawaii: the need for further study. Environ. Health Perspect. 1997, 105(Suppl 3):679-683.
3. ATSDR, (2001). Polychlorinated biphenyls. Disponible en: http://www.atsdr.cdc.gov/tfacts17.pdf.
4. Bilau M., Matthys C., Baeyens W., Bruckers L., De Backer G., Den Hond E., Keune H., Koppen G., Nelen V., Schoeters G., Van Larebeke N., Willems J.L., De Henauw S. Dietary exposure to dioxin-like compounds in three age groups: results from the Flemish environment and health study. Chemosphere 2008, 70:584-592.
5. Bordajandi L.R., Gomez G., Abad E., Rivera J., Del Mar Fernandez-Baston M., Blasco J., Gonzalez M.J. Survey of persistent organochlorine contaminants (PCBs, PCDD/Fs, and PAHs), heavy metals (Cu, Cd, Zn, Pb, and Hg), and arsenic in food samples from Huelva (Spain): levels and health implications. J. Agric. Food Chem. 2004, 52:992-1001.
6. Botella B., Crespo J., Rivas A., Cerrillo I., Olea-Serrano M.F., Olea N. Exposure of women to organochlorine pesticides in Southern Spain. Environ. Res. 2004, 96:34-40.
7. Covaci A., de Boer J., Ryan J.J., Voorspoels S., Schepens P. Distribution of organobrominated and organochlorinated contaminants in Belgian human adipose tissue. Environ. Res. 2002, 88:210-218.
8. Covaci A., Koppen G., Van Cleuvenbergen R., Schepens P., Winneke G., van Larebeke N., Nelen V., Vlietinck R., Schoeters G. Persistent organochlorine pollutants in human serum of 50-65 years old women in the Flanders Environmental and Health Study (FLEHS). Part 2: correlations among PCBs, PCDD/PCDFs and the use of predictive markers. Chemosphere 2002, 48:827-832.
9. Díaz-Díaz R., Loague K., Notario J.S. An assessment of agrochemical leaching potentials for Tenerife. J. Contam. Hydrol. 1999, 36:1-30.
10. Darnerud P.O., Atuma S., Aune M., Bjerselius R., Glynn A., Grawe K.P., Becker W. Dietary intake estimations of organohalogen contaminants (dioxins, PCB, PBDE and chlorinated pesticides, e.g. DDT) based on Swedish market basket data. Food Chem. Toxicol. 2006, 44:1597-1606.
11. Dmitrovic J., Chan S.C. Determination of polychlorinated biphenyl congeners in human milk by gas chromatography-negative chemical ionization mass spectrometry after sample clean-up by solid-phase extraction. J. Chromatogr., B: Anal. Technol. Biomed. Life Sci. 2002, 778:147-155.
12. Domingo J.L., Bocio A. Levels of PCDD/PCDFs and PCBs in edible marine species and human intake: a literature review. Environ. Int. 2007, 33:397-405.
13. Dorne J.L. Metabolism, variability and risk assessment. Toxicology 2010, 268:156-164.
14. Durand B., Dufour B., Fraisse D., Defour S., Duhem K., Le-Barillec K. Levels of PCDDs, PCDFs and dioxin-like PCBs in raw cow's milk collected in France in 2006. Chemosphere 2008, 70:689-693.
15. ENCA - Canary Islands Nutritional Survey, 1997-1998. Disponible en: http://www.gobiernodecanarias.org/sanidad/scs/1/plansalud/enca/ppal_enca.htm.
16. EU Council Regulation 315/93/EEC, 1993. Disponible en: http://ec.europa.eu/food/food/chemicalsafety/contaminants/legisl_en.print.htm.
17. Everett C.J., Frithsen I.L., Diaz V.A., Koopman R.J., Simpson W.M., Mainous A.G. Association of a polychlorinated dibenzo-p-dioxin, a polychlorinated biphenyl, and DDT with diabetes in the 1999-2002 National Health and Nutrition Examination Survey. Environ. Res. 2007, 103:413-418.
18. Fattore E., Fanelli R., Turrini A., di Domenico A. Current dietary exposure to polychlorodibenzo-p-dioxins, polychlorodibenzofurans, and dioxin-like polychlorobiphenyls in Italy. Mol. Nutr. Food Res. 2006, 50:915-921.
19. Focant J.F., Eppe G., Pirard C., Massart A.C., Andre J.E., De Pauw E. Levels and congener distributions of PCDDs, PCDFs and non-ortho PCBs in Belgian foodstuffs - assessment of dietary intake. Chemosphere 2002, 48:167-179.
20. Fries G.F. Transport of organic environmental contaminants to animal products. Rev. Environ. Contam. Toxicol. 1995, 141:71-109.
21. Hanaoka T., Takahashi Y., Kobayashi M., Sasaki S., Usuda M., Okubo S., Hayashi M., Tsugane S. Residuals of beta-hexachlorocyclohexane, dichlorodiphenyltrichloroethane, and hexachlorobenzene in serum, and relations with consumption of dietary components in rural residents in Japan. Sci. Total Environ. 2002, 286:119-127.
22. Henriquez-Hernandez L.A., Luzardo O.P., Almeida-Gonzalez M., Alvarez-Leon E.E., Serra-Majem L., Zumbado M., Boada L.D. Background levels of polychlorinated biphenyls in the population of the Canary Islands (Spain). Environ. Res. 2011, 111:10-16.
23. Holtcamp W. Obesogens: an environmental link to obesity. Environ. Health Perspect. 2012, 120:a62-a68.
24. Liem A.K., Furst P., Rappe C. Exposure of populations to dioxins and related compounds. Food Addit. Contam. 2000, 17:241-259.
25. Linares V., Perello G., Nadal M., Gomez-Catalan J., Llobet J.M., Domingo J.L. Environmental versus dietary exposure to POPs and metals: a probabilistic assessment of human health risks. J. Environ. Monit. 2000, 12:681-688.
26. Luzardo O.P., Almeida-Gonzalez M., Henriquez-Hernandez L.A., Zumbado M., Alvarez-Leon E.E., Boada L.D. Polychlorobiphenyls and organochlorine pesticides in conventional and organic brands of milk: occurrence and dietary intake in the population of the Canary Islands (Spain). Chemosphere 2012, 88:307-315.
27. Luzardo O.P., Goethals M., Zumbado M., Alvarez-Leon E.E., Cabrera F., Serra-Majem L., Boada L.D. Increasing serum levels of non-DDT-derivative organochlorine pesticides in the younger population of the Canary Islands (Spain). Sci. Total Environ. 2006, 367:129-138.
28. Luzardo O.P., Mahtani V., Troyano J.M., Alvarez de la Rosa M., Padilla-Perez A.I., Zumbado M., Almeida M., Burillo-Putze G., Boada C., Boada L.D. Determinants of organochlorine levels detectable in the amniotic fluid of women from Tenerife Island (Canary Islands, Spain). Environ. Res. 2009, 109:607-613.
29. Llobet J.M., Bocio A., Domingo J.L., Teixido A., Casas C., Muller L. Levels of polychlorinated biphenyls in foods from Catalonia, Spain: estimated dietary intake. J. Food Prot. 2003, 66:479-484.
30. Llobet J.M., Marti-Cid R., Castell V., Domingo J.L. Significant decreasing trend in human dietary exposure to PCDD/PCDFs and PCBs in Catalonia, Spain. Toxicol. Lett. 2008, 178:117-126.
31. Marin S., Villalba P., Diaz-Ferrero J., Font G., Yusa V. Congener profile, occurrence and estimated dietary intake of dioxins and dioxin-like PCBs in foods marketed in the Region of Valencia (Spain). Chemosphere 2011, 82:1253-1261.
32. Park H.Y., Hertz-Picciotto I., Sovcikova E., Kocan A., Drobna B., Trnovec T. Neurodevelopmental toxicity of prenatal polychlorinated biphenyls (PCBs) by chemical structure and activity: a birth cohort study. Environ. Health 2010, 9:51.
33. Rapaport R.A., Urban N.R., Capel P.D., Baker J.E., Looney B.B., Eisenreich S.J., Gorham E. "New" DDT inputs to North America: atmospheric deposition. Chemosphere 1985, 14:1167-1173.
34. SCF (Scientific Committee on Food), (2001). Opinion on the risk assessment of dioxins and dioxins-like PCB in food (update based on the new scientific information available since the adoption of the SCF opinion of 22 November 2000) Disponible en: http://www.europa.eu.int/comm/food/fs/sc/scf/out90_en.pdf.
35. Serra Majem L., Armas Navarro A., Ribas Barba L. Food consumption and food sources of energy and nutrients in Canary Islands (1997-98). Arch. Latinoam. Nutr. 2000, 50:23-33.
36. Serra Majem L., Ribas Barba L., Armas Navarro A., Alvarez Leon E., Sierra A. Energy and nutrient intake and risk of inadequate intakes in Canary Islands (1997-98). Arch. Latinoam. Nutr. 2000, 50:7-22.
37. Snedeker S.M. Pesticides and breast cancer risk: a review of DDT, DDE, and dieldrin. Environ. Health Perspect. 2001, 109(Suppl 1):35-47.
38. Soto A.M., Sonnenschein C., Chung K.L., Fernandez M.F., Olea N., Serrano F.O. The E-SCREEN assay as a tool to identify estrogens: an update on estrogenic environmental pollutants. Environ. Health Perspect. 1995, 103(Suppl 7):113-122.
39. Van den Berg M., Birnbaum L.S., Denison M., De Vito M., Farland W., Feeley M., Fiedler H., Hakansson H., Hanberg A., Haws L., Rose M., Safe S., Schrenk D., Tohyama C., Tritscher A., Tuomisto J., Tysklind M., Walker N., Peterson R.E. The 2005 World Health Organization reevaluation of human and Mammalian toxic equivalency factors for dioxins and dioxin-like compounds. Toxicol. Sci. 2006, 93:223-241.
40. Windal I., Vandevijvere S., Maleki M., Goscinny S., Vinkx C., Focant J.F., Eppe G., Hanot V., Van Loco J. Dietary intake of PCDD/Fs and dioxin-like PCBs of the Belgian population. Chemosphere 2010, 79:334-340.
41. Wolff M.S., Zeleniuch-Jacquotte A., Dubin N., Toniolo P. Risk of breast cancer and organochlorine exposure. Cancer Epidemiol. Biomarkers Prev. 2000, 9:271-277.
42. Zumbado M., Goethals M., Alvarez-Leon E.E., Luzardo O.P., Cabrera F., Serra-Majem L., Dominguez-Boada L. Inadvertent exposure to organochlorine pesticides DDT and derivatives in people from the Canary Islands (Spain). Sci. Total Environ. 2005, 339:49-62.